Genomic HIV RNA Induces Innate Immune Responses through RIG-I-Dependent Sensing of Secondary-Structured RNA

Cytosolic Antiviral RNA Recognition Pathway Activates Caspases 1 and 3

(2014) J. Rintahaka et al.   JOURNAL OF IMMUNOLOGY

Innate Sensing of HIV-Infected Cells

(2011) Alice Lepelley et al.   PLoS Pathogens

Peroxisomes Are Signaling Platforms for Antiviral Innate Immunity

(2010) Evelyn Dixit et al.   CELL

Innate Immune Activation in Primary HIV‐1 Infection

(2010) J. Judy Chang et al.   JOURNAL OF INFECTIOUS DISEASES

Reduction of Immune Activation with Chloroquine Therapy during Chronic HIV Infection

(2010) S. M. Murray et al.   JOURNAL OF VIROLOGY

RIG-I-Mediated Antiviral Signaling Is Inhibited in HIV-1 Infection by a Protease-Mediated Sequestration of RIG-I

(2010) M. Solis et al.   JOURNAL OF VIROLOGY

Early Innate Recognition of Herpes Simplex Virus in Human Primary Macrophages Is Mediated via the MDA5/MAVS-Dependent and MDA5/MAVS/RNA Polymerase III-Independent Pathways

(2010) J. Melchjorsen et al.   JOURNAL OF VIROLOGY

HIV-1 Lentiviral Vector Immunogenicity Is Mediated by Toll-Like Receptor 3 (TLR3) and TLR7

(2010) K. Breckpot et al.   JOURNAL OF VIROLOGY

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

(2010) Nicolas Manel et al.   NATURE

The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1

(2010) Nan Yan et al.   NATURE IMMUNOLOGY

IFI16 is an innate immune sensor for intracellular DNA

(2010) Leonie Unterholzner et al.   NATURE IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Innate immune recognition and activation during HIV infection

(2010) Trine H Mogensen et al.   Retrovirology

Regulation of Adaptive Immunity by the Innate Immune System

(2010) A. Iwasaki et al.   SCIENCE

RNA Polymerase III Detects Cytosolic DNA and Induces Type I Interferons through the RIG-I Pathway

(2009) Yu-Hsin Chiu et al.   CELL

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

(2009) Martin Schlee et al.   IMMUNITY

Human Immunodeficiency Virus Type 1 Mediates Global Disruption of Innate Antiviral Signaling and Immune Defenses within Infected Cells

(2009) B. P. Doehle et al.   JOURNAL OF VIROLOGY

Activation of MDA5 Requires Higher-Order RNA Structures Generated during Virus Infection

(2009) A. Pichlmair et al.   JOURNAL OF VIROLOGY

Architecture and secondary structure of an entire HIV-1 RNA genome

(2009) Joseph M. Watts et al.   NATURE

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III–transcribed RNA intermediate

(2009) Andrea Ablasser et al.   NATURE IMMUNOLOGY

Emerging Concepts in the Immunopathogenesis of AIDS

(2008) Daniel C. Douek et al.   Annual Review of Medicine

Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology

(2008) S. Baenziger et al.   BLOOD

Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity

(2008) Daniel B. Stetson et al.   CELL

The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

(2008) Bo Zhong et al.   IMMUNITY

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5

(2008) Hiroki Kato et al.   JOURNAL OF EXPERIMENTAL MEDICINE

HIV immunology needs a new direction

(2008) Ruslan Medzhitov et al.   NATURE

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

(2008) Hiroki Ishikawa et al.   NATURE

HIV-1 Activates Macrophages Independent of Toll-Like Receptors

(2008) Joseph N. Brown et al.   PLoS One