Functional Studies on the IBD Susceptibility Gene IL23R Implicate Reduced Receptor Function in the Protective Genetic Variant R381Q
Published 2011 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Functional Studies on the IBD Susceptibility Gene IL23R Implicate Reduced Receptor Function in the Protective Genetic Variant R381Q
Authors
Keywords
-
Journal
PLoS One
Volume 6, Issue 10, Pages e25038
Publisher
Public Library of Science (PLoS)
Online
2011-10-13
DOI
10.1371/journal.pone.0025038
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The IL23R R381Q Gene Variant Protects against Immune-Mediated Diseases by Impairing IL-23-Induced Th17 Effector Response in Humans
- (2011) Paola Di Meglio et al. PLoS One
- Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses
- (2011) R. Sarin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease
- (2010) Yukihide Momozawa et al. NATURE GENETICS
- Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
- (2010) Andre Franke et al. NATURE GENETICS
- Genetic Variants in IL-23R and ATG16L1 Independently Predispose to Increased Susceptibility to Crohnʼs Disease in a Canadian Population
- (2009) William G. Newman et al. JOURNAL OF CLINICAL GASTROENTEROLOGY
- Th17 cells at the crossroads of innate and adaptive immunity against infectious diseases at the mucosa
- (2009) S A Khader et al. Mucosal Immunology
- Ulcerative colitis–risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study
- (2009) Mark S Silverberg et al. NATURE GENETICS
- Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells
- (2009) Sara Trifari et al. NATURE IMMUNOLOGY
- The IL23R Arg381Gln non-synonymous polymorphism confers susceptibility to ankylosing spondylitis
- (2008) B Rueda et al. ANNALS OF THE RHEUMATIC DISEASES
- A Randomized Trial of Ustekinumab, a Human Interleukin-12/23 Monoclonal Antibody, in Patients With Moderate-to-Severe Crohn's Disease
- (2008) William J. Sandborn et al. GASTROENTEROLOGY
- The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation
- (2008) Wenjun Ouyang et al. IMMUNITY
- New mutations of MPL in primitive myelofibrosis: only the MPL W515 mutations promote a G1/S-phase transition
- (2008) R Chaligné et al. LEUKEMIA
- Impaired Autophagy of an Intracellular Pathogen Induced by a Crohn's Disease Associated ATG16L1 Variant
- (2008) Petric Kuballa et al. PLoS One
- Contribution of positively charged flanking residues to the insertion of transmembrane helices into the endoplasmic reticulum
- (2008) M. Lerch-Bader et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genetic Mapping in Human Disease
- (2008) D. Altshuler et al. SCIENCE
- Linking genetic susceptibility to Crohnʼs disease with Th17 cell function: IL-22 serum levels are increased in Crohnʼs disease and correlate with disease activity and IL23R genotype status
- (2007) Silke Schmechel et al. INFLAMMATORY BOWEL DISEASES
- Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): Upregulated colonic IL-17F expression in active Crohnʼs disease and analysis of the IL17F p.His161Arg polymorphism in IBD
- (2007) Julia Seiderer et al. INFLAMMATORY BOWEL DISEASES
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started