SIRT1 overexpression ameliorates a mouse model of SOD1-linked amyotrophic lateral sclerosis via HSF1/HSP70i chaperone system
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Title
SIRT1 overexpression ameliorates a mouse model of SOD1-linked amyotrophic lateral sclerosis via HSF1/HSP70i chaperone system
Authors
Keywords
Sirtuin 1 (SIRT1), Cu/Zn-superoxide dismutase (SOD1), Heat shock factor 1 (HSF1), Heat shock protein (HSP), Amyotrophic lateral sclerosis (ALS), Systematic behavioral screening
Journal
Molecular Brain
Volume 7, Issue 1, Pages -
Publisher
Springer Nature
Online
2014-08-28
DOI
10.1186/s13041-014-0062-1
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- (2012) S. Guareschi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cross-functional E3 ligases Parkin and C-terminus Hsp70-interacting protein in neurodegenerative disorders
- (2011) Pravir Kumar et al. JOURNAL OF NEUROCHEMISTRY
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- Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis
- (2011) Laura Ferraiuolo et al. Nature Reviews Neurology
- Protective Role of Heat Shock Proteins in Parkinson’s Disease
- (2011) Paolo Aridon et al. Neurodegenerative Diseases
- Overexpression of SIRT1 in Mouse Forebrain Impairs Lipid/Glucose Metabolism and Motor Function
- (2011) Dongmei Wu et al. PLoS One
- RETRACTED: SIRT1 Suppresses β-Amyloid Production by Activating the α-Secretase Gene ADAM10
- (2010) Gizem Donmez et al. CELL
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- (2009) Kenichi Kakefuda et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Ubiquitin Ligase E6-AP Is Induced and Recruited to Aggresomes in Response to Proteasome Inhibition and May Be Involved in the Ubiquitination of Hsp70-bound Misfolded Proteins
- (2009) Amit Mishra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1
- (2009) S. D. Westerheide et al. SCIENCE
- Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis†
- (2008) Cristina Cheroni et al. HUMAN MOLECULAR GENETICS
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