Fine Tuning Inflammation at the Front Door: Macrophage Complement Receptor 3-mediates Phagocytosis and Immune Suppression for Francisella tularensis

Evasion of Complement-Mediated Lysis and Complement C3 Deposition Are Regulated by Francisella tularensis Lipopolysaccharide O Antigen

(2014) C. D. Clay et al.   JOURNAL OF IMMUNOLOGY

Cholesterol-Rich Membrane Rafts and Lyn Are Involved in Phagocytosis during Pseudomonas aeruginosa Infection

(2014) S. Kannan et al.   JOURNAL OF IMMUNOLOGY

A Mathematical Model of CR3/TLR2 Crosstalk in the Context of Francisella tularensis Infection

(2012) Rachel Leander et al.   PLoS Computational Biology

Phagocytic Receptors Dictate Phagosomal Escape and Intracellular Proliferation of Francisella tularensis

(2011) Henriette Geier et al.   INFECTION AND IMMUNITY

TLR2 Signaling Contributes to Rapid Inflammasome Activation during F. novicida Infection

(2011) Crystal L. Jones et al.   PLoS One

Host-Adaptation of Francisella tularensis Alters the Bacterium's Surface-Carbohydrates to Hinder Effectors of Innate and Adaptive Immunity

(2011) Tiffany M. Zarrella et al.   PLoS One

Multiscale simulations suggest a mechanism for integrin inside-out activation

(2011) A. C. Kalli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Francisella Subverts Innate Immune Signaling: Focus On PI3K/Akt

(2011) Thomas John Cremer et al.   Frontiers in Microbiology

NOD2 controls the nature of the inflammatory response and subsequent fate of Mycobacterium tuberculosis and M. bovis BCG in human macrophages

(2010) Michelle N. Brooks et al.   CELLULAR MICROBIOLOGY

Indirect Inhibition of Toll-like Receptor and Type I Interferon Responses by ITAM-Coupled Receptors and Integrins

(2010) Lu Wang et al.   IMMUNITY

Tularemia Pneumonia

(2010) Lora D. Thomas et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Objections to the transfer of Francisella novicida to the subspecies rank of Francisella tularensis

(2010) A. Johansson et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Activation of Murine Macrophages via TLR2 and TLR4 Is Negatively Regulated by a Lyn/PI3K Module and Promoted by SHIP1

(2010) S. Keck et al.   JOURNAL OF IMMUNOLOGY

Phosphatidylinositol 3-Kinase Activation Attenuates the TLR2-Mediated Macrophage Proinflammatory Cytokine Response to Francisella tularensis Live Vaccine Strain

(2010) E. A. Medina et al.   JOURNAL OF IMMUNOLOGY

Deletion of ripA Alleviates Suppression of the Inflammasome and MAPK by Francisella tularensis

(2010) M. T.-H. Huang et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium tuberculosis Activates Human Macrophage Peroxisome Proliferator-Activated Receptor   Linking Mannose Receptor Recognition to Regulation of Immune Responses

(2010) M. V. S. Rajaram et al.   JOURNAL OF IMMUNOLOGY

Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b

(2010) Chaofeng Han et al.   NATURE IMMUNOLOGY

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Microbial Hijacking of Complement-Toll-Like Receptor Crosstalk

(2010) M. Wang et al.   Science Signaling

Crosstalk pathways between Toll-like receptors and the complement system

(2010) George Hajishengallis et al.   TRENDS IN IMMUNOLOGY

The Ins and Outs of Leukocyte Integrin Signaling

(2009) Clare L. Abram et al.   Annual Review of Immunology

Molecular Epidemiology ofFrancisella tularensisin the United States

(2009) Kiersten J. Kugeler et al.   CLINICAL INFECTIOUS DISEASES

Mannose Receptor-Dependent Delay in Phagosome Maturation by Mycobacterium avium Glycopeptidolipids

(2009) L. Sweet et al.   INFECTION AND IMMUNITY

A TIR Domain Variant of MyD88 Adapter-like (Mal)/TIRAP Results in Loss of MyD88 Binding and Reduced TLR2/TLR4 Signaling

(2009) Kamalpreet Nagpal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling

(2009) Leah E. Cole et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cross-regulation of signaling by ITAM-associated receptors

(2009) Lionel B Ivashkiv   NATURE IMMUNOLOGY

TLR–Dependent Control of Francisella tularensis Infection and Host Inflammatory Responses

(2009) Allison L. Abplanalp et al.   PLoS One

MiR-155 Induction by F. novicida but Not the Virulent F. tularensis Results in SHIP Down-Regulation and Enhanced Pro-Inflammatory Cytokine Response

(2009) Thomas J. Cremer et al.   PLoS One

CD14-Mac-1 interactions in Bacillus anthracis spore internalization by macrophages

(2009) C. Oliva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel receptor – ligand pathway for entry of Francisella tularensis in monocyte-like THP-1 cells: interaction between surface nucleolin and bacterial elongation factor Tu

(2008) Monique Barel et al.   BMC MICROBIOLOGY

The diverse functions of Src family kinases in macrophages

(2008) Clare et al.   Frontiers in Bioscience-Landmark

Infected-Host-Cell Repertoire and Cellular Response in the Lung following Inhalation of Francisella tularensis Schu S4, LVS, or U112

(2008) J. D. Hall et al.   INFECTION AND IMMUNITY

Initial Delay in the Immune Response to Francisella tularensis Is Followed by Hypercytokinemia Characteristic of Severe Sepsis and Correlating with Upregulation and Release of Damage-Associated Molecular Patterns

(2008) C. A. Mares et al.   INFECTION AND IMMUNITY

Direct and Indirect Impairment of Human Dendritic Cell Function by Virulent Francisella tularensis Schu S4

(2008) J. C. Chase et al.   INFECTION AND IMMUNITY

Subversion of complement activation at the bacterial surface promotes serum resistance and opsonophagocytosis of Francisella tularensis

(2008) Abdelhakim Ben Nasr et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A role of macrophage complement receptor CRIg in immune clearance and inflammation

(2008) Jeannie Q. He et al.   MOLECULAR IMMUNOLOGY

Microarray Analysis of Human Monocytes Infected with Francisella tularensis Identifies New Targets of Host Response Subversion

(2008) Jonathan P. Butchar et al.   PLoS One