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Title
Cardiac cAMP: production, hydrolysis, modulation and detection
Authors
Keywords
-
Journal
Frontiers in Pharmacology
Volume 6, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2015-10-01
DOI
10.3389/fphar.2015.00203
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Note: Only part of the references are listed.- A systemicPasteurella multocidatoxin aggravates cardiac hypertrophy and fibrosis in mice
- (2015) Markus Weise et al. CELLULAR MICROBIOLOGY
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- (2015) Morgane Bellot et al. Nature Chemical Biology
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- (2014) Leanna Cheung et al. BIOCHEMICAL PHARMACOLOGY
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- (2014) Roland Seifert BIOCHEMICAL PHARMACOLOGY
- Discovery of triazines as selective PDE4B versus PDE4D inhibitors
- (2014) Timothy J. Hagen et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- CANDLES, an assay for monitoring GPCR induced cAMP generation in cell cultures
- (2014) Ashutosh Trehan et al. Cell Communication and Signaling
- A Cell-Permeable Inhibitor to Trap Gαq Proteins in the Empty Pocket Conformation
- (2014) Anna-Lena Schmitz et al. CHEMISTRY & BIOLOGY
- HCN channels: new roles in sinoatrial node function
- (2014) Christian Wahl-Schott et al. CURRENT OPINION IN PHARMACOLOGY
- Phosphodiesterase 3A1 Protects the Heart Against Angiotensin II–induced Cardiac Remodeling Through Regulation of Transforming Growth Factor-β Expression
- (2014) Shoji Iwaya et al. International Heart Journal
- Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis
- (2014) Nikoleta G Tsvetanova et al. Nature Chemical Biology
- Non-classical regulation of β1- and β2-adrenoceptor-mediated inotropic responses in rat heart ventricle by the G protein Gi
- (2014) Caroline Bull Melsom et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Cyclic AMP synthesis and hydrolysis in the normal and failing heart
- (2014) Aziz Guellich et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Adrenergic signaling in heart failure: a balance of toxic and protective effects
- (2014) Anthony J. Baker PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Engineering of a red-light-activated human cAMP/cGMP-specific phosphodiesterase
- (2014) C. Gasser et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- cAMP signaling microdomains and their observation by optical methods
- (2014) Davide Calebiro et al. Frontiers in Cellular Neuroscience
- Optogenetic sensors and effectors: CHROMus—the Cornell Heart Lung Blood Institute Resource for Optogenetic Mouse Signaling
- (2014) Bo Shui et al. Frontiers in Physiology
- Compartmentation of cAMP signalling in cardiomyocytes in health and disease
- (2013) R. K. Perera et al. Acta Physiologica
- The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1)
- (2013) Delphine Courilleau et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- PDE3, but not PDE4, reduces β1- and β2-adrenoceptor-mediated inotropic and lusitropic effects in failing ventricle from metoprolol-treated patients
- (2013) Peter Molenaar et al. BRITISH JOURNAL OF PHARMACOLOGY
- L-type calcium channel targeting and local signalling in cardiac myocytes
- (2013) Robin M. Shaw et al. CARDIOVASCULAR RESEARCH
- Type 5 Adenylyl Cyclase Increases Oxidative Stress by Transcriptional Regulation of Manganese Superoxide Dismutase via the SIRT1/FoxO3a Pathway
- (2013) Lo Lai et al. CIRCULATION
- Biophysical Techniques for Detection of cAMP and cGMP in Living Cells
- (2013) Julia Sprenger et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Architectural and functional roles of A kinase–anchoring proteins in cAMP microdomains
- (2013) Michael S. Kapiloff et al. JOURNAL OF GENERAL PHYSIOLOGY
- Direct Light-up of cAMP Derivatives in Living Cells by Click Reactions
- (2013) Kenichiro Ito et al. MOLECULES
- New perspectives in cyclic nucleotide-mediated functions in the CNS: the emerging role of cyclic nucleotide-gated (CNG) channels
- (2013) Maria Vittoria Podda et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Probing Heterotrimeric G Protein Activation: Applications to Biased Ligands
- (2012) Colette Denis et al. CURRENT PHARMACEUTICAL DESIGN
- MRP4 and CFTR in the regulation of cAMP and β-adrenergic contraction in cardiac myocytes
- (2012) Zachary M. Sellers et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Identification of a Tetrahydroquinoline Analog as a Pharmacological Inhibitor of the cAMP-binding Protein Epac
- (2012) Delphine Courilleau et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Separate roles of PKA and EPAC in renal function unraveled by the optogenetic control of cAMP levels in vivo
- (2012) M. Efetova et al. JOURNAL OF CELL SCIENCE
- Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice
- (2012) Alexander Froese et al. JOURNAL OF CLINICAL INVESTIGATION
- HCN Channels and Heart Rate
- (2012) Pietro Scicchitano et al. MOLECULES
- A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer
- (2012) Stefanie Blättermann et al. Nature Chemical Biology
- Isoform-specific antagonists of exchange proteins directly activated by cAMP
- (2012) T. Tsalkova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cyclic Nucleotide Compartmentalization: Contributions of Phosphodiesterases and ATP-Binding Cassette Transporters
- (2011) Satish Cheepala et al. Annual Review of Pharmacology and Toxicology
- Cyclic nucleotide phosphodiesterase 1A: a key regulator of cardiac fibroblast activation and extracellular matrix remodeling in the heart
- (2011) Clint L. Miller et al. BASIC RESEARCH IN CARDIOLOGY
- Impact of divalent metal ions on regulation of adenylyl cyclase isoforms by forskolin analogs
- (2011) Miriam Erdorf et al. BIOCHEMICAL PHARMACOLOGY
- Update on roflumilast, a phosphodiesterase 4 inhibitor for the treatment of chronic obstructive pulmonary disease
- (2011) Klaus F. Rabe BRITISH JOURNAL OF PHARMACOLOGY
- Novel blockers of hyperpolarization-activated current with isoform selectivity in recombinant cells and native tissue
- (2011) Martina Del Lungo et al. BRITISH JOURNAL OF PHARMACOLOGY
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- cAMP: Novel concepts in compartmentalised signalling
- (2011) Helen V. Edwards et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
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- Adenylyl Cyclase 6 Deletion Reduces Left Ventricular Hypertrophy, Dilation, Dysfunction, and Fibrosis in Pressure-Overloaded Female Mice
- (2010) Tong Tang et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
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- (2010) Amanda G. Vang et al. PLoS One
- The preclinical pharmacology of roflumilast – A selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease
- (2010) Armin Hatzelmann et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
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- (2010) V. O. Nikolaev et al. SCIENCE
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- (2010) M. L. Halls et al. Cold Spring Harbor Perspectives in Biology
- Structural Basis for Inhibition of Mammalian Adenylyl Cyclase by Calcium†
- (2009) Tung-Chung Mou et al. BIOCHEMISTRY
- Integrated modulation of phorbol ester-induced Raf activation in EL4 lymphoma cells
- (2009) Shujie Han et al. CELLULAR SIGNALLING
- Multivalent-Based Drug Design Applied to Serotonin 5-HT4 Receptor Oligomers
- (2009) Frank Lezoualc'h et al. CURRENT PHARMACEUTICAL DESIGN
- Compartmentalized signalling: spatial regulation of cAMP by the action of compartmentalized phosphodiesterases
- (2009) George S. Baillie FEBS Journal
- ASB16165, a novel inhibitor for phosphodiesterase 7A (PDE7A), suppresses IL-12-induced IFN-γ production by mouse activated T lymphocytes
- (2009) Kumiko Kadoshima-Yamaoka et al. IMMUNOLOGY LETTERS
- An Adenylyl Cyclase-mAKAPβ Signaling Complex Regulates cAMP Levels in Cardiac Myocytes
- (2009) Michael S. Kapiloff et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Soluble Adenylyl Cyclase Controls Mitochondria-dependent Apoptosis in Coronary Endothelial Cells
- (2009) Sanjeev Kumar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Critical role of the N-terminal cyclic AMP-binding domain of Epac2 in its subcellular localization and function
- (2009) Manabu Niimura et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Identification of Potential Pharmacological Targets by Analysis of the Comprehensive G Protein-Coupled Receptor Repertoire in the Four Cardiac Chambers
- (2009) T. Moore-Morris et al. MOLECULAR PHARMACOLOGY
- Temporally precise in vivo control of intracellular signalling
- (2009) Raag D. Airan et al. NATURE
- Novel Genetically Encoded Biosensors Using Firefly Luciferase
- (2008) Frank Fan et al. ACS Chemical Biology
- Epac and PKA: a tale of two intracellular cAMP receptors
- (2008) Xiaodong Cheng et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Vasoconstrictive effect of hydrogen sulfide involves downregulation of cAMP in vascular smooth muscle cells
- (2008) Jia Jia Lim et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Anatomical Profiling of G Protein-Coupled Receptor Expression
- (2008) Jean B. Regard et al. CELL
- Epac Mediates β-Adrenergic Receptor–Induced Cardiomyocyte Hypertrophy
- (2008) Mélanie Métrich et al. CIRCULATION RESEARCH
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- (2008) Mei Hua Gao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Critical Role of PDE4D in β2-Adrenoceptor-dependent cAMP Signaling in Mouse Embryonic Fibroblasts
- (2008) Matthew D. Bruss et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of Gαiand Subsequent Uncoupling of Receptor-GαiSignaling byPasteurella multocidaToxin
- (2008) Joachim H. C. Orth et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Multidrug resistance-associated protein 4 regulates cAMP-dependent signaling pathways and controls human and rat SMC proliferation
- (2008) Yassine Sassi et al. JOURNAL OF CLINICAL INVESTIGATION
- Negative regulation of β-adrenergic function by hydrogen sulphide in the rat hearts
- (2008) Qian Chen Yong et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Cyclic nucleotide analogs as probes of signaling pathways
- (2008) Heiko Poppe et al. NATURE METHODS
- The A-kinase anchoring protein Yotiao binds and regulates adenylyl cyclase in brain
- (2008) L. A. Piggott et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pharmacological PKA Inhibition: All May Not Be What It Seems
- (2008) A. J. Murray Science Signaling
- Calcium Cycling and Signaling in Cardiac Myocytes
- (2007) Donald M. Bers Annual Review of Physiology
- Adenylyl Cyclase Type 6 Deletion Decreases Left Ventricular Function via Impaired Calcium Handling
- (2007) Tong Tang et al. CIRCULATION
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