Hypoxia regulates RhoA and Wnt/β-catenin signaling in a context-dependent way to control re-differentiation of chondrocytes

Sulfated Hydrogel Matrices Direct Mitogenicity and Maintenance of Chondrocyte Phenotype through Activation of FGF Signaling

(2016) Ece Öztürk et al.   ADVANCED FUNCTIONAL MATERIALS

Hypoxia potentiates the BMP-2 driven COL2A1 stimulation in human articular chondrocytes via p38 MAPK

(2016) J.E. Lafont et al.   OSTEOARTHRITIS AND CARTILAGE

Interaction of HIF1α and β-catenin inhibits matrix metalloproteinase 13 expression and prevents cartilage damage in mice

(2016) Wafa Bouaziz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia-inducible factor 3-alpha expression is associated with the stable chondrocyte phenotype

(2015) Brandon D. Markway et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Hypoxic induction of T-type Ca2+channels in rat cardiac myocytes: role of HIF-1α and RhoA/ROCK signalling

(2015) P. González-Rodríguez et al.   JOURNAL OF PHYSIOLOGY-LONDON

Repair and tissue engineering techniques for articular cartilage

(2014) Eleftherios A. Makris et al.   Nature Reviews Rheumatology

Hypoxia Promotes the Production and Inhibits the Destruction of Human Articular Cartilage

(2013) Brendan L. Thoms et al.   ARTHRITIS AND RHEUMATISM

Probing the microenvironmental conditions for induction of superficial zone protein expression

(2013) R. Mhanna et al.   OSTEOARTHRITIS AND CARTILAGE

Correction: Association of pol Diversity with Antiretroviral Treatment Outcomes among HIV-Infected African Children

(2013) Iris Chen et al.   PLoS One

Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells

(2013) D. M. Gilkes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High targeted migration of human mesenchymal stem cells grown in hypoxia is associated with enhanced activation of RhoA

(2013) Grigory Vertelov et al.   Stem Cell Research & Therapy

Inhibition of RhoA but not ROCK induces chondrogenesis of chick limb mesenchymal cells

(2012) Min Jung Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hypoxia-driven pathways in bone development, regeneration and disease

(2012) Christa Maes et al.   Nature Reviews Rheumatology

Identification of signalling pathways triggered by changes in the mechanical environment in rat chondrocytes

(2012) P. Sanz-Ramos et al.   OSTEOARTHRITIS AND CARTILAGE

Combined 3D and hypoxic culture improves cartilage-specific gene expression in human chondrocytes

(2011) Casper B Foldager et al.   Acta Orthopaedica

Nkx3.2-induced suppression of Runx2 is a crucial mediator of hypoxia-dependent maintenance of chondrocyte phenotypes

(2011) Yoshitaka Kawato et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effects of oxygen and culture system on in vitro propagation and redifferentiation of osteoarthritic human articular chondrocytes

(2011) Karsten Schrobback et al.   CELL AND TISSUE RESEARCH

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

O2 regulates stem cells through Wnt/β-catenin signalling

(2010) Jolly Mazumdar et al.   NATURE CELL BIOLOGY

Hypoxia-inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction

(2010) Siyoung Yang et al.   NATURE MEDICINE

Hypoxia-inducible factor 1α inhibits the fibroblast-like markers type I and type III collagen during hypoxia-induced chondrocyte redifferentiation: Hypoxia not only induces type II collagen and aggrecan, but it also inhibits type I and type III collagen in the hypoxia-inducible factor 1α-dependent redifferentiation of chondrocytes

(2009) Elise Duval et al.   ARTHRITIS AND RHEUMATISM

Rho GTPase activity modulates Wnt3a/β-catenin signaling

(2009) Jessica Rossol-Allison et al.   CELLULAR SIGNALLING

The Transcriptional Activity of Sox9 in Chondrocytes Is Regulated by RhoA Signaling and Actin Polymerization

(2009) D. Kumar et al.   MOLECULAR AND CELLULAR BIOLOGY

Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

(2009) Baozhi Chen et al.   Nature Chemical Biology

Sustained hypoxia enhances chondrocyte matrix synthesis

(2008) Christian H. Coyle et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Hypoxic chondrogenic differentiation of human embryonic stem cells enhances cartilage protein synthesis and biomechanical functionality

(2008) E.J. Koay et al.   OSTEOARTHRITIS AND CARTILAGE