Successful Targeting and Disruption of an Integrated Reporter Lentivirus Using the Engineered Homing Endonuclease Y2 I-AniI

B cell-specific lentiviral gene therapy leads to sustained B-cell functional recovery in a murine model of X-linked agammaglobulinemia

(2010) H. M. Kerns et al.   BLOOD

Zinc-finger Nucleases as a Novel Therapeutic Strategy for Targeting Hepatitis B Virus DNAs

(2010) Thomas J Cradick et al.   MOLECULAR THERAPY

Homing endonucleases: from basics to therapeutic applications

(2009) Maria J. Marcaida et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Targeted approaches for gene therapy and the emergence of engineered meganucleases

(2009) Roman Galetto et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Exploitation of binding energy for catalysis and design

(2009) Summer B. Thyme et al.   NATURE

Motif-directed flexible backbone design of functional interactions

(2009) James J. Havranek et al.   PROTEIN SCIENCE

Computer design of obligate heterodimer meganucleases allows efficient cutting of custom DNA sequences

(2008) Emmanuel Fajardo-Sanchez et al.   NUCLEIC ACIDS RESEARCH

Optimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degradation

(2008) Ryo Takeuchi et al.   NUCLEIC ACIDS RESEARCH