Microbial modulation of the gut microbiome for treating autoimmune diseases

The Impact of Dietary Fiber on Gut Microbiota in Host Health and Disease

(2018) Kassem Makki et al.   Cell Host & Microbe

Translocation of a gut pathobiont drives autoimmunity in mice and humans

(2018) S. Manfredo Vieira et al.   SCIENCE

Diet, Genetics, and the Gut Microbiome Drive Dynamic Changes in Plasma Metabolites

(2018) Shiho Fujisaka et al.   Cell Reports

Bacteroides fragilis Protects Against Antibiotic-Associated Diarrhea in Rats by Modulating Intestinal Defenses

(2018) Wendi Zhang et al.   Frontiers in Immunology

Efficacy of Sterile Fecal Filtrate Transfer for Treating Patients With Clostridium difficile Infection

(2017) Stephan J. Ott et al.   GASTROENTEROLOGY

Akkermansia muciniphilainduces gut microbiota remodelling and controls islet autoimmunity in NOD mice

(2017) Arno Hänninen et al.   GUT

Intestinal dysbiosis and probiotic applications in autoimmune diseases

(2017) Gislane Lelis Vilela de Oliveira et al.   IMMUNOLOGY

Gut microbes shape response to cancer immunotherapy

(2017) Jocelyn Kaiser   SCIENCE

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

(2017) Bertrand Routy et al.   SCIENCE

Human Gut-Derived Commensal Bacteria Suppress CNS Inflammatory and Demyelinating Disease

(2017) Ashutosh Mangalam et al.   Cell Reports

Dietary and Microbial Metabolites in the Regulation of Host Immunity

(2017) Naoko Shibata et al.   Frontiers in Microbiology

Emerging Trends in “Smart Probiotics”: Functional Consideration for the Development of Novel Health and Industrial Applications

(2017) Racha El Hage et al.   Frontiers in Microbiology

Functional Characterization of Novel Faecalibacterium prausnitzii Strains Isolated from Healthy Volunteers: A Step Forward in the Use of F. prausnitzii as a Next-Generation Probiotic

(2017) Rebeca Martín et al.   Frontiers in Microbiology

Safety of Novel Microbes for Human Consumption: Practical Examples of Assessment in the European Union

(2017) Theodor Brodmann et al.   Frontiers in Microbiology

Development of the gut microbiota in infancy and its impact on health in later life

(2017) Masaru Tanaka et al.   ALLERGOLOGY INTERNATIONAL

Evidence of the Immune Relevance of Prevotella copri , a Gut Microbe, in Patients With Rheumatoid Arthritis

(2017) Annalisa Pianta et al.   Arthritis & Rheumatology

Epstein–Barr virus and multiple sclerosis: Updating Pender's hypothesis

(2017) Martin Laurence et al.   Multiple Sclerosis and Related Disorders

Modulation of Gut Microbiota in Pathological States

(2017) Yulan Wang et al.   Engineering

Modulation of the human gut microbiota by dietary fibres occurs at the species level

(2016) Wing Sun Faith Chung et al.   BMC BIOLOGY

The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites

(2016) Gerard E. Kaiko et al.   CELL

Gut Microbiota Developments With Emphasis on Inflammatory Bowel Disease: Report From the Gut Microbiota for Health World Summit 2016

(2016) Hester Eppinga et al.   GASTROENTEROLOGY

Frozen vs Fresh Fecal Microbiota Transplantation and Clinical Resolution of Diarrhea in Patients With RecurrentClostridium difficileInfection

(2016) Christine H. Lee et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

(2016) Hubert Plovier et al.   NATURE MEDICINE

The Infant Microbiome

(2016) Irene Yang et al.   NURSING RESEARCH

An expansion of rare lineage intestinal microbes characterizes rheumatoid arthritis

(2016) Jun Chen et al.   Genome Medicine

Microbial metabolism of dietary components to bioactive metabolites: opportunities for new therapeutic interventions

(2016) Linda S. Zhang et al.   Genome Medicine

The effects of orally administered Bacillus coagulans and inulin on prevention and progression of rheumatoid arthritis in rats

(2016) Khadijeh Abhari et al.   Food & Nutrition Research

Oral Probiotic VSL#3 Prevents Autoimmune Diabetes by Modulating Microbiota and Promoting Indoleamine 2,3-Dioxygenase-Enriched Tolerogenic Intestinal Environment

(2016) Jayashree Dolpady et al.   Journal of Diabetes Research

Suppression of Inflammatory Arthritis by Human Gut-Derived Prevotella histicola in Humanized Mice

(2016) Eric V. Marietta et al.   Arthritis & Rheumatology

Novel perspectives on therapeutic modulation of the gut microbiota

(2016) Justin L. McCarville et al.   Therapeutic Advances in Gastroenterology

Fecal Microbiota Transplantation and Its Usage in Neuropsychiatric Disorders

(2016) Alper Evrensel et al.   Clinical Psychopharmacology and Neuroscience

Faecalibacterium prausnitzii A2-165 has a high capacity to induce IL-10 in human and murine dendritic cells and modulates T cell responses

(2016) Oriana Rossi et al.   Scientific Reports

Mutual Cross-Feeding Interactions between Bifidobacterium longum subsp. longum NCC2705 and Eubacterium rectale ATCC 33656 Explain the Bifidogenic and Butyrogenic Effects of Arabinoxylan Oligosaccharides

(2015) Audrey Rivière et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Faecalibacterium prausnitzii prevents physiological damages in a chronic low-grade inflammation murine model

(2015) Rebeca Martín et al.   BMC MICROBIOLOGY

Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function

(2015) Caleb J. Kelly et al.   Cell Host & Microbe

The gut microbiome in autoimmunity: Sex matters

(2015) Andres Gomez et al.   CLINICAL IMMUNOLOGY

Novel opportunities for next-generation probiotics targeting metabolic syndrome

(2015) Patrice D Cani et al.   CURRENT OPINION IN BIOTECHNOLOGY

Regulatory categories of probiotics across the globe: A review representing existing and recommended categorization

(2015) A Baldi et al.   Indian Journal of Medical Microbiology

Human autoimmune diseases: a comprehensive update

(2015) Lifeng Wang et al.   JOURNAL OF INTERNAL MEDICINE

The infant microbiome development: mom matters

(2015) Noel T. Mueller et al.   TRENDS IN MOLECULAR MEDICINE

Fecal microbiota transplantation broadening its application beyond intestinal disorders

(2015) Meng-Que Xu   WORLD JOURNAL OF GASTROENTEROLOGY

Vitamin-mediated immune regulation in the development of inflammatory diseases

(2015) Hidehiko Suzuki et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Dynamic changes in short- and long-term bacterial composition following fecal microbiota transplantation for recurrent Clostridium difficile infection

(2015) Alexa Weingarden et al.   Microbiome

Vitamin B 12 as a Modulator of Gut Microbial Ecology

(2014) Patrick H. Degnan et al.   Cell Metabolism

Arthritis susceptibility and the gut microbiome

(2014) Veena Taneja   FEBS LETTERS

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

(2014) Nagendra Singh et al.   IMMUNITY

Rheumatic Fever, Autoimmunity, and Molecular Mimicry: The Streptococcal Connection

(2014) Madeleine W. Cunningham   INTERNATIONAL REVIEWS OF IMMUNOLOGY

The Impact of High-Fat Diet on Metabolism and Immune Defense in Small Intestine Mucosa

(2014) Jacek R. Wiśniewski et al.   JOURNAL OF PROTEOME RESEARCH

Diet, microbiota and autoimmune diseases

(2014) SM Vieira et al.   LUPUS

Recombinant Lactococcus lactis can make the difference in antigen-specific immune tolerance induction, the Type 1 Diabetes case

(2014) Sofie Robert et al.   Microbial Cell Factories

A Transgenic Probiotic Secreting a Parasite Immunomodulator for Site-Directed Treatment of Gut Inflammation

(2014) Rose A Whelan et al.   MOLECULAR THERAPY

The gut microbiota, bacterial metabolites and colorectal cancer

(2014) Petra Louis et al.   NATURE REVIEWS MICROBIOLOGY

Oral Administration of Recombinant Lactococcus lactis Expressing HSP65 and Tandemly Repeated P277 Reduces the Incidence of Type I Diabetes in Non-Obese Diabetic Mice

(2014) Yanjun Ma et al.   PLoS One

Breach of Tolerance: Primary Biliary Cirrhosis

(2014) Lifeng Wang et al.   SEMINARS IN LIVER DISEASE

Phylogeny, culturing, and metagenomics of the human gut microbiota

(2014) Alan W. Walker et al.   TRENDS IN MICROBIOLOGY

Intestinal microbiota in health and disease: Role of bifidobacteria in gut homeostasis

(2014) Rafael Tojo   WORLD JOURNAL OF GASTROENTEROLOGY

Understanding How Commensal Obligate Anaerobic Bacteria Regulate Immune Functions in the Large Intestine

(2014) Eva Maier et al.   Nutrients

Bifidobacteria: their impact on gut microbiota composition and their applications as probiotics in infants

(2013) Diana Di Gioia et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Bacteroides thetaiotaomicron and Faecalibacterium prausnitzii influence the production of mucus glycans and the development of goblet cells in the colonic epithelium of a gnotobiotic model rodent

(2013) Laura Wrzosek et al.   BMC BIOLOGY

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

(2013) Elaine Y. Hsiao et al.   CELL

Amelioration of experimental autoimmune encephalomyelitis by probiotic mixture is mediated by a shift in T helper cell immune response

(2013) Ho-Keun Kwon et al.   CLINICAL IMMUNOLOGY

Oral Delivery of IL-27 Recombinant Bacteria Attenuates Immune Colitis in Mice

(2013) Miranda L. Hanson et al.   GASTROENTEROLOGY

Progress towards butyrate-producing pharmabiotics:Butyricicoccus pullicaecorumcapsule and efficacy in TNBS models in comparison with therapeutics: Table 1

(2013) Venessa Eeckhaut et al.   GUT

Summer Meeting 2013: growth and physiology of bifidobacteria

(2013) L. De Vuyst et al.   JOURNAL OF APPLIED MICROBIOLOGY

Beneficial Metabolic Effects of a Probiotic via Butyrate-induced GLP-1 Hormone Secretion

(2013) Hariom Yadav et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Faecalibacterium prausnitzii upregulates regulatory T cells and anti-inflammatory cytokines in treating TNBS-induced colitis

(2013) Xinyun Qiu et al.   Journal of Crohns & Colitis

Gut Microbiota Composition Modifies Fecal Metabolic Profiles in Mice

(2013) Ying Zhao et al.   JOURNAL OF PROTEOME RESEARCH

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Microbiota Dynamics in Patients Treated with Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection

(2013) Yang Song et al.   PLoS One

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

(2013) V. K. Ridaura et al.   SCIENCE

Vitamin-Mediated Regulation of Intestinal Immunity

(2013) Jun Kunisawa et al.   Frontiers in Immunology

Microencapsulation of Probiotic Cells for Food Applications

(2012) Thomas Heidebach et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Butyricicoccus pullicaecorumin inflammatory bowel disease

(2012) Venessa Eeckhaut et al.   GUT

Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice

(2012) Tatiana Takiishi et al.   JOURNAL OF CLINICAL INVESTIGATION

Metchnikoff and the microbiome

(2012) Scott H Podolsky   LANCET

Loss of Sex and Age Driven Differences in the Gut Microbiome Characterize Arthritis-Susceptible *0401 Mice but Not Arthritis-Resistant *0402 Mice

(2012) Andres Gomez et al.   PLoS One

Effects of probiotics on gut microbiota: mechanisms of intestinal immunomodulation and neuromodulation

(2012) Peera Hemarajata et al.   Therapeutic Advances in Gastroenterology

The MHC, disease and selection

(2011) John Trowsdale   IMMUNOLOGY LETTERS

Production of bioactive substances by intestinal bacteria as a basis for explaining probiotic mechanisms: Bacteriocins and conjugated linoleic acid

(2011) Eileen F. O'Shea et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

The Lactic Acid Bacterium Pediococcus acidilactici Suppresses Autoimmune Encephalomyelitis by Inducing IL-10-Producing Regulatory T Cells

(2011) Kazushiro Takata et al.   PLoS One

The Toll-Like Receptor 2 Pathway Establishes Colonization by a Commensal of the Human Microbiota

(2011) J. L. Round et al.   SCIENCE

Modulation of Mucosal Immune Response, Tolerance, and Proliferation in Mice Colonized by the Mucin-Degrader Akkermansia muciniphila

(2011) Muriel Derrien et al.   Frontiers in Microbiology

Treatment of colitis with a commensal gut bacterium engineered to secrete human tgf-β1 under the control of dietary xylan

(2010) Zaed Z.R. Hamady et al.   INFLAMMATORY BOWEL DISEASES

Intragastric administration of a superoxide dismutase-producing recombinant Lactobacillus casei BL23 strain attenuates DSS colitis in mice

(2010) Laurie Watterlot et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Central Nervous System Demyelinating Disease Protection by the Human Commensal Bacteroides fragilis Depends on Polysaccharide A Expression

(2010) J. Ochoa-Reparaz et al.   JOURNAL OF IMMUNOLOGY

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

AG013, a mouth rinse formulation of Lactococcus lactis secreting human Trefoil Factor 1, provides a safe and efficacious therapeutic tool for treating oral mucositis

(2010) Silvia Caluwaerts et al.   ORAL ONCOLOGY

Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation

(2010) L. Dethlefsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

(2010) C. De Filippo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Establishment of the gut microbiota in Western infants

(2009) I Adlerberth et al.   ACTA PAEDIATRICA

Xylan-regulated delivery of human keratinocyte growth factor-2 to the inflamed colon by the human anaerobic commensal bacterium Bacteroides ovatus

(2009) Z. Z R Hamady et al.   GUT

Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites

(2009) Steven A. Saenz et al.   IMMUNOLOGICAL REVIEWS

Microbial factories for recombinant pharmaceuticals

(2009) Neus Ferrer-Miralles et al.   Microbial Cell Factories

Orally administered L. lactis secreting an anti-TNF Nanobody demonstrate efficacy in chronic colitis

(2009) K Vandenbroucke et al.   Mucosal Immunology

Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla

(2009) M. A. Mahowald et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human-derived probiotic Lactobacillus reuteri demonstrate antimicrobial activities targeting diverse enteric bacterial pathogens

(2008) Jennifer K. Spinler et al.   ANAEROBE

Lactobacillus casei suppresses experimental arthritis by down-regulating T helper 1 effector functions

(2008) Jae-Seon So et al.   MOLECULAR IMMUNOLOGY

Lactobacillus casei potentiates induction of oral tolerance in experimental arthritis

(2008) Jae-Seon So et al.   MOLECULAR IMMUNOLOGY

A microbial symbiosis factor prevents intestinal inflammatory disease

(2008) Sarkis K. Mazmanian et al.   NATURE

Strain-dependent effects of probiotic lactobacilli on EAE autoimmunity

(2008) Catharina B.M. Maassen et al.   VACCINE