Multiscale simulations suggest a mechanism for integrin inside-out activation
Published 2011 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Multiscale simulations suggest a mechanism for integrin inside-out activation
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 108, Issue 29, Pages 11890-11895
Publisher
Proceedings of the National Academy of Sciences
Online
2011-07-06
DOI
10.1073/pnas.1104505108
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- From Coarse Grained to Atomistic: A Serial Multiscale Approach to Membrane Protein Simulations
- (2011) Phillip J. Stansfeld et al. Journal of Chemical Theory and Computation
- Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation
- (2010) Benjamin T Goult et al. EMBO JOURNAL
- NMR analysis of the IIb 3 cytoplasmic interaction suggests a mechanism for integrin regulation
- (2010) D. G. Metcalf et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- G Protein Subunit G 13 Binds to Integrin IIb 3 and Mediates Integrin "Outside-In" Signaling
- (2010) H. Gong et al. SCIENCE
- The Structure of the Talin/Integrin Complex at a Lipid Bilayer: An NMR and MD Simulation Study
- (2010) Antreas C. Kalli et al. STRUCTURE
- The Structure of the Talin Head Reveals a Novel Extended Conformation of the FERM Domain
- (2010) Paul R. Elliott et al. STRUCTURE
- Molecular Dynamics Simulations of the Dimerization of Transmembrane α-Helices
- (2009) Emi Psachoulia et al. ACCOUNTS OF CHEMICAL RESEARCH
- PX- and FYVE-Mediated Interactions with Membranes: Simulation Studies
- (2009) Emi Psachoulia et al. BIOCHEMISTRY
- Interactions of platelet integrin αΙΙband β3transmembrane domains in mammalian cell membranes and their role in integrin activation
- (2009) Chungho Kim et al. BLOOD
- Systematic multiscale simulation of membrane protein systems
- (2009) Gary S Ayton et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- The structure of an integrin/talin complex reveals the basis of inside-out signal transduction
- (2009) Nicholas J Anthis et al. EMBO JOURNAL
- The structure of the integrin αIIbβ3 transmembrane complex explains integrin transmembrane signalling
- (2009) Tong-Lay Lau et al. EMBO JOURNAL
- Three-dimensional Model of Human Platelet Integrin αIIbβ3 in Solution Obtained by Small Angle Neutron Scattering
- (2009) Aurora Nogales et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Structure of an Interdomain Complex That Regulates Talin Activity
- (2009) Benjamin T. Goult et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- New PI(4,5)P2- and membrane proximal integrin–binding motifs in the talin head control β3-integrin clustering
- (2009) Frédéric Saltel et al. JOURNAL OF CELL BIOLOGY
- Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragment
- (2009) Jian-Ping Xiong et al. JOURNAL OF CELL BIOLOGY
- Integrin signalling at a glance
- (2009) D. S. Harburger et al. JOURNAL OF CELL SCIENCE
- Multiple Approaches Converge on the Structure of the Integrin αIIb/β3 Transmembrane Heterodimer
- (2009) Douglas G. Metcalf et al. JOURNAL OF MOLECULAR BIOLOGY
- The structure and function of platelet integrins
- (2009) J. S. BENNETT et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- The Structure of a Receptor with Two Associating Transmembrane Domains on the Cell Surface: Integrin αIIbβ3
- (2009) Jieqing Zhu et al. MOLECULAR CELL
- Structure of an integrin IIb 3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation
- (2009) J. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Consensus motif for integrin transmembrane helix association
- (2009) B. W. Berger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interactions of the Pleckstrin Homology Domain with Phosphatidylinositol Phosphate and Membranes: Characterization via Molecular Dynamics Simulations†
- (2008) Emi Psachoulia et al. BIOCHEMISTRY
- Helix−Helix Interactions in Membrane Proteins: Coarse-Grained Simulations of Glycophorin A Helix Dimerization†
- (2008) Emi Psachoulia et al. BIOCHEMISTRY
- Coarse-Grained Molecular Dynamics Simulations of the Energetics of Helix Insertion into a Lipid Bilayer†
- (2008) Peter J. Bond et al. BIOCHEMISTRY
- Structure of the Integrin β3 Transmembrane Segment in Phospholipid Bicelles and Detergent Micelles†
- (2008) Tong-Lay Lau et al. BIOCHEMISTRY
- NMR Solution Conformations and Interactions of Integrin αLβ2 Cytoplasmic Tails
- (2008) Anirban Bhunia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure of the Integrin αIIb Transmembrane Segment
- (2008) Tong-Lay Lau et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Talin at a glance
- (2008) D. R. Critchley et al. JOURNAL OF CELL SCIENCE
- The MARTINI Coarse-Grained Force Field: Extension to Proteins
- (2008) Luca Monticelli et al. Journal of Chemical Theory and Computation
- Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces
- (2008) Jianghai Zhu et al. MOLECULAR CELL
- Transmembrane and cytoplasmic domains in integrin activation and protein-protein interactions (Review)
- (2008) Kate L. Wegener et al. MOLECULAR MEMBRANE BIOLOGY
- Integrin Conformational Regulation: Uncoupling Extension/Tail Separation from Changes in the Head Region by a Multiresolution Approach
- (2008) Mattia Rocco et al. STRUCTURE
- Coarse-Grained MD Simulations of Membrane Protein-Bilayer Self-Assembly
- (2008) Kathryn A. Scott et al. STRUCTURE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started