Hypoxia-inducible factor 3-alpha expression is associated with the stable chondrocyte phenotype

Hypoxia-Inducible Factor 3 Is an Oxygen-Dependent Transcription Activator and Regulates a Distinct Transcriptional Response to Hypoxia

(2014) Peng Zhang et al.   Cell Reports

Hypoxia Promotes the Production and Inhibits the Destruction of Human Articular Cartilage

(2013) Brendan L. Thoms et al.   ARTHRITIS AND RHEUMATISM

A novel splicing outcome reveals more than 2000 new mammalian protein isoforms

(2013) Laurence O. W. Wilson et al.   BIOINFORMATICS

Regulated Transcription of Human Matrix Metalloproteinase 13 (MMP13) and Interleukin-1β (IL1B) Genes in Chondrocytes Depends on Methylation of Specific Proximal Promoter CpG Sites

(2013) Ko Hashimoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differentially Expressed MicroRNAs in Chondrocytes from Distinct Regions of Developing Human Cartilage

(2013) Audrey McAlinden et al.   PLoS One

Hypoxia promotes redifferentiation and suppresses markers of hypertrophy and degeneration in both healthy and osteoarthritic chondrocytes

(2013) Brandon D Markway et al.   ARTHRITIS RESEARCH & THERAPY

Splice variants of the condensin II gene Ncaph2 include alternative reading frame translations of exon 1

(2012) Angelo Theodoratos et al.   FEBS Journal

A large-scale replication study for the association of rs17039192 in HIF-2α with knee osteoarthritis

(2012) Masahiro Nakajima et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Effects of oxygen and culture system on in vitro propagation and redifferentiation of osteoarthritic human articular chondrocytes

(2011) Karsten Schrobback et al.   CELL AND TISSUE RESEARCH

Roles of the human hypoxia-inducible factor (HIF)-3α variants in the hypoxia response

(2011) Minna Heikkilä et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

HIF-2α - a mediator of osteoarthritis?

(2010) Christopher L Murphy   CELL RESEARCH

Cell-specific and hypoxia-dependent regulation of human HIF-3α: inhibition of the expression of HIF target genes in vascular cells

(2010) Antje Augstein et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Hypoxia-inducible factor (HIF)-3α is subject to extensive alternative splicing in human tissues and cancer cells and is regulated by HIF-1 but not HIF-2

(2010) Annika Pasanen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

(2010) Taku Saito et al.   NATURE MEDICINE

Hypoxia-inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction

(2010) Siyoung Yang et al.   NATURE MEDICINE

Temporal Exposure to Chondrogenic Factors Modulates Human Mesenchymal Stem Cell Chondrogenesis in Hydrogels

(2010) Amanda N. Buxton et al.   TISSUE ENGINEERING PART A

Anabolic and catabolic responses of human articular chondrocytes to varying oxygen percentages

(2010) Simon Ströbel et al.   ARTHRITIS RESEARCH & THERAPY

Hypoxia-inducible factor 1α inhibits the fibroblast-like markers type I and type III collagen during hypoxia-induced chondrocyte redifferentiation: Hypoxia not only induces type II collagen and aggrecan, but it also inhibits type I and type III collagen in the hypoxia-inducible factor 1α-dependent redifferentiation of chondrocytes

(2009) Elise Duval et al.   ARTHRITIS AND RHEUMATISM

The humanHIF(hypoxia-inducible factor)-3α gene is a HIF-1 target gene and may modulate hypoxic gene induction

(2009) Tetsuhiro Tanaka et al.   BIOCHEMICAL JOURNAL

Is Continuous Treatment with Transforming Growth Factor-Beta Necessary to Induce Chondrogenic Differentiation in Mesenchymal Stem Cells?

(2008) Hye-Joung Kim et al.   CELLS TISSUES ORGANS