Sex differences in protein expression in the mouse brain and their perturbations in a model of Down syndrome

Why Women Have More Alzheimer's Disease Than Men: Gender and Mitochondrial Toxicity of Amyloid-β Peptide

(2017) Jose Viña et al.   JOURNAL OF ALZHEIMERS DISEASE

Hippocampal learning, memory, and neurogenesis: Effects of sex and estrogens across the lifespan in adults

(2015) Paula Duarte-Guterman et al.   HORMONES AND BEHAVIOR

Learning and memory: Steroids and epigenetics

(2015) Alessandra Colciago et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Long-term effects of neonatal treatment with fluoxetine on cognitive performance in Ts65Dn mice

(2015) Fiorenza Stagni et al.   NEUROBIOLOGY OF DISEASE

Escape from X Inactivation Varies in Mouse Tissues

(2015) Joel B. Berletch et al.   PLoS Genetics

Protein Dynamics Associated with Failed and Rescued Learning in the Ts65Dn Mouse Model of Down Syndrome

(2015) Md. Mahiuddin Ahmed et al.   PLoS One

NMDA receptor-deficient mice display sexual dimorphism in the onset and severity of behavioural abnormalities

(2014) M. Milenkovic et al.   GENES BRAIN AND BEHAVIOR

Abnormal microglial activation in theCstb−/−mouse, a model for progressive myoclonus epilepsy, EPM1

(2014) Olesya Okuneva et al.   GLIA

Fluoxetine Signature on Hippocampal MAPK Signalling in Sex-Dependent Manner

(2014) Milos Mitic et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Reduction in traumatic brain injury-induced oxidative stress, apoptosis, and calcium entry in rat hippocampus by melatonin: Possible involvement of TRPM2 channels

(2014) Vehbi Yürüker et al.   METABOLIC BRAIN DISEASE

Preclinical research: Make mouse studies work

(2014) Steve Perrin   NATURE

Policy: NIH to balance sex in cell and animal studies

(2014) Janine A. Clayton et al.   NATURE

X chromosome regulation: diverse patterns in development, tissues and disease

(2014) Xinxian Deng et al.   NATURE REVIEWS GENETICS

The key role of transient receptor potential melastatin-2 channels in amyloid-β-induced neurovascular dysfunction

(2014) L. Park et al.   Nature Communications

Pharmacological approaches to improving cognitive function in Down syndrome: current status and considerations

(2014) Katheleen Gardiner   Drug Design Development and Therapy

Sex Differences in the Cholinergic Basal Forebrain in the Ts65Dn Mouse Model of Down Syndrome and Alzheimer's Disease

(2013) Christy M. Kelley et al.   BRAIN PATHOLOGY

Pharmacogenomics, pharmacokinetics and pharmacodynamics: interaction with biological differences between men and women

(2013) Flavia Franconi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Protein profiles in Tc1 mice implicate novel pathway perturbations in the Down syndrome brain

(2013) M. M. Ahmed et al.   HUMAN MOLECULAR GENETICS

Androgen and PARP-1 Regulation of TRPM2 Channels after Ischemic Injury

(2013) Takeru Shimizu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Genes That Escape X-Inactivation in Humans Have High Intraspecific Variability in Expression, Are Associated with Mental Impairment but Are Not Slow Evolving

(2013) Yuchao Zhang et al.   MOLECULAR BIOLOGY AND EVOLUTION

Fluoxetine in adulthood normalizes GABA release and rescues hippocampal synaptic plasticity and spatial memory in a mouse model of Down Syndrome

(2013) Tatjana Begenisic et al.   NEUROBIOLOGY OF DISEASE

The Cerebellum and Cognitive Function: 25 Years of Insight from Anatomy and Neuroimaging

(2013) Randy L. Buckner   NEURON

Gender-specific effects of fluoxetine on hippocampal glucocorticoid receptor phosphorylation and behavior in chronically stressed rats

(2013) Milos Mitic et al.   NEUROPHARMACOLOGY

Widespread sex differences in gene expression and splicing in the adult human brain

(2013) Daniah Trabzuni et al.   Nature Communications

Sex chromosome complement regulates expression of mood-related genes

(2013) Marianne L Seney et al.   Biology of Sex Differences

Sex Differences in the Human Brain and the Impact of Sex Chromosomes and Sex Hormones

(2012) E. Lentini et al.   CEREBRAL CORTEX

Sex Differences in the Brain: The Not So Inconvenient Truth

(2012) M. M. McCarthy et al.   JOURNAL OF NEUROSCIENCE

Loss of Correlations among Proteins in Brains of the Ts65Dn Mouse Model of Down Syndrome

(2012) Md. Mahiuddin Ahmed et al.   JOURNAL OF PROTEOME RESEARCH

TRPM2 channel activation following in vitro ischemia contributes to male hippocampal cell death

(2012) S. Verma et al.   NEUROSCIENCE LETTERS

Target-Derived Matricryptins Organize Cerebellar Synapse Formation through α3β1 Integrins

(2012) Jianmin Su et al.   Cell Reports

Mouse Models of Down Syndrome as a Tool to Unravel the Causes of Mental Disabilities

(2012) Noemí Rueda et al.   NEURAL PLASTICITY

Mitochondrial dysfunction and Down's syndrome: Is there a role for coenzyme Q10?

(2011) Luca Tiano et al.   BIOFACTORS

Genes that escape from X inactivation

(2011) Joel B. Berletch et al.   HUMAN GENETICS

Requirement of the RNA-editing Enzyme ADAR2 for Normal Physiology in Mice

(2011) Marion Horsch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sex Differences in Neuroprotection Provided by Inhibition of TRPM2 Channels following Experimental Stroke

(2011) Jia Jia et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Transcript catalogs of human chromosome 21 and orthologous chimpanzee and mouse regions

(2011) Xiaolu Sturgeon et al.   MAMMALIAN GENOME

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Fyn knock-down increases Aβ, decreases phospho-tau, and worsens spatial learning in 3×Tg-AD mice

(2011) S. Sakura Minami et al.   NEUROBIOLOGY OF AGING

Gender specific requirement of GluR1 receptors in contextual conditioning but not spatial learning

(2011) James Dachtler et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Dependence of NMDA/GSK-3β Mediated Metaplasticity on TRPM2 Channels at Hippocampal CA3-CA1 Synapses

(2011) Yu-Feng Xie et al.   Molecular Brain

Widespread Proliferation Impairment and Hypocellularity in the Cerebellum of Fetuses with Down Syndrome

(2010) Sandra Guidi et al.   BRAIN PATHOLOGY

Endostatin binds nerve growth factor and thereby inhibits neurite outgrowth and neuronal migration in-vitro

(2010) Abraham Al Ahmad et al.   BRAIN RESEARCH

Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice

(2010) Tao Yu et al.   BRAIN RESEARCH

Sexual Dimorphism in Mammalian Autosomal Gene Regulation Is Determined Not Only by Sry but by Sex Chromosome Complement As Well

(2010) Patrick J. Wijchers et al.   DEVELOPMENTAL CELL

Global survey of escape from X inactivation by RNA-sequencing in mouse

(2010) F. Yang et al.   GENOME RESEARCH

A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions

(2010) Tao Yu et al.   HUMAN MOLECULAR GENETICS

Development and validation of the Arizona Cognitive Test Battery for Down syndrome

(2010) Jamie O. Edgin et al.   Journal of Neurodevelopmental Disorders

The Prefrontal Cortex Communicates with the Amygdala to Impair Learning after Acute Stress in Females but Not in Males

(2010) L. Y. Maeng et al.   JOURNAL OF NEUROSCIENCE

Early Pharmacotherapy Restores Neurogenesis and Cognitive Performance in the Ts65Dn Mouse Model for Down Syndrome

(2010) P. Bianchi et al.   JOURNAL OF NEUROSCIENCE

Sex Differences in the Brain, Behavior, and Neuropsychiatric Disorders

(2010) Ai-Min Bao et al.   NEUROSCIENTIST

The roles of phospholipase C activation and alternative ADAR1 and ADAR2 pre-mRNA splicing in modulating serotonin 2C-receptor editing in vivo

(2010) C. Schmauss et al.   RNA

Sex differences in molecular neuroscience: from fruit flies to humans

(2009) Elena Jazin et al.   NATURE REVIEWS NEUROSCIENCE

Twenty-year trends in prevalence and survival of Down syndrome

(2008) Claire Irving et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

RNA editing as a therapeutic target for CNS disorders

(2008) Michael V Morabito et al.   NEUROPSYCHOPHARMACOLOGY