Mechanisms and clinical implications of hepatocyte lipoapoptosis

Diabetes and apoptosis: lipotoxicity

(2009) Christine M. Kusminski et al.   APOPTOSIS

Life and death by death receptors

(2009) Maria Eugenia Guicciardi et al.   FASEB JOURNAL

Antiapoptotic Effect of c-Jun N-terminal Kinase-1 through Mcl-1 Stabilization in TNF-Induced Hepatocyte Apoptosis

(2009) Yuzo Kodama et al.   GASTROENTEROLOGY

Differential expression of lumican and fatty acid binding protein-1: New insights into the histologic spectrum of nonalcoholic fatty liver disease

(2009) Michael Charlton et al.   HEPATOLOGY

Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis

(2009) Rafal P. Witek et al.   HEPATOLOGY

Cytokeratin-18 fragment levels as noninvasive biomarkers for nonalcoholic steatohepatitis: A multicenter validation study

(2009) Ariel E. Feldstein et al.   HEPATOLOGY

Mcl-1 Degradation during Hepatocyte Lipoapoptosis

(2009) Howard C. Masuoka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

JNK1-dependent PUMA Expression Contributes to Hepatocyte Lipoapoptosis

(2009) Sophie C. Cazanave et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatic Lipid Partitioning and Liver Damage in Nonalcoholic Fatty Liver Disease

(2009) Zheng Zheng Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members

(2009) Tristan Gallenne et al.   JOURNAL OF CELL BIOLOGY

Diet-induced alterations in intestinal and extrahepatic lipid metabolism in liver fatty acid binding protein knockout mice

(2009) Elizabeth P. Newberry et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cells

(2009) Yuren Wei et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Liver NF-κB and AP-1 DNA Binding in Obese Patients

(2009) Luis A. Videla et al.   Obesity

Gene expression in human NAFLD

(2008) Dario Greco et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

An update on lipotoxic endoplasmic reticulum stress in pancreatic β-cells

(2008) Miriam Cnop et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim

(2008) A M Jabbour et al.   CELL DEATH AND DIFFERENTIATION

Hepatic Stearoyl-CoA Desaturase (SCD)-1 Activity and Diacylglycerol but Not Ceramide Concentrations Are Increased in the Nonalcoholic Human Fatty Liver

(2008) A. Kotronen et al.   DIABETES

The lysosomal-mitochondrial axis in free fatty acid-induced hepatic lipotoxicity

(2008) ZhengZheng Li et al.   HEPATOLOGY

Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance

(2008) Rajat Singh et al.   HEPATOLOGY

Analysis of hepatic genes involved in the metabolism of fatty acids and iron in nonalcoholic fatty liver disease

(2008) Hironori Mitsuyoshi et al.   HEPATOLOGY RESEARCH

Silencing of Hepatic Fatty Acid Transporter Protein 5in VivoReverses Diet-induced Non-alcoholic Fatty Liver Disease and Improves Hyperglycemia

(2008) Holger Doege et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protection from High Fat Diet-induced Increase in Ceramide in Mice Lacking Plasminogen Activator Inhibitor 1

(2008) Charmi Shah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Initiation and execution of lipotoxic ER stress in pancreatic  -cells

(2008) D. A. Cunha et al.   JOURNAL OF CELL SCIENCE

Hepatic free fatty acids accumulate in experimental steatohepatitis: Role of adaptive pathways

(2008) Claire Z. Larter et al.   JOURNAL OF HEPATOLOGY

MCD-induced steatohepatitis is associated with hepatic adiponectin resistance and adipogenic transformation of hepatocytes

(2008) Claire Z. Larter et al.   JOURNAL OF HEPATOLOGY

Trans-11 Vaccenic Acid Dietary Supplementation Induces Hypolipidemic Effects in JCR:LA-cp Rats

(2008) Ye Wang et al.   JOURNAL OF NUTRITION

Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins

(2008) J. E. Chipuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A new model for nonalcoholic steatohepatitis in the rat utilizing total enteral nutrition to overfeed a high-polyunsaturated fat diet

(2007) January N. Baumgardner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Effects of n-3 polyunsaturated fatty acids in subjects with nonalcoholic fatty liver disease

(2007) L. Spadaro et al.   DIGESTIVE AND LIVER DISEASE

Hepatic Fatty Acid Transporter Cd36 Is a Common Target of LXR, PXR, and PPARγ in Promoting Steatosis

(2007) Jie Zhou et al.   GASTROENTEROLOGY

Activation and Dysregulation of the Unfolded Protein Response in Nonalcoholic Fatty Liver Disease

(2007) Puneet Puri et al.   GASTROENTEROLOGY

Nutritional assessment and hepatic fatty acid composition in non-alcoholic fatty liver disease (NAFLD): A cross-sectional study

(2007) Johane P. Allard et al.   JOURNAL OF HEPATOLOGY

Apoptosis: controlled demolition at the cellular level

(2007) Rebecca C. Taylor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY