Phosphodiesterase 4B in the cardiac L-type Ca2+ channel complex regulates Ca2+ current and protects against ventricular arrhythmias in mice

Conserved expression and functions of PDE4 in rodent and human heart

(2010) Wito Richter et al.   BASIC RESEARCH IN CARDIOLOGY

Sympathetic Stimulation of Adult Cardiomyocytes Requires Association of AKAP5 With a Subpopulation of L-Type Calcium Channels

(2010) C. Blake Nichols et al.   CIRCULATION RESEARCH

Phosphodiesterase 8A (PDE8A) regulates excitation–contraction coupling in ventricular myocytes

(2010) Enrico Patrucco et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

CaV1.2  -subunit coordinates CaMKII-triggered cardiomyocyte death and afterdepolarizations

(2010) O. M. Koval et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Mechanism of Calcium Channel Regulation in the Fight-or-Flight Response

(2010) M. D. Fuller et al.   Science Signaling

Decreased Expression and Activity of cAMP Phosphodiesterases in Cardiac Hypertrophy and Its Impact on β-Adrenergic cAMP Signals

(2009) Aniella Abi-Gerges et al.   CIRCULATION RESEARCH

Differential Association of Phosphodiesterase 4D Isoforms with β2-Adrenoceptor in Cardiac Myocytes

(2009) Vania De Arcangelis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Cardiac IKsPotassium Channel Macromolecular Complex Includes the Phosphodiesterase PDE4D3

(2009) Cecile Terrenoire et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conditional FKBP12.6 Overexpression in Mouse Cardiac Myocytes Prevents Triggered Ventricular Tachycardia Through Specific Alterations in Excitation- Contraction Coupling

(2008) Barnabas Gellen et al.   CIRCULATION

Spatiotemporal Dynamics of β-Adrenergic cAMP Signals and L-Type Ca 2+ Channel Regulation in Adult Rat Ventricular Myocytes

(2008) Jérôme Leroy et al.   CIRCULATION RESEARCH

Signaling from β1- and β2-adrenergic receptors is defined by differential interactions with PDE4

(2008) Wito Richter et al.   EMBO JOURNAL

What role does modulation of the ryanodine receptor play in cardiac inotropy and arrhythmogenesis?

(2008) D.A. Eisner et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY