PDCD10 (CCM3) regulates brain endothelial barrier integrity in cerebral cavernous malformation type 3: role of CCM3-ERK1/2-cortactin cross-talk
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
PDCD10 (CCM3) regulates brain endothelial barrier integrity in cerebral cavernous malformation type 3: role of CCM3-ERK1/2-cortactin cross-talk
Authors
Keywords
CCM3, Tight junction, Cortactin, Brain endothelial barrier, Permeability
Journal
ACTA NEUROPATHOLOGICA
Volume 130, Issue 5, Pages 731-750
Publisher
Springer Nature
Online
2015-09-18
DOI
10.1007/s00401-015-1479-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Highly variable intrafamilial manifestations of a CCM3 mutation ranging from acute childhood cerebral haemorrhage to late-onset meningiomas
- (2015) C. Fauth et al. CLINICAL NEUROLOGY AND NEUROSURGERY
- CCM2–CCM3 interaction stabilizes their protein expression and permits endothelial network formation
- (2015) Kyle M. Draheim et al. JOURNAL OF CELL BIOLOGY
- Quantitative Analysis of Histological Staining and Fluorescence Using ImageJ
- (2014) Ellen C. Jensen Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
- Cortactin Scaffolds Arp2/3 and WAVE2 at the Epithelial Zonula Adherens
- (2014) Siew Ping Han et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bleeding propensity of cavernous malformations: impact of tight junction alterations on the occurrence of overt hematoma
- (2014) Dejan Jakimovski et al. JOURNAL OF NEUROSURGERY
- Inhibition of junctional adhesion molecule-A/LFA interaction attenuates leukocyte trafficking and inflammation in brain ischemia/reperfusion injury
- (2014) Nikola Sladojevic et al. NEUROBIOLOGY OF DISEASE
- Architecture of tight junctions and principles of molecular composition
- (2014) Christina M. Van Itallie et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- The role of actin-binding proteins in the control of endothelial barrier integrity
- (2014) A. García-Ponce et al. THROMBOSIS AND HAEMOSTASIS
- SOcK, MiSTs, MASK and STicKs: the GCKIII (germinal centre kinase III) kinases and their heterologous protein–protein interactions
- (2013) Peter H. Sugden et al. BIOCHEMICAL JOURNAL
- STRIPAK complexes: Structure, biological function, and involvement in human diseases
- (2013) Juyeon Hwang et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Interaction of p190RhoGAP with C-terminal Domain of p120-catenin Modulates Endothelial Cytoskeleton and Permeability
- (2013) Noureddine Zebda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- EndMT contributes to the onset and progression of cerebral cavernous malformations
- (2013) Luigi Maddaluno et al. NATURE
- Dynamic Permeability and Quantitative Susceptibility
- (2013) Abdul Ghani Mikati et al. STROKE
- Consecutive Proteolytic Digestion in an Enzyme Reactor Increases Depth of Proteomic and Phosphoproteomic Analysis
- (2012) Jacek R. Wiśniewski et al. ANALYTICAL CHEMISTRY
- Ultrastructural analysis of vascular features in cerebral cavernous malformations
- (2012) Gamze Tanriover et al. CLINICAL NEUROLOGY AND NEUROSURGERY
- The outlook for adults with epileptic seizure(s) associated with cerebral cavernous malformations or arteriovenous malformations
- (2012) Rustam Al-Shahi Salman EPILEPSIA
- Extracellular Signal-regulated Kinase (ERK) Regulates Cortactin Ubiquitination and Degradation in Lung Epithelial Cells
- (2012) Jing Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Antithrombotic Therapy and Bleeding Risk in a Prospective Cohort Study of Patients With Cerebral Cavernous Malformations
- (2012) Hans-Martin Schneble et al. STROKE
- Tyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motility
- (2011) Wenqi Wang et al. BMC CELL BIOLOGY
- Ccm3 functions in a manner distinct from Ccm1 and Ccm2 in a zebrafish model of CCM vascular disease
- (2011) Bilge Yoruk et al. DEVELOPMENTAL BIOLOGY
- Structure-Function Analysis of Core STRIPAK Proteins
- (2011) Michelle J. Kean et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cortactin deficiency is associated with reduced neutrophil recruitment but increased vascular permeability in vivo
- (2011) Michael Schnoor et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Impairment of Tight Junctions and Glucose Transport in Endothelial Cells of Human Cerebral Cavernous Malformations
- (2011) Hannah Schneider et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Editorial
- (2011) Issam A. Awad JOURNAL OF NEUROSURGERY
- Loss ofcerebral cavernous malformation 3(Ccm3) in neuroglia leads to CCM and vascular pathology
- (2011) Angeliki Louvi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Zona occludens proteins modulate podosome formation and function
- (2010) Joachim Kremerskothen et al. FASEB JOURNAL
- Recent insights into cerebral cavernous malformations: the molecular genetics of CCM
- (2010) Florence Riant et al. FEBS Journal
- A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease
- (2010) D. A. McDonald et al. HUMAN MOLECULAR GENETICS
- Rho Kinase Inhibition Rescues the Endothelial Cell Cerebral Cavernous Malformation Phenotype
- (2010) Asya L. Borikova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CCM1 regulates vascular-lumen organization by inducing endothelial polarity
- (2010) M. G. Lampugnani et al. JOURNAL OF CELL SCIENCE
- Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity
- (2010) Rebecca A. Stockton et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Magnetic Resonance Imaging Evaluation of Cerebral Cavernous Malformations With Susceptibility-Weighted Imaging
- (2010) Nicolas Menjot de Champfleur et al. NEUROSURGERY
- The pathogenetic features of cerebral cavernous malformations: a comprehensive review with therapeutic implications
- (2010) Khaled M. Krisht et al. Neurosurgical Focus
- Cerebral cavernous malformations as a disease of vascular permeability: from bench to bedside with caution
- (2010) Sanjay Yadla et al. Neurosurgical Focus
- Upregulation of transmembrane endothelial junction proteins in human cerebral cavernous malformations
- (2010) Jan-Karl Burkhardt et al. Neurosurgical Focus
- Defining the Functional Domain of Programmed Cell Death 10 through Its Interactions with Phosphatidylinositol-3,4,5-Trisphosphate
- (2010) Christopher F. Dibble et al. PLoS One
- Cortactin Phosphorylated by ERK1/2 Localizes to Sites of Dynamic Actin Regulation and Is Required for Carcinoma Lamellipodia Persistence
- (2010) Laura C. Kelley et al. PLoS One
- Stabilization of VEGFR2 Signaling by Cerebral Cavernous Malformation 3 Is Critical for Vascular Development
- (2010) Y. He et al. Science Signaling
- Zonula Occludens-1 and -2 Are Cytosolic Scaffolds That Regulate the Assembly of Cellular Junctions
- (2009) Alan S. Fanning et al. Annals of the New York Academy of Sciences
- Caveolae-mediated Internalization of Occludin and Claudin-5 during CCL2-induced Tight Junction Remodeling in Brain Endothelial Cells
- (2009) Svetlana M. Stamatovic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cortactin: Coordinating adhesion and the actin cytoskeleton at cellular protrusions
- (2009) Gang Ren et al. CELL MOTILITY AND THE CYTOSKELETON
- Regulation of Endothelial Junctional Permeability
- (2008) Emily Vandenbroucke et al. Annals of the New York Academy of Sciences
- Brain Endothelial Cell-Cell Junctions: How to “Open” the Blood Brain Barrier
- (2008) Svetlana Stamatovic et al. Current Neuropharmacology
- Novel CCM1, CCM2, and CCM3 mutations in patients with cerebral cavernous malformations: in-frame deletion in CCM2 prevents formation of a CCM1/CCM2/CCM3 protein complex
- (2008) Sonja Stahl et al. HUMAN MUTATION
- ADVANCED MAGNETIC RESONANCE IMAGING OF CEREBRAL CAVERNOUS MALFORMATIONS
- (2008) Robert Shenkar et al. NEUROSURGERY
- Structural organization of the tight junctions
- (2007) Luca Paris et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Cerebral cavernous malformations: congruency of histopathological features with the current clinical definition
- (2007) J M Frischer et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now