Essential functions of iron-requiring proteins in DNA replication, repair and cell cycle control

The role of the DNA damage response in zebrafish and cellular models of Diamond Blackfan anemia

(2014) N. Danilova et al.   Disease Models & Mechanisms

A review of metal-catalyzed molecular damage: protection by melatonin

(2014) Alejandro Romero et al.   JOURNAL OF PINEAL RESEARCH

Conserved electron donor complex Dre2-Tah18 is required for ribonucleotide reductase metallocofactor assembly and DNA synthesis

(2014) Y. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2

(2014) C. B. Poor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human CIA2A-FAM96A and CIA2B-FAM96B Integrate Iron Homeostasis and Maturation of Different Subsets of Cytosolic-Nuclear Iron-Sulfur Proteins

(2013) Oliver Stehling et al.   Cell Metabolism

Giardia intestinalis Incorporates Heme into Cytosolic Cytochromeb5

(2013) Jan Pyrih et al.   EUKARYOTIC CELL

Functional and structural characterisation of a viral cytochromeb5

(2013) Emma L. Reid et al.   FEBS LETTERS

Post-Transcriptional Regulation of Iron Homeostasis in Saccharomyces cerevisiae

(2013) María Martínez-Pastor et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

H-NS Is a Novel Transcriptional Modulator of the Ribonucleotide Reductase Genes in Escherichia coli

(2013) M. d. M. Cendra et al.   JOURNAL OF BACTERIOLOGY

Heme Sensor Proteins

(2013) Hazel M. Girvan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crucial function of vertebrate glutaredoxin 3 (PICOT) in iron homeostasis and hemoglobin maturation

(2013) Petra Haunhorst et al.   MOLECULAR BIOLOGY OF THE CELL

Resveratrol Protects C6 Astrocyte Cell Line against Hydrogen Peroxide-Induced Oxidative Stress through Heme Oxygenase 1

(2013) André Quincozes-Santos et al.   PLoS One

Structures of human primase reveal design of nucleotide elongation site and mode of Pol   tethering

(2013) M. L. Kilkenny et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Iron Deprivation in Cancer––Potential Therapeutic Implications

(2013) Jessica Heath et al.   Nutrients

Iron Deficiency Anemia: A Common and Curable Disease

(2013) J. L. Miller   Cold Spring Harbor Perspectives in Medicine

Function and Regulation of Yeast Ribonucleotide Reductase: Cell Cycle, Genotoxic Stress, and Iron Bioavailability

(2013) Sergi Puig et al.   Biomedical Journal

Iron Chelators with Topoisomerase-Inhibitory Activity and Their Anticancer Applications

(2012) V. Ashutosh Rao   ANTIOXIDANTS & REDOX SIGNALING

Mechanisms of Mammalian Iron Homeostasis

(2012) Kostas Pantopoulos et al.   BIOCHEMISTRY

Monothiol CGFS Glutaredoxins and BolA-like Proteins: [2Fe-2S] Binding Partners in Iron Homeostasis

(2012) Haoran Li et al.   BIOCHEMISTRY

Iron Content of Saccharomyces cerevisiae Cells Grown under Iron-Deficient and Iron-Overload Conditions

(2012) Gregory P. Holmes-Hampton et al.   BIOCHEMISTRY

Metabolic remodeling in iron-deficient fungi

(2012) Caroline C. Philpott et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The role of mitochondria in cellular iron–sulfur protein biogenesis and iron metabolism

(2012) Roland Lill et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cyclin F-Mediated Degradation of Ribonucleotide Reductase M2 Controls Genome Integrity and DNA Repair

(2012) Vincenzo D'Angiolella et al.   CELL

Biogenesis of iron-sulfur clusters in mammalian cells: new insights and relevance to human disease

(2012) T. A. Rouault   Disease Models & Mechanisms

Metalloreductase Steap3 coordinates the regulation of iron homeostasis and inflammatory responses

(2012) F. Zhang et al.   HAEMATOLOGICA

Iron-Induced Dissociation of the Aft1p Transcriptional Regulator from Target Gene Promoters Is an Initial Event in Iron-Dependent Gene Suppression

(2012) R. Ueta et al.   MOLECULAR AND CELLULAR BIOLOGY

Stochastic simulation for the inference of transcriptional control network of yeast cyclins genes

(2012) Jiri Vohradsky   NUCLEIC ACIDS RESEARCH

DNA helicase and helicase-nuclease enzymes with a conserved iron-sulfur cluster

(2012) Y. Wu et al.   NUCLEIC ACIDS RESEARCH

Dysregulation of IRP1-Mediated Iron Metabolism Causes Gamma Ray-specific Radioresistance in Leukemia Cells

(2012) Kurtis J. Haro et al.   PLoS One

MMS19 Assembles Iron-Sulfur Proteins Required for DNA Metabolism and Genomic Integrity

(2012) O. Stehling et al.   SCIENCE

MMS19 Links Cytoplasmic Iron-Sulfur Cluster Assembly to DNA Metabolism

(2012) K. Gari et al.   SCIENCE

Control of Systemic Iron Homeostasis by the Hemojuvelin-Hepcidin Axis

(2012) An-Sheng Zhang   Advances in Nutrition

Regulation of iron transport and the role of transferrin

(2011) Konstantinos Gkouvatsos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Functional characterization of the Saccharomyces cerevisiae protein Chl1 reveals the role of sister chromatid cohesion in the maintenance of spindle length during S-phase arrest

(2011) Suparna Laha et al.   BMC GENETICS

Iron–sulphur clusters in nucleic acid processing enzymes

(2011) Malcolm F White et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

A mammalian monothiol glutaredoxin, Grx3, is critical for cell cycle progression during embryogenesis

(2011) Ning-Hui Cheng et al.   FEBS Journal

Iron-responsive Transcription Factor Aft1 Interacts with Kinetochore Protein Iml3 and Promotes Pericentromeric Cohesin

(2011) Akil Hamza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Ribonucleotide Reductase in Response to Iron Deficiency

(2011) Nerea Sanvisens et al.   MOLECULAR CELL

Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes

(2011) Daili J A Netz et al.   Nature Chemical Biology

The Major Roles of DNA Polymerases Epsilon and Delta at the Eukaryotic Replication Fork Are Evolutionarily Conserved

(2011) Izumi Miyabe et al.   PLoS Genetics

Human Iron−Sulfur Cluster Assembly, Cellular Iron Homeostasis, and Disease

(2010) Hong Ye et al.   BIOCHEMISTRY

Cytosolic Monothiol Glutaredoxins Function in Intracellular Iron Sensing and Trafficking via Their Bound Iron-Sulfur Cluster

(2010) Ulrich Mühlenhoff et al.   Cell Metabolism

Candida albicans Cyclin Clb4 Carries S-Phase Cyclin Activity

(2010) Ayala Ofir et al.   EUKARYOTIC CELL

Functional Genomics Analysis of the Saccharomyces cerevisiae Iron Responsive Transcription Factor Aft1 Reveals Iron-Independent Functions

(2010) S. Berthelet et al.   GENETICS

Multiple regulatory mechanisms act in concert to control ferroportin expression and heme iron recycling by macrophages

(2010) C. Beaumont   HAEMATOLOGICA

Metabolic Response to Iron Deficiency in Saccharomyces cerevisiae

(2010) Minoo Shakoury-Elizeh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ZRT/IRT-like Protein 14 (ZIP14) Promotes the Cellular Assimilation of Iron from Transferrin

(2010) Ningning Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tah18 transfers electrons to Dre2 in cytosolic iron-sulfur protein biogenesis

(2010) Daili J A Netz et al.   Nature Chemical Biology

Highly mutagenic and severely imbalanced dNTP pools can escape detection by the S-phase checkpoint

(2010) Dinesh Kumar et al.   NUCLEIC ACIDS RESEARCH

Dietary iron-deficient anemia induces a variety of metabolic changes and even apoptosis in rat liver: a DNA microarray study

(2010) Asuka Kamei et al.   PHYSIOLOGICAL GENOMICS

Shared Active Site Architecture between the Large Subunit of Eukaryotic Primase and DNA Photolyase

(2010) Ludovic Sauguet et al.   PLoS One

Cell Death Mechanisms and Their Implications in Toxicology

(2010) Sten Orrenius et al.   TOXICOLOGICAL SCIENCES

The Yeast Iron Regulatory Proteins Grx3/4 and Fra2 Form Heterodimeric Complexes Containing a [2Fe-2S] Cluster with Cysteinyl and Histidyl Ligation

(2009) Haoran Li et al.   BIOCHEMISTRY

Mammalian iron transport

(2009) Gregory Jon Anderson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Iron Acquisition and Transcriptional Regulation

(2009) Craig D. Kaplan et al.   CHEMICAL REVIEWS

Trafficking of Heme and Porphyrins in Metazoa

(2009) Scott Severance et al.   CHEMICAL REVIEWS

FANCM Connects the Genome Instability Disorders Bloom's Syndrome and Fanconi Anemia

(2009) Andrew J. Deans et al.   MOLECULAR CELL

Nramp1 promotes efficient macrophage recycling of iron following erythrophagocytosis in vivo

(2009) S. Soe-Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of Iron Supply on the Kinetics of Recovery of Photosynthesis in Cd-stressed Poplar (Populus glauca)

(2008) Ádám Solti et al.   ANNALS OF BOTANY

Maturation of Iron-Sulfur Proteins in Eukaryotes: Mechanisms, Connected Processes, and Diseases

(2008) Roland Lill et al.   Annual Review of Biochemistry

Systemic Iron Homeostasis and the Iron-Responsive Element/Iron-Regulatory Protein (IRE/IRP) Regulatory Network

(2008) Martina U. Muckenthaler et al.   Annual Review of Nutrition

CIAPIN1 inhibits the growth and proliferation of clear cell renal cell carcinoma

(2008) Lijie He et al.   CANCER LETTERS

Welcome the Family of FANCJ-like Helicases to the Block of Genome Stability Maintenance Proteins

(2008) Y. Wu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Role of NADPH-Cytochrome P450 Reductase and Cytochrome-b5/NADH-b5 Reductase in Variability of CYP3A Activity in Human Liver Microsomes

(2008) L. Gan et al.   DRUG METABOLISM AND DISPOSITION

Loss of Ncb5or Results in Impaired Fatty Acid Desaturation, Lipoatrophy, and Diabetes

(2008) Kevin Larade et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Heme-Regulatory Motif Mediates Heme-Dependent Degradation of the Circadian Factor Period 2

(2008) J. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

Dre2, a Conserved Eukaryotic Fe/S Cluster Protein, Functions in Cytosolic Fe/S Protein Biogenesis

(2008) Y. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Influence of nutritional iron deficiency anemia on DNA stability and lipid peroxidation in rats

(2008) Javier Díaz-Castro et al.   NUTRITION