USP11 augments TGF  signalling by deubiquitylating ALK5

USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma

(2012) Pieter J A Eichhorn et al.   NATURE MEDICINE

Regulation of the transforming growth factor   pathway by reversible ubiquitylation

(2012) M. A. Al-Salihi et al.   Open Biology

How ubiquitination regulates the TGF-β signalling pathway: New insights and new players

(2011) Surinder M. Soond et al.   BIOESSAYS

SNX25 regulates TGF-β signaling by enhancing the receptor degradation

(2011) Xinbao Hao et al.   CELLULAR SIGNALLING

The specificities of small molecule inhibitors of the TGFß and BMP pathways

(2011) Janis Vogt et al.   CELLULAR SIGNALLING

TGF-β/TGF-β receptor system and its role in physiological and pathological conditions

(2011) Juan F. Santibañez et al.   CLINICAL SCIENCE

The Deubiquitinase CYLD Targets Smad7 Protein to Regulate Transforming Growth Factor β (TGF-β) Signaling and the Development of Regulatory T Cells

(2011) Yongge Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

USP15 is a deubiquitylating enzyme for receptor-activated SMADs

(2011) Masafumi Inui et al.   NATURE CELL BIOLOGY

Stem cell antigen-1 enhances tumorigenicity by disruption of growth differentiation factor-10 (GDF10)-dependent TGF-  signaling

(2011) G. Upadhyay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Smad7 and Smad6 bind to discrete regions of Pellino-1 via their MH2 domains to mediate TGF-β1-induced negative regulation of IL-1R/TLR signaling

(2010) Youn Sook Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

AACR Special Conference on Epithelial-Mesenchymal Transition and Cancer Progression and Treatment

(2010) E. T. Roussos et al.   CANCER RESEARCH

Ubiquitination and deubiquitination of NP protein regulates influenza A virus RNA replication

(2010) Tsai-Ling Liao et al.   EMBO JOURNAL

Sensitivity to Poly(ADP-ribose) Polymerase (PARP) Inhibition Identifies Ubiquitin-specific Peptidase 11 (USP11) as a Regulator of DNA Double-strand Break Repair

(2010) Timothy D. Wiltshire et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of TGF-  signaling by Smad7

(2009) X. Yan et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

FAM/USP9x, a Deubiquitinating Enzyme Essential for TGFβ Signaling, Controls Smad4 Monoubiquitination

(2009) Sirio Dupont et al.   CELL

USP11 negatively regulates TNFα-induced NF-κB activation by targeting on IκBα

(2009) Wenjing Sun et al.   CELLULAR SIGNALLING

Ubiquitin Ligase Nedd4L Targets Activated Smad2/3 to Limit TGF-β Signaling

(2009) Sheng Gao et al.   MOLECULAR CELL

The morphological and molecular features of the epithelial-to-mesenchymal transition

(2009) Gema Moreno-Bueno et al.   Nature Protocols

Breaking the chains: structure and function of the deubiquitinases

(2009) David Komander et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The HECT Family of E3 Ubiquitin Ligases: Multiple Players in Cancer Development

(2008) Francesca Bernassola et al.   CANCER CELL

TGFβ in Cancer

(2008) Joan Massagué   CELL

TGFβ-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFβ switch

(2008) Irwin M Liu et al.   EMBO JOURNAL

USP11 Stabilizes HPV-16E7 and Further Modulates the E7 Biological Activity

(2008) Ching-Hui Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Smad7 Stabilizes β-Catenin Binding to E-cadherin Complex and Promotes Cell-Cell Adhesion

(2008) Yi Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY