Mineral particles stimulate innate immunity through neutrophil extracellular traps containing HMGB1

A story told by a single nanoparticle in the body fluid: demonstration of dissolution-reprecipitation of nanocrystals in a biological system

(2015) Cheng-Yeu Wu et al.   Nanomedicine

Nanoparticle conversion to biofilms: in vitro demonstration using serum-derived mineralo-organic nanoparticles

(2015) Tsui-Yin Wong et al.   Nanomedicine

Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis

(2015) A. Warnatsch et al.   SCIENCE

Histone Deimination As a Response to Inflammatory Stimuli in Neutrophils

(2014) I. Neeli et al.   JOURNAL OF IMMUNOLOGY

Of nanobacteria, nanoparticles, biofilms and their role in health and disease: facts, fancy and future

(2014) Jan Martel et al.   Nanomedicine

Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens

(2014) Nora Branzk et al.   NATURE IMMUNOLOGY

Membrane Vesicles Nucleate Mineralo-organic Nanoparticles and Induce Carbonate Apatite Precipitation in Human Body Fluids

(2013) Cheng-Yeu Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tuning Innate Immune Activation by Surface Texturing of Polymer Microparticles: The Role of Shape in Inflammasome Activation

(2013) C. A. Vaine et al.   JOURNAL OF IMMUNOLOGY

Pyocyanin-Enhanced Neutrophil Extracellular Trap Formation Requires the NADPH Oxidase

(2013) Balázs Rada et al.   PLoS One

Bions: A Family of Biomimetic Mineralo-Organic Complexes Derived from Biological Fluids

(2013) Cheng-Yeu Wu et al.   PLoS One

Biomimetic Properties of Minerals and the Search for Life in the Martian Meteorite ALH84001

(2012) Jan Martel et al.   Annual Review of Earth and Planetary Sciences

Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity

(2012) S. Sangaletti et al.   BLOOD

Clearance of Fetuin-A–Containing Calciprotein Particles Is Mediated by Scavenger Receptor-A

(2012) Marietta Herrmann et al.   CIRCULATION RESEARCH

Neutrophil extracellular traps: Is immunity the second function of chromatin?

(2012) Volker Brinkmann et al.   JOURNAL OF CELL BIOLOGY

Neutrophil Extracellular Traps: Double-Edged Swords of Innate Immunity

(2012) M. J. Kaplan et al.   JOURNAL OF IMMUNOLOGY

Requirements for NADPH oxidase and myeloperoxidase in neutrophil extracellular trap formation differ depending on the stimulus

(2012) Heather Parker et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Unknown

(2012) Huan Yang et al.   MOLECULAR MEDICINE

Physicochemical and Biological Properties of Biomimetic Mineralo-Protein Nanoparticles Formed Spontaneously in Biological Fluids

(2012) Hsin-Hsin Peng et al.   Small

Comprehensive proteomic analysis of mineral nanoparticles derived from human body fluids and analyzed by liquid chromatography–tandem mass spectrometry

(2011) Jan Martel et al.   ANALYTICAL BIOCHEMISTRY

HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection

(2011) Ulf Andersson et al.   Annual Review of Immunology

Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality

(2011) Q Remijsen et al.   CELL DEATH AND DIFFERENTIATION

Fetuin-A Regulation of Calcified Matrix Metabolism

(2011) Willi Jahnen-Dechent et al.   CIRCULATION RESEARCH

Neutrophil extracellular traps contain mitochondrial as well as nuclear DNA and exhibit inflammatory potential

(2011) Ravi S. Keshari et al.   CYTOMETRY PART A

Serum-derived nanoparticles:de novogeneration and growthin vitro, and internalization by mammalian cells in culture

(2011) Hsin-Hsin Peng et al.   Nanomedicine

Neutrophil Extracellular Trap Formation Is Associated with IL-1β and Autophagy-Related Signaling in Gout

(2011) Ioannis Mitroulis et al.   PLoS One

HMGB1 and RAGE in Inflammation and Cancer

(2010) Gary P. Sims et al.   Annual Review of Immunology

Neutrophils: Cinderella of innate immune system

(2010) V. Kumar et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

A Novel Mechanism of Rapid Nuclear Neutrophil Extracellular Trap Formation in Response to Staphylococcus aureus

(2010) F. H. Pilsczek et al.   JOURNAL OF IMMUNOLOGY

Macrophage phagocytosis of neutrophils at inflammatory/infectious foci: a cooperative mechanism in the control of infection and infectious inflammation

(2010) M. T. Silva   JOURNAL OF LEUKOCYTE BIOLOGY

Ultrastructural Analysis of Vascular Calcifications in Uremia

(2010) G. Schlieper et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Fetuin-Mineral Complex Reflects Extraosseous Calcification Stress in CKD

(2010) T. Hamano et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Critical Evaluation of Gamma-Irradiated Serum Used as Feeder in the Culture and Demonstration of Putative Nanobacteria and Calcifying Nanoparticles

(2010) Jan Martel et al.   PLoS One

Hydroxyapatite nano and microparticles: Correlation of particle properties with cytotoxicity and biostability

(2009) M. Motskin et al.   BIOMATERIALS

Phagocytosis Independent Extracellular Nanoparticle Clearance by Human Immune Cells

(2009) Matthias Bartneck et al.   NANO LETTERS

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE

Putative Nanobacteria Represent Physiological Remnants and Culture By-Products of Normal Calcium Homeostasis

(2009) John D. Young et al.   PLoS One

Characterization of Granulations of Calcium and Apatite in Serum as Pleomorphic Mineralo-Protein Complexes and as Precursors of Putative Nanobacteria

(2009) John D. Young et al.   PLoS One

Fetuin-A/Albumin-Mineral Complexes Resembling Serum Calcium Granules and Putative Nanobacteria: Demonstration of a Dual Inhibition-Seeding Concept

(2009) Cheng-Yeu Wu et al.   PLoS One

The Rise and Fall of Nanobacteria

(2009) John D. Young et al.   SCIENTIFIC AMERICAN

ROLE OF TOLL-LIKE RECEPTORS 2 AND 4, AND THE RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS IN HIGH-MOBILITY GROUP BOX 1-INDUCED INFLAMMATION IN VIVO

(2009) Marieke A.D. van Zoelen et al.   SHOCK

A calculated response: control of inflammation by the innate immune system

(2008) Gregory M. Barton   JOURNAL OF CLINICAL INVESTIGATION

Purported nanobacteria in human blood as calcium carbonate nanoparticles

(2008) J. Martel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ETosis: A Novel Cell Death Pathway

(2008) F. Wartha et al.   Science Signaling

Effect of particle size on hydroxyapatite crystal-induced tumor necrosis factor alpha secretion by macrophages

(2007) Imad Nadra et al.   ATHEROSCLEROSIS