CCM2–CCM3 interaction stabilizes their protein expression and permits endothelial network formation

How to find a leucine in a haystack? Structure, ligand recognition and regulation of leucine–aspartic acid (LD) motifs

(2014) Tanvir Alam et al.   BIOCHEMICAL JOURNAL

Structural Basis for the Disruption of the Cerebral Cavernous Malformations 2 (CCM2) Interaction with Krev Interaction Trapped 1 (KRIT1) by Disease-associated Mutations

(2014) Oriana S. Fisher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cerebral cavernous malformation proteins at a glance

(2014) Kyle M. Draheim et al.   JOURNAL OF CELL SCIENCE

SOcK, MiSTs, MASK and STicKs: the GCKIII (germinal centre kinase III) kinases and their heterologous protein–protein interactions

(2013) Peter H. Sugden et al.   BIOCHEMICAL JOURNAL

Signaling pathways and the cerebral cavernous malformations proteins: lessons from structural biology

(2013) Oriana S. Fisher et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

CCM1–ICAP-1 complex controls β1 integrin–dependent endothelial contractility and fibronectin remodeling

(2013) Eva Faurobert et al.   JOURNAL OF CELL BIOLOGY

Dynamic Regulation of the Cerebral Cavernous Malformation Pathway Controls Vascular Stability and Growth

(2012) Xiangjian Zheng et al.   DEVELOPMENTAL CELL

Structural studies of cerebral cavernous malformations 2 (CCM2) reveal a folded helical domain at its C-terminus

(2012) Oriana S. Fisher et al.   FEBS LETTERS

Adaptor Protein Cerebral Cavernous Malformation 3 (CCM3) Mediates Phosphorylation of the Cytoskeletal Proteins Ezrin/Radixin/Moesin by Mammalian Ste20-4 to Protect Cells from Oxidative Stress

(2012) Miguel Fidalgo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Presenting your structures: theCCP4mgmolecular-graphics software

(2011) S. McNicholas et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Protein phosphatase 2a (PP2A) binds within the oligomerization domain of striatin and regulates the phosphorylation and activation of the mammalian Ste20-Like kinase Mst3

(2011) Johnthan Gordon et al.   BMC BIOCHEMISTRY

Molecular Recognition of Leucine-Aspartate Repeat (LD) Motifs by the Focal Adhesion Targeting Homology Domain of Cerebral Cavernous Malformation 3 (CCM3)

(2011) Xiaofeng Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure-Function Analysis of Core STRIPAK Proteins

(2011) Michelle J. Kean et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Recent insights into cerebral cavernous malformations: animal models of CCM and the human phenotype

(2010) Aubrey C. Chan et al.   FEBS Journal

Crystal Structure of CCM3, a Cerebral Cavernous Malformation Protein Critical for Vascular Integrity

(2010) Xiaofeng Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rho Kinase Inhibition Rescues the Endothelial Cell Cerebral Cavernous Malformation Phenotype

(2010) Asya L. Borikova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cerebral cavernous malformation protein CCM1 inhibits sprouting angiogenesis by activating DELTA-NOTCH signaling

(2010) Joycelyn Wüstehube et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ALINE: a WYSIWYG protein-sequence alignment editor for publication-quality alignments

(2009) Charles Simon Bond et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2

(2009) James Lulo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

ccm1 cell autonomously regulates endothelial cellular morphogenesis and vascular tubulogenesis in zebrafish

(2008) Benjamin M. Hogan et al.   HUMAN MOLECULAR GENETICS

A PP2A Phosphatase High Density Interaction Network Identifies a Novel Striatin-interacting Phosphatase and Kinase Complex Linked to the Cerebral Cavernous Malformation 3 (CCM3) Protein

(2008) Marilyn Goudreault et al.   MOLECULAR & CELLULAR PROTEOMICS

Rapid one-step recombinational cloning

(2008) C. Fu et al.   NUCLEIC ACIDS RESEARCH