Storage lipid studies in tuberculosis reveal that foam cell biogenesis is disease-specific

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mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation

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Morphoproteomic-Guided Host-Directed Therapy for Tuberculosis

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High Prevalence and Heterogeneity of Diabetes in Patients With TB in South India

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Rewiring cellular metabolism via the AKT/mTOR pathway contributes to host defence againstMycobacterium tuberculosisin human and murine cells

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Inflammatory signaling in human tuberculosis granulomas is spatially organized

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Double Trouble: Prevalence and Factors Associated with Tuberculosis and Diabetes Comorbidity in Bangladesh

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Caspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease

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Polarized THG Microscopy Identifies Compositionally Different Lipid Droplets in Mammalian Cells

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Mycobacterium lepraeintracellular survival relies on cholesterol accumulation in infected macrophages: a potential target for new drugs for leprosy treatment

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Self-eating in the plaque: what macrophage autophagy reveals about atherosclerosis

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Autophagy in Tuberculosis

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A Central Role for mTOR in Lipid Homeostasis

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Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug-resistant tuberculosis

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High-Sensitivity MALDI-MRM-MS Imaging of Moxifloxacin Distribution in Tuberculosis-Infected Rabbit Lungs and Granulomatous Lesions

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mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

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TLR6-Driven Lipid Droplets in Mycobacterium leprae-Infected Schwann Cells: Immunoinflammatory Platforms Associated with Bacterial Persistence

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Cytokines, macrophage lipid metabolism and foam cells: Implications for cardiovascular disease therapy

(2011) James E. McLaren et al.   PROGRESS IN LIPID RESEARCH

mTOR couples cellular nutrient sensing to organismal metabolic homeostasis

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Mycobacterium tuberculosis Uses Host Triacylglycerol to Accumulate Lipid Droplets and Acquires a Dormancy-Like Phenotype in Lipid-Loaded Macrophages

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Modulation of lipid droplets by Mycobacterium leprae in Schwann cells: a putative mechanism for host lipid acquisition and bacterial survival in phagosomes

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TORC-Specific Phosphorylation of Mammalian Target of Rapamycin (mTOR): Phospho-Ser2481 Is a Marker for Intact mTOR Signaling Complex 2

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Triacylglycerol Utilization Is Required for Regrowth of In Vitro Hypoxic Nonreplicating Mycobacterium bovis Bacillus Calmette-Guerin

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Mycobacterium bovis Bacillus Calmette-Guerin Infection Induces TLR2-Dependent Peroxisome Proliferator-Activated Receptor   Expression and Activation: Functions in Inflammation, Lipid Metabolism, and Pathogenesis

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Lipid droplet formation in leprosy: Toll-like receptor-regulated organelles involved in eicosanoid formation and Mycobacterium leprae pathogenesis

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TNF-alpha stimulates the ACAT1 expression in differentiating monocytes to promote the CE-laden cell formation

(2009) Lei Lei et al.   JOURNAL OF LIPID RESEARCH

Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates

(2009) Viktor I. Korolchuk et al.   MOLECULAR CELL

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(2009) Rajat Singh et al.   NATURE

Foamy macrophages and the progression of the human tuberculosis granuloma

(2009) David G Russell et al.   NATURE IMMUNOLOGY

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(2009) Viviane Z. Rocha et al.   Nature Reviews Cardiology

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Genome-wide analysis of SREBP-1 binding in mouse liver chromatin reveals a preference for promoter proximal binding to a new motif

(2009) Y.-K. Seo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates

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Tumor Necrosis Factor-α Can Provoke Cleavage and Activation of Sterol Regulatory Element-binding Protein in Ethanol-exposed Cells via a Caspase-dependent Pathway That Is Cholesterol Insensitive

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Separation of cellular nonpolar neutral lipids by normal-phase chromatography and analysis by electrospray ionization mass spectrometry

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Foamy Macrophages from Tuberculous Patients' Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence

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