Reduced monocyte and macrophage TNFSF15/TL1A expression is associated with susceptibility to inflammatory bowel disease
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Title
Reduced monocyte and macrophage TNFSF15/TL1A expression is associated with susceptibility to inflammatory bowel disease
Authors
Keywords
Monocytes, T cells, Inflammatory bowel disease, Genetic loci, Molecular genetics, Cytokines, Macrophages, Gene expression
Journal
PLoS Genetics
Volume 14, Issue 9, Pages e1007458
Publisher
Public Library of Science (PLoS)
Online
2018-09-11
DOI
10.1371/journal.pgen.1007458
References
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Note: Only part of the references are listed.- Fine-mapping inflammatory bowel disease loci to single-variant resolution
- (2017) Hailiang Huang et al. NATURE
- Genetic effects on gene expression across human tissues
- (2017) François Aguet et al. NATURE
- Analysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease
- (2017) J. Kenneth Baillie et al. PLoS Genetics
- Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens
- (2016) Yohann Nédélec et al. CELL
- IL23R (Interleukin 23 Receptor) Variants Protective against Inflammatory Bowel Diseases (IBD) Display Loss of Function due to Impaired Protein Stability and Intracellular Trafficking
- (2016) Durga Sivanesan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Novel Role for TL1A/DR3 in Protection against Intestinal Injury and Infection
- (2016) Li-Guo Jia et al. JOURNAL OF IMMUNOLOGY
- Fine-mapping analysis revealed complex pleiotropic effect and tissue-specific regulatory mechanism of TNFSF15 in primary biliary cholangitis, Crohn’s disease and leprosy
- (2016) Yonghu Sun et al. Scientific Reports
- Targeted genomic analysis reveals widespread autoimmune disease association with regulatory variants in the TNF superfamily cytokine signalling network
- (2016) Arianne C. Richard et al. Genome Medicine
- Insight into Genotype-Phenotype Associations through eQTL Mapping in Multiple Cell Types in Health and Immune-Mediated Disease
- (2016) James E. Peters et al. PLoS Genetics
- The functional impact of the intestinal microbiome on mucosal immunity and systemic autoimmunity
- (2015) Randy S. Longman et al. CURRENT OPINION IN RHEUMATOLOGY
- Human group3 innate lymphoid cells express DR3 and respond to TL1A with enhanced IL-22 production and IL-2-dependent proliferation
- (2015) Yong-Oon Ahn et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The TNF-Family Ligand TL1A and Its Receptor DR3 Promote T Cell–Mediated Allergic Immunopathology by Enhancing Differentiation and Pathogenicity of IL-9–Producing T Cells
- (2015) Arianne C. Richard et al. JOURNAL OF IMMUNOLOGY
- The TNF-family cytokine TL1A: from lymphocyte costimulator to disease co-conspirator
- (2015) Arianne C. Richard et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
- (2015) Jimmy Z Liu et al. NATURE GENETICS
- Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells
- (2015) Erik Arner et al. SCIENCE
- The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
- (2015) et al. SCIENCE
- NOD1 and NOD2: Signaling, Host Defense, and Inflammatory Disease
- (2014) Roberta Caruso et al. IMMUNITY
- Macrophages in intestinal homeostasis and inflammation
- (2014) Calum C. Bain et al. IMMUNOLOGICAL REVIEWS
- CX3CR1+mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22
- (2014) Randy S. Longman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3
- (2014) Aditya Murthy et al. NATURE
- Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice
- (2014) Calum C Bain et al. NATURE IMMUNOLOGY
- Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense
- (2014) K. G. Lassen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ATNFSF15disease-risk polymorphism increases pattern-recognition receptor-induced signaling through caspase-8–induced IL-1
- (2014) Matija Hedl et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes
- (2014) T. Raj et al. SCIENCE
- Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells
- (2014) M. N. Lee et al. SCIENCE
- Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression
- (2014) B. P. Fairfax et al. SCIENCE
- Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
- (2014) Claudia Giambartolomei et al. PLoS Genetics
- Recent advances in inflammatory bowel disease: mucosal immune cells in intestinal inflammation
- (2013) M Zaeem Cader et al. GUT
- TNF-like Ligand 1A (TL1A) Gene Knockout Leads to Ameliorated Collagen-Induced Arthritis in Mice: Implication of TL1A in Humoral Immune Responses
- (2013) X. Wang et al. JOURNAL OF IMMUNOLOGY
- High Intestinal and Systemic Levels of Interleukin-23/T-Helper 17 Pathway in Chinese Patients with Inflammatory Bowel Disease
- (2013) Lu Song et al. MEDIATORS OF INFLAMMATION
- The TNF-family cytokine TL1A promotes allergic immunopathology through group 2 innate lymphoid cells
- (2013) F Meylan et al. Mucosal Immunology
- TNF superfamily member TL1A elicits type 2 innate lymphoid cells at mucosal barriers
- (2013) X Yu et al. Mucosal Immunology
- Systematic identification of trans eQTLs as putative drivers of known disease associations
- (2013) Harm-Jan Westra et al. NATURE GENETICS
- A Genome-Wide Association Study Identifies 2 Susceptibility Loci for Crohn's Disease in a Japanese Population
- (2012) Keiko Yamazaki et al. GASTROENTEROLOGY
- TL1A/TNFSF15 directly induces proinflammatory cytokines, including TNFα, from CD3+CD161+ T cells to exacerbate gut inflammation
- (2012) S Jin et al. Mucosal Immunology
- Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease
- (2012) Luke Jostins et al. NATURE
- Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles
- (2012) Benjamin P Fairfax et al. NATURE GENETICS
- ENCODE Data in the UCSC Genome Browser: year 5 update
- (2012) Kate R. Rosenbloom et al. NUCLEIC ACIDS RESEARCH
- Differential expression of the TL1A/DcR3 system of TNF/TNFR-like proteins in large vs. small intestinal Crohn's disease
- (2011) Giorgos Bamias et al. DIGESTIVE AND LIVER DISEASE
- Triggering of TNFRSF25 promotes CD8+ T-cell responses and anti-tumor immunity
- (2011) Tomasz J. Slebioda et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- HLA-Cw*1202-B*5201-DRB1*1502 Haplotype Increases Risk for Ulcerative Colitis but Reduces Risk for Crohn's Disease
- (2011) Yukinori Okada et al. GASTROENTEROLOGY
- Association of TNFSF15 polymorphism with irritable bowel syndrome
- (2011) M. Zucchelli et al. GUT
- Opposing consequences of IL-23 signaling mediated by innate and adaptive cells in chemically induced colitis in mice
- (2011) J H Cox et al. Mucosal Immunology
- The IL23R R381Q Gene Variant Protects against Immune-Mediated Diseases by Impairing IL-23-Induced Th17 Effector Response in Humans
- (2011) Paola Di Meglio et al. PLoS One
- Functional Studies on the IBD Susceptibility Gene IL23R Implicate Reduced Receptor Function in the Protective Genetic Variant R381Q
- (2011) Svetlana Pidasheva et al. PLoS One
- Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses
- (2011) R. Sarin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A framework for oligonucleotide microarray preprocessing
- (2010) Benilton S. Carvalho et al. BIOINFORMATICS
- High intestinal and systemic levels of decoy receptor 3 (DcR3) and its ligand TL1A in active ulcerative colitis
- (2010) Giorgos Bamias et al. CLINICAL IMMUNOLOGY
- The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation
- (2010) F Meylan et al. Mucosal Immunology
- Genetics and Beyond – The Transcriptome of Human Monocytes and Disease Susceptibility
- (2010) Tanja Zeller et al. PLoS One
- A Bayesian Framework to Account for Complex Non-Genetic Factors in Gene Expression Levels Greatly Increases Power in eQTL Studies
- (2010) Oliver Stegle et al. PLoS Computational Biology
- Data structures and algorithms for analysis of genetics of gene expression with Bioconductor: GGtools 3.x
- (2009) V. J. Carey et al. BIOINFORMATICS
- Microbial induction of inflammatory bowel disease associated gene TL1A (TNFSF15) in antigen presenting cells
- (2009) David Q. Shih et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- TNFSF15 transcripts from risk haplotype for Crohn's disease are overexpressed in stimulated T cells
- (2009) Yoichi Kakuta et al. HUMAN MOLECULAR GENETICS
- Intestinal Lamina Propria Dendritic Cell Subsets Have Different Origin and Functions
- (2009) Chen Varol et al. IMMUNITY
- Origin of the Lamina Propria Dendritic Cell Network
- (2009) Milena Bogunovic et al. IMMUNITY
- NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
- (2009) Rachel Cooney et al. NATURE MEDICINE
- IBD-Associated TL1A Gene (TNFSF15) Haplotypes Determine Increased Expression of TL1A Protein
- (2009) Kathrin S. Michelsen et al. PLoS One
- TL1A (TNFSF15) Regulates the Development of Chronic Colitis by Modulating Both T-Helper 1 and T-Helper 17 Activation
- (2008) Hidetoshi Takedatsu et al. GASTROENTEROLOGY
- Innate and Adaptive Interleukin-22 Protects Mice from Inflammatory Bowel Disease
- (2008) Lauren A. Zenewicz et al. IMMUNITY
- The TNF-Family Receptor DR3 is Essential for Diverse T Cell-Mediated Inflammatory Diseases
- (2008) Françoise Meylan et al. IMMUNITY
- Essential role of TNF receptor superfamily 25 (TNFRSF25) in the development of allergic lung inflammation
- (2008) Lei Fang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Death Receptor 3–TNF-like protein 1A pathway drives adverse bone pathology in inflammatory arthritis
- (2008) Melanie Jane Bull et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TL1A–DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease
- (2008) Bhanu P. Pappu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
- (2008) Ken Cadwell et al. NATURE
- Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
- (2008) Yan Zheng et al. NATURE MEDICINE
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