Mitochondrial dysfunction and Down's syndrome: Is there a role for coenzyme Q10?

Evaluation of urinary biomarkers of oxidative/nitrosative stress in adolescents and adults with Down syndrome

(2011) Carlos Campos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Two key genes closely implicated with the neuropathological characteristics in Down syndrome: DYRK1A and RCAN1

(2011) Joong-Kyu Park et al.   BMB Reports

Elevated intracellular calcium causes distinct mitochondrial remodelling and calcineurin-dependent fission in astrocytes

(2011) Andrew R. Tan et al.   CELL CALCIUM

The role of mitochondrial DNA damage in the citotoxicity of reactive oxygen species

(2011) R. A. P. Costa et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Calcium Binding and Transport by Coenzyme Q

(2011) Ivan Bogeski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Prolonged coenzyme Q10 treatment in Down syndrome patients, effect on DNA oxidation

(2011) Luca Tiano et al.   NEUROBIOLOGY OF AGING

Advances in metal-induced oxidative stress and human disease

(2011) Klaudia Jomova et al.   TOXICOLOGY

Mitochondrial Approaches for Neuroprotection

(2010) Rajnish K. Chaturvedi et al.   Annals of the New York Academy of Sciences

Inhibition of Drp1-dependent mitochondrial fragmentation and apoptosis by a polypeptide antagonist of calcineurin

(2010) G M Cereghetti et al.   CELL DEATH AND DIFFERENTIATION

The role of DYRK1A in neurodegenerative diseases

(2010) Jerzy Wegiel et al.   FEBS Journal

Mitochondrial medicine for neurodegenerative diseases

(2010) Heng Du et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A Role for Thrombospondin-1 Deficits in Astrocyte-Mediated Spine and Synaptic Pathology in Down's Syndrome

(2010) Octavio Garcia et al.   PLoS One

Communication breaks-Down: From neurodevelopment defects to cognitive disabilities in Down syndrome

(2010) Andrea Contestabile et al.   PROGRESS IN NEUROBIOLOGY

Coenzyme Q10and oxidative imbalance in Down syndrome: Biochemical and clinical aspects

(2009) L. Tiano et al.   BIOFACTORS

Function and regulation of Dyrk1A: towards understanding Down syndrome

(2009) Joongkyu Park et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Coenzyme Q10 in Neuromuscular and Neurodegenerative Disorders

(2009) M. Mancuso et al.   CURRENT DRUG TARGETS

Down syndrome critical region 1 enhances the proteolytic cleavage of calcineurin

(2009) Ji-Eun Lee et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

DELAYED ONTOGENESIS IN HUMAN TRISOMY SYNDROMES1

(2009) BERTIL HALL   HEREDITAS

Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease

(2009) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Clinical aspects of coenzyme Q10: An update

(2009) Gian Paolo Littarru et al.   NUTRITION

Therapeutic approaches to mitochondrial dysfunction in Parkinson's disease

(2009) M. Flint Beal   PARKINSONISM & RELATED DISORDERS

Biomarkers of oxidative damage to DNA and repair

(2008) Steffen Loft et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Disease-Specific Induced Pluripotent Stem Cells

(2008) In-Hyun Park et al.   CELL

Coenzyme Q10and vitamin E deficiency in Friedreich’s ataxia: predictor of efficacy of vitamin E and coenzyme Q10therapy

(2008) J. M. Cooper et al.   EUROPEAN JOURNAL OF NEUROLOGY

Coenzyme Q10 Attenuates β-Amyloid Pathology in the Aged Transgenic Mice with Alzheimer Presenilin 1 Mutation

(2008) Xifei Yang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Mitochondrial alterations in Parkinson’s disease: new clues

(2008) Miquel Vila et al.   JOURNAL OF NEUROCHEMISTRY

Short-term effects of coenzyme Q10 in progressive supranuclear palsy: A randomized, placebo-controlled trial

(2008) Maria Stamelou et al.   MOVEMENT DISORDERS

Mitochondrial dysfunction in mouse trisomy 16 brain

(2007) L.L. Bambrick et al.   BRAIN RESEARCH