TGF-β/TGF-β receptor system and its role in physiological and pathological conditions

The TGF-β co-receptor, CD109, promotes internalization and degradation of TGF-β receptors

(2011) Albane A. Bizet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Transforming growth factor-beta 2 gene silencing with trabedersen (AP 12009) in pancreatic cancer

(2011) Karl-Hermann Schlingensiepen et al.   CANCER SCIENCE

TGF-β and Restenosis Revisited: A Smad Link

(2011) Pasithorn A. Suwanabol et al.   JOURNAL OF SURGICAL RESEARCH

The Role of the TGF-β Coreceptor Endoglin in Cancer

(2011) Eduardo Pérez-Gómez et al.   TheScientificWorldJOURNAL

Overlapping spectra ofSMAD4mutations in juvenile polyposis (JP) and JP-HHT syndrome

(2010) Carol Gallione et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

The physiological role of endoglin in the cardiovascular system

(2010) José M. López-Novoa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Bone morphogenetic protein and growth differentiation factor cytokine families and their protein antagonists

(2010) Christopher C. Rider et al.   BIOCHEMICAL JOURNAL

Hereditary haemorrhagic telangiectasia: Pathophysiology, diagnosis and treatment

(2010) Claire L. Shovlin   BLOOD REVIEWS

Identification of a novel transforming growth factor-beta (TGF-beta6) gene in fish: regulation in skeletal muscle by nutritional state

(2010) Bruria Funkenstein et al.   BMC MOLECULAR BIOLOGY

Neuropilin-1 exerts co-receptor function for TGF-beta-1 on the membrane of cancer cells and enhances responses to both latent and active TGF-beta

(2010) Yelena Glinka et al.   CARCINOGENESIS

Roles for the type III TGF-β receptor in human cancer

(2010) Catherine E. Gatza et al.   CELLULAR SIGNALLING

Potential Therapeutic Targets for Cardiac Fibrosis

(2010) Andrew Leask   CIRCULATION RESEARCH

Inhibition of Bone Morphogenetic Proteins Protects Against Atherosclerosis and Vascular Calcification

(2010) Yucheng Yao et al.   CIRCULATION RESEARCH

Bone morphogenetic protein 7 (BMP7) mutations are associated with variable ocular, brain, ear, palate, and skeletal anomalies

(2010) Alexander W. Wyatt et al.   HUMAN MUTATION

Variants of the BMP15 gene in a cohort of patients with premature ovarian failure

(2010) D. Tiotiu et al.   HUMAN REPRODUCTION

Administration of a soluble activin type IIB receptor promotes skeletal muscle growth independent of fiber type

(2010) Samuel M. Cadena et al.   JOURNAL OF APPLIED PHYSIOLOGY

The ovary: basic biology and clinical implications

(2010) JoAnne S. Richards et al.   JOURNAL OF CLINICAL INVESTIGATION

Integral role of GDF-9 and BMP-15 in ovarian function

(2010) Fumio Otsuka et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Targeted therapy for high-grade glioma with the TGF- 2 inhibitor trabedersen: results of a randomized and controlled phase IIb study

(2010) U. Bogdahn et al.   NEURO-ONCOLOGY

Signaling by members of the TGF-β family in vascular morphogenesis and disease

(2010) Evangelia Pardali et al.   TRENDS IN CELL BIOLOGY

Paclitaxel ameliorates fibrosis in hepatic stellate cellsviainhibition of TGF-β/Smad activity

(2010) Jun Zhou   WORLD JOURNAL OF GASTROENTEROLOGY

Endoglin-Targeted Cancer Therapy

(2010) Ben K. Seon et al.   Current Drug Delivery

The pathogenesis of idiopathic pulmonary fibrosis

(2010) William R. Coward et al.   Therapeutic Advances in Respiratory Disease

TGF-β Superfamily Receptors—Targets for Antiangiogenic Therapy?

(2010) Jasmin Otten et al.   Journal of Oncology

The emerging role of TGF-β superfamily coreceptors in cancer

(2009) Carmelo Bernabeu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

TGF-β and fibrosis in different organs — molecular pathway imprints

(2009) Dirk Pohlers et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Emergence, development and diversification of the TGF-β signalling pathway within the animal kingdom

(2009) Lukasz Huminiecki et al.   BMC EVOLUTIONARY BIOLOGY

The RGM/DRAGON family of BMP co-receptors

(2009) Elena Corradini et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Transforming growth factor beta (TGF-β) and inflammation in cancer

(2009) Brian Bierie et al.   CYTOKINE & GROWTH FACTOR REVIEWS

The regulation of TGF  signal transduction

(2009) A. Moustakas et al.   DEVELOPMENT

Incomplete penetrance and phenotypic variability characterize Gdf6-attributable oculo-skeletal phenotypes

(2009) M. Asai-Coakwell et al.   HUMAN MOLECULAR GENETICS

Mutation of the bone morphogenetic protein GDF3 causes ocular and skeletal anomalies

(2009) M. Ye et al.   HUMAN MOLECULAR GENETICS

Inhibin and premature ovarian failure

(2009) A.L. Chand et al.   HUMAN REPRODUCTION UPDATE

Bone morphogenetic protein receptors and signal transduction

(2009) K. Miyazono et al.   JOURNAL OF BIOCHEMISTRY

The biology of activin: recent advances in structure, regulation and function

(2009) Yin Xia et al.   JOURNAL OF ENDOCRINOLOGY

Transforming Growth Factor β–Induced Endothelial-to-Mesenchymal Transition: A Switch to Cardiac Fibrosis?

(2009) Marie-José Goumans et al.   TRENDS IN CARDIOVASCULAR MEDICINE

New regulatory mechanisms of TGF-β receptor function

(2009) Jong Seok Kang et al.   TRENDS IN CELL BIOLOGY

Inhibins: from reproductive hormones to tumor suppressors

(2009) Kaye L. Stenvers et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Nodal Morphogens

(2009) A. F. Schier   Cold Spring Harbor Perspectives in Biology

Compound heterozygosity for GDF5 in Du Pan type chondrodysplasia

(2008) Sofia Douzgou et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Hepatocyte Growth Factor Inhibits Epithelial to Myofibroblast Transition in Lung Cells via Smad7

(2008) Manasi N. Shukla et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Role of transforming growth factor-β superfamily signaling pathways in human disease

(2008) Kelly J. Gordon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

TGFβ in Cancer

(2008) Joan Massagué   CELL

TGF-β signaling in vascular biology and dysfunction

(2008) Marie-José Goumans et al.   CELL RESEARCH

Non-Smad pathways in TGF-β signaling

(2008) Ying E Zhang   CELL RESEARCH

Recent advances in colorectal cancer genetics and diagnostics

(2008) Peh Yean Cheah   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Antitransforming growth factor-β therapy in fibrosis: recent progress and implications for systemic sclerosis

(2008) John Varga et al.   CURRENT OPINION IN RHEUMATOLOGY

Mutational analysis of the ACVR1 gene in Italian patients affected with fibrodysplasia ossificans progressiva: confirmations and advancements

(2008) Renata Bocciardi et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Mutations in GDF6 are associated with vertebral segmentation defects in Klippel-Feil syndrome

(2008) May Tassabehji et al.   HUMAN MUTATION

Autoimmune Hemolytic Anemia Associated With Ovarian Cancer

(2008) Patrick G. Morris et al.   JOURNAL OF CLINICAL ONCOLOGY

Novel point mutations in GDF5 associated with two distinct limb malformations in Chinese: brachydactyly type C and proximal symphalangism

(2008) Wei Yang et al.   JOURNAL OF HUMAN GENETICS

BMP type I receptor inhibition reduces heterotopic ossification

(2008) Paul B Yu et al.   NATURE MEDICINE

New insights into the mechanisms of fibrosis and sclerosis in diabetic nephropathy

(2008) Frank C. Brosius   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

How the Smads regulate transcription

(2007) Sarah Ross et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY