Predictors of Hepatitis B Cure Using Gene Therapy to Deliver DNA Cleavage Enzymes: A Mathematical Modeling Approach

Targeted gene disruption to cure HIV

(2013) Daniel Stone et al.   Current Opinion in HIV and AIDS

HIV Latency

(2013) R. F. Siliciano et al.   Cold Spring Harbor Perspectives in Medicine

Novel Cell and Gene Therapies for HIV

(2013) J. A. Hoxie et al.   Cold Spring Harbor Perspectives in Medicine

Hematopoietic-Stem-Cell-Based Gene Therapy for HIV Disease

(2012) Hans-Peter Kiem et al.   Cell Stem Cell

Intracellular transport of recombinant adeno-associated virus vectors

(2012) M Nonnenmacher et al.   GENE THERAPY

A Quantitative Measurement of Antiviral Activity of Anti-Human Immunodeficiency Virus Type 1 Drugs against Simian Immunodeficiency Virus Infection: Dose-Response Curve Slope Strongly Influences Class-Specific Inhibitory Potential

(2012) K. Deng et al.   JOURNAL OF VIROLOGY

Targeted DNA Mutagenesis for the Cure of Chronic Viral Infections

(2012) J. T. Schiffer et al.   JOURNAL OF VIROLOGY

A quantitative basis for antiretroviral therapy for HIV-1 infection

(2012) Benjamin L Jilek et al.   NATURE MEDICINE

Virological breakthrough and resistance in patients with chronic hepatitis B receiving nucleos(t)ide analogues in clinical practice

(2011) Chanunta Hongthanakorn et al.   HEPATOLOGY

Impact of Pre-Existing Immunity on Gene Transfer to Nonhuman Primate Liver with Adeno-Associated Virus 8 Vectors

(2011) Lili Wang et al.   HUMAN GENE THERAPY

Detailed analysis of mucosal herpes simplex virus-2 replication kinetics with and without antiviral therapy

(2011) J. T. Schiffer et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

TerminalN-Linked Galactose Is the Primary Receptor for Adeno-associated Virus 9

(2011) Shen Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutralizing Antibodies Against AAV Serotypes 1, 2, 6, and 9 in Sera of Commonly Used Animal Models

(2011) Kleopatra Rapti et al.   MOLECULAR THERAPY

Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B

(2011) Amit C. Nathwani et al.   NEW ENGLAND JOURNAL OF MEDICINE

Successful Targeting and Disruption of an Integrated Reporter Lentivirus Using the Engineered Homing Endonuclease Y2 I-AniI

(2011) Martine Aubert et al.   PLoS One

Dose-response curve slope is a missing dimension in the analysis of HIV-1 drug resistance

(2011) M. E. S. Sampah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Critical Subset Model Provides a Conceptual Basis for the High Antiviral Activity of Major HIV Drugs

(2011) L. Shen et al.   Science Translational Medicine

Engineering HIV-Resistant Human CD4+ T Cells with CXCR4-Specific Zinc-Finger Nucleases

(2011) Craig B. Wilen et al.   PLoS Pathogens

Molecular genetics of HBV infection

(2010) Stephen Locarnini et al.   ANTIVIRAL THERAPY

Detection of Hepatitis B and C Viruses in Almost All Hepatocytes by Modified PCR-Based In Situ Hybridization

(2010) H. Nuriya et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Zinc-finger Nucleases as a Novel Therapeutic Strategy for Targeting Hepatitis B Virus DNAs

(2010) Thomas J Cradick et al.   MOLECULAR THERAPY

Preexisting Immunity and Low Expression in Primates Highlight Translational Challenges for Liver-directed AAV8-mediated Gene Therapy

(2010) Gregory D Hurlbut et al.   MOLECULAR THERAPY

HIV Persistence and the Prospect of Long-Term Drug-Free Remissions for HIV-Infected Individuals

(2010) D. Trono et al.   SCIENCE

Novel Viral Vector Systems for Gene Therapy

(2010) Daniel Stone   Viruses-Basel

Generation of Covalently Closed Circular DNA of Hepatitis B Viruses via Intracellular Recycling Is Regulated in a Virus Specific Manner

(2010) Josef Köck et al.   PLoS Pathogens

Increased mutations in Env and Pol suggest greater HIV-1 replication in sputum-derived viruses compared with blood-derived viruses

(2009) Thor A Wagner et al.   AIDS

A novel method for determining the inhibitory potential of anti-HIV drugs

(2009) Lin Shen et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Adenovirus Serotype 5 Hexon Mediates Liver Gene Transfer

(2008) Simon N. Waddington et al.   CELL

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

(2008) Elena E Perez et al.   NATURE BIOTECHNOLOGY

Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs

(2008) Lin Shen et al.   NATURE MEDICINE

Adenovirus serotype 5 hexon is critical for virus infection of hepatocytes in vivo

(2008) O. Kalyuzhniy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA