Impact of New-Generation Lipid Emulsions on Cellular Mechanisms of Parenteral Nutrition–Associated Liver Disease

Efficacy and Safety of the Farnesoid X Receptor Agonist Obeticholic Acid in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease

(2013) Sunder Mudaliar et al.   GASTROENTEROLOGY

Phytosterols Promote Liver Injury and Kupffer Cell Activation in Parenteral Nutrition-Associated Liver Disease

(2013) K. C. El Kasmi et al.   Science Translational Medicine

The Role of Endoplasmic Reticulum in Hepatic Lipid Homeostasis and Stress Signaling

(2012) Suneng Fu et al.   Cell Metabolism

Vitamin E and nonalcoholic fatty liver disease

(2012) Tommy Pacana et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Role of Obesity and Lipotoxicity in the Development of Nonalcoholic Steatohepatitis: Pathophysiology and Clinical Implications

(2012) Kenneth Cusi   GASTROENTEROLOGY

Endocrine fibroblast growth factors 15/19 and 21: from feast to famine

(2012) M. J. Potthoff et al.   GENES & DEVELOPMENT

Enteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs

(2011) Ajay Kumar Jain et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Selective Activation of Nuclear Bile Acid Receptor FXR in the Intestine Protects Mice Against Cholestasis

(2011) Salvatore Modica et al.   GASTROENTEROLOGY

Toll-like receptor 4-dependent Kupffer cell activation and liver injury in a novel mouse model of parenteral nutrition and intestinal injury

(2011) Karim C. El Kasmi et al.   HEPATOLOGY

Effect of Vitamin E or Metformin for Treatment of Nonalcoholic Fatty Liver Disease in Children and Adolescents

(2011) Joel E. Lavine   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Role of Parenteral Lipids in the Development of Advanced Intestinal Failure–Associated Liver Disease in Infants

(2011) Ivan R. Diamond et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Parenteral Plant Sterols and Intestinal Failure–associated Liver Disease in Neonates

(2011) Annika Kurvinen et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Decreased Postnatal Docosahexaenoic and Arachidonic Acid Blood Levels in Premature Infants are Associated with Neonatal Morbidities

(2011) Camilia R. Martin et al.   JOURNAL OF PEDIATRICS

Intravenous Fat Emulsions Reduction for Patients with Parenteral Nutrition–Associated Liver Disease

(2011) Mary Petrea Cober et al.   JOURNAL OF PEDIATRICS

FGF19 as a Postprandial, Insulin-Independent Activator of Hepatic Protein and Glycogen Synthesis

(2011) S. Kir et al.   SCIENCE

Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR

(2010) Antonia H. Tolson et al.   ADVANCED DRUG DELIVERY REVIEWS

Review article: epidemiology, pathogenesis and potential treatments of paediatric non-alcoholic fatty liver disease

(2010) N. J. BARSHOP et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Getting the mOST from OST: Role of organic solute transporter, OSTα-OSTβ, in bile acid and steroid metabolism

(2010) Paul A. Dawson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Mechanisms and clinical implications of hepatocyte lipoapoptosis

(2010) Sophie C Cazanave et al.   Clinical Lipidology

Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites

(2010) Brent A. Neuschwander-Tetri   HEPATOLOGY

Chronic Parenteral Nutrition Induces Hepatic Inflammation, Steatosis, and Insulin Resistance in Neonatal Pigs

(2010) Barbara Stoll et al.   JOURNAL OF NUTRITION

Novel Neonatal Piglet Models of Surgical Short Bowel Syndrome With Intestinal Failure

(2010) Justine M Turner et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis

(2010) Arun J. Sanyal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neonatal Outcomes of Extremely Preterm Infants From the NICHD Neonatal Research Network

(2010) B. J. Stoll et al.   PEDIATRICS

The Role of Inflammation in Cholestasis: Clinical and Basic Aspects

(2010) Astrid Kosters et al.   SEMINARS IN LIVER DISEASE

Nuclear receptors: mediators and modifiers of inflammation-induced cholestasis

(2009) Jaap Mulder   Frontiers in Bioscience-Landmark

Nuclear receptor ligands in therapy of cholestatic liver disease

(2009) Ekkehard Sturm   Frontiers in Bioscience-Landmark

Vitamin E Requirements in Parenteral Nutrition

(2009) Hans K. Biesalski   GASTROENTEROLOGY

Fatty Acids Modulate Toll-like Receptor 4 Activation through Regulation of Receptor Dimerization and Recruitment into Lipid Rafts in a Reactive Oxygen Species-dependent Manner

(2009) Scott W. Wong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New molecular insights into the mechanisms of cholestasis

(2009) Martin Wagner et al.   JOURNAL OF HEPATOLOGY

Towards Establishing Dietary Reference Intakes for Eicosapentaenoic and Docosahexaenoic Acids

(2009) William S. Harris et al.   JOURNAL OF NUTRITION

Changing the Paradigm: Omegaven for the Treatment of Liver Failure in Pediatric Short Bowel Syndrome

(2009) Ivan R Diamond et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Lipotoxicity in nonalcoholic fatty liver disease: not all lipids are created equal

(2009) Naim Alkhouri et al.   Expert Review of Gastroenterology & Hepatology

Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases

(2008) James P. Hardwick   BIOCHEMICAL PHARMACOLOGY

Pharmaceutical and clinical aspects of parenteral lipid emulsions in neonatology

(2008) David F. Driscoll et al.   CLINICAL NUTRITION

N-3 polyunsaturated fatty acid regulation of hepatic gene transcription

(2008) Donald B Jump   CURRENT OPINION IN LIPIDOLOGY

Farnesoid X receptor antagonizes nuclear factor κB in hepatic inflammatory response

(2008) Yan-Dong Wang et al.   HEPATOLOGY

Targeting bile-acid signalling for metabolic diseases

(2008) Charles Thomas et al.   NATURE REVIEWS DRUG DISCOVERY

Phytosterolemia in parenteral nutrition patients: Implications for liver disease development

(2008) Josep M. Llop et al.   NUTRITION

Parenteral fish oil as monotherapy for patients with parenteral nutrition-associated liver disease

(2008) Vincent E. de Meijer et al.   PEDIATRIC SURGERY INTERNATIONAL

Safety and Efficacy of a Fish-Oil-Based Fat Emulsion in the Treatment of Parenteral Nutrition-Associated Liver Disease

(2008) K. M. Gura et al.   PEDIATRICS

Endocrine FGFs and Klothos: emerging concepts

(2008) Makoto Kuro-o   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Regulation of Transporters by Nuclear Hormone Receptors: Implications during Inflammation

(2007) Shirley Teng et al.   MOLECULAR PHARMACEUTICS