Bidirectional apical–basal traffic of the cation-independent mannose-6-phosphate receptor in brain endothelial cells

Polarized trafficking of the sorting receptor SorLA in neurons and MDCK cells

(2016) Stine C. Klinger et al.   FEBS Journal

Discovery of Novel Blood-Brain Barrier Targets to Enhance Brain Uptake of Therapeutic Antibodies

(2016) Y. Joy Yu Zuchero et al.   NEURON

Targeting Receptor-Mediated Transport for Delivery of Biologics Across the Blood-Brain Barrier

(2015) Jason M. Lajoie et al.   Annual Review of Pharmacology and Toxicology

Trafficking of Gold Nanoparticles Coated with the 8D3 Anti-Transferrin Receptor Antibody at the Mouse Blood–Brain Barrier

(2015) Itsaso Cabezón et al.   MOLECULAR PHARMACEUTICS

Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance

(2015) Zhen Zhao et al.   NATURE NEUROSCIENCE

LRP-1-mediated intracellular antibody delivery to the Central Nervous System

(2015) Xiaohe Tian et al.   Scientific Reports

A Triple Culture Model of the Blood-Brain Barrier Using Porcine Brain Endothelial cells, Astrocytes and Pericytes

(2015) Louiza Bohn Thomsen et al.   PLoS One

Subcellular localisation of retromer in post-endocytic pathways of polarised Madin-Darby canine kidney cells

(2014) Maravillas Mellado et al.   BIOLOGY OF THE CELL

Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants

(2014) Nga Bien-Ly et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Comparison of Five Peptide Vectors for Improved Brain Delivery of the Lysosomal Enzyme Arylsulfatase A

(2014) A. Bockenhoff et al.   JOURNAL OF NEUROSCIENCE

Dendritic Cells Utilize the Evolutionarily Conserved WASH and Retromer Complexes to Promote MHCII Recycling and Helper T Cell Priming

(2014) Daniel B. Graham et al.   PLoS One

Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates

(2014) Y. J. Yu et al.   Science Translational Medicine

A detailed method for preparation of a functional and flexible blood–brain barrier model using porcine brain endothelial cells

(2013) Adjanie Patabendige et al.   BRAIN RESEARCH

Pharmacokinetics and Brain Uptake of an IgG-TNF Decoy Receptor Fusion Protein Following Intravenous, Intraperitoneal, and Subcutaneous Administration in Mice

(2013) Rachita K. Sumbria et al.   MOLECULAR PHARMACEUTICS

RAB7L1 Interacts with LRRK2 to Modify Intraneuronal Protein Sorting and Parkinson’s Disease Risk

(2013) David A. MacLeod et al.   NEURON

Characterization of Adult Rat Astrocyte Cultures

(2013) Débora Guerini Souza et al.   PLoS One

Addressing Safety Liabilities of TfR Bispecific Antibodies That Cross the Blood-Brain Barrier

(2013) J. A. Couch et al.   Science Translational Medicine

Establishment of a simplified in vitro porcine blood–brain barrier model with high transendothelial electrical resistance

(2012) Adjanie Patabendige et al.   BRAIN RESEARCH

Selective plasma pharmacokinetics and brain uptake in the mouse of enzyme fusion proteins derived from species-specific receptor-targeted antibodies

(2012) Qing-Hui Zhou et al.   JOURNAL OF DRUG TARGETING

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in thetrans-Golgi network

(2012) Regina Wai-Yan Choy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transport of Arylsulfatase A across the Blood-Brain Barrierin Vitro

(2011) Frank Matthes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mannose-6-phosphate pathway: A review on its role in lysosomal function and dysfunction

(2011) Maria Francisca Coutinho et al.   MOLECULAR GENETICS AND METABOLISM

Paracellular Tightness and Claudin-5 Expression is Increased in the BCEC/Astrocyte Blood–Brain Barrier Model by Increasing Media Buffer Capacity During Growth

(2010) Hans Christian Helms et al.   AAPS Journal

Implication of mouse Vps26b–Vps29–Vps35 retromer complex in sortilin trafficking

(2010) Ekyune Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evolution of Mannose 6-Phosphate Receptors (MPR300 and 46): Lysosomal Enzyme Sorting Proteins

(2010) S. Nadimpalli et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Retromer-mediated direct sorting is required for proper endosomal recycling of the mammalian iron transporter DMT1

(2010) M. Tabuchi et al.   JOURNAL OF CELL SCIENCE

New Strategies for Enzyme Replacement Therapy for Lysosomal Storage Diseases

(2010) Jeffrey H. Grubb et al.   REJUVENATION RESEARCH

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Sorting of lysosomal proteins

(2008) Thomas Braulke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Tracing the Retrograde Route in Protein Trafficking

(2008) Ludger Johannes et al.   CELL