Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma

Bidirectional apical–basal traffic of the cation-independent mannose-6-phosphate receptor in brain endothelial cells

(2017) Piotr Siupka et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Antibody therapies in CNS diseases

(2017) Per-Ola Freskgård et al.   NEUROPHARMACOLOGY

Iron uptake and transport across physiological barriers

(2016) Kari A. Duck et al.   BIOMETALS

Pharmacokinetic considerations of nanodelivery to the brain: Using modeling and simulations to predict the outcome of liposomal formulations

(2016) Annika Lindqvist et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

In vitro models of the blood–brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use

(2016) Hans C Helms et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Revisiting nanoparticle technology for blood–brain barrier transport: Unfolding at the endothelial gate improves the fate of transferrin receptor-targeted liposomes

(2016) Kasper Bendix Johnsen et al.   JOURNAL OF CONTROLLED RELEASE

Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases

(2016) Cláudia Saraiva et al.   JOURNAL OF CONTROLLED RELEASE

Internalization of targeted quantum dots by brain capillary endothelial cells in vivo

(2015) Sarah Paris-Robidas et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Expression of Iron-Related Proteins at the Neurovascular Unit Supports Reduction and Reoxidation of Iron for Transport Through the Blood-Brain Barrier

(2015) Annette Burkhart et al.   MOLECULAR NEUROBIOLOGY

Trafficking of Gold Nanoparticles Coated with the 8D3 Anti-Transferrin Receptor Antibody at the Mouse Blood–Brain Barrier

(2015) Itsaso Cabezón et al.   MOLECULAR PHARMACEUTICS

Increased brain uptake of targeted nanoparticles by adding an acid-cleavable linkage between transferrin and the nanoparticle core

(2015) Andrew J. Clark et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Novel Model for Brain Iron Uptake: Introducing the Concept of Regulation

(2014) Ian A Simpson et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A Human Blood-Brain Barrier Transcytosis Assay Reveals Antibody Transcytosis Influenced by pH-Dependent Receptor Binding

(2014) Hadassah Sade et al.   PLoS One

Glioma targeting and blood–brain barrier penetration by dual-targeting doxorubincin liposomes

(2013) Jian-Qing Gao et al.   BIOMATERIALS

Cell penetrating peptide tethered bi-ligand liposomes for delivery to brain in vivo: Biodistribution and transfection

(2013) Gitanjali Sharma et al.   JOURNAL OF CONTROLLED RELEASE

Blood–brain barrier structure and function and the challenges for CNS drug delivery

(2013) N. Joan Abbott   JOURNAL OF INHERITED METABOLIC DISEASE

Brain Uptake of a Fluorescent Vector Targeting the Transferrin Receptor: A Novel Application of in Situ Brain Perfusion

(2013) Wael Alata et al.   MOLECULAR PHARMACEUTICS

Transcytosis and brain uptake of transferrin-containing nanoparticles by tuning avidity to transferrin receptor

(2013) D. T. Wiley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional roles of transferrin in the brain

(2011) Dominique F. Leitner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Autofluorescent cells in rat brain can be convincing impostors in green fluorescent reporter studies

(2011) Nadja Spitzer et al.   JOURNAL OF NEUROSCIENCE METHODS

Boosting Brain Uptake of a Therapeutic Antibody by Reducing Its Affinity for a Transcytosis Target

(2011) Y. J. Yu et al.   Science Translational Medicine

Uptake and permeability studies of BBB-targeting immunoliposomes using the hCMEC/D3 cell line

(2010) Eleni Markoutsa et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Comparison of five different targeting ligands to enhance accumulation of liposomes into the brain

(2010) Inge van Rooy et al.   JOURNAL OF CONTROLLED RELEASE

Macromolecular drug transport into the brain using targeted therapy

(2009) Jacek Lichota et al.   JOURNAL OF NEUROCHEMISTRY

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Restricted transport of anti-transferrin receptor antibody (OX26) through the blood-brain barrier in the rat

(2003) Torben Moos et al.   JOURNAL OF NEUROCHEMISTRY