Novel miRNA-mRNA interactions conserved in essential cancer pathways

MicroRNA-1976 functions as a tumor suppressor and serves as a prognostic indicator in non-small cell lung cancer by directly targeting PLCE1

(2016) Gang Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Positive expression of KIF20A indicates poor prognosis of glioma patients

(2016) Jia Duan et al.   OncoTargets and Therapy

Targeting survivin as a potential new treatment for chondrosarcoma of bone

(2016) Y de Jong et al.   Oncogenesis

miRNA let-7b modulates macrophage polarization and enhances tumor-associated macrophages to promote angiogenesis and mobility in prostate cancer

(2016) Zhigang Wang et al.   Scientific Reports

miARma-Seq: a comprehensive tool for miRNA, mRNA and circRNA analysis

(2016) Eduardo Andrés-León et al.   Scientific Reports

Prognostic value of Aurora kinase A (AURKA) expression among solid tumor patients: a systematic review and meta-analysis

(2015) Jiao Zhang et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Comprehensive genomic characterization of head and neck squamous cell carcinomas

(2015)   NATURE

Pathway and network analysis of cancer genomes

(2015)   NATURE METHODS

KEGG as a reference resource for gene and protein annotation

(2015) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

NCG 5.0: updates of a manually curated repository of cancer genes and associated properties from cancer mutational screenings

(2015) Omer An et al.   NUCLEIC ACIDS RESEARCH

miRTarBase 2016: updates to the experimentally validated miRNA-target interactions database

(2015) Chih-Hung Chou et al.   NUCLEIC ACIDS RESEARCH

The Reactome pathway Knowledgebase

(2015) Antonio Fabregat et al.   NUCLEIC ACIDS RESEARCH

Ensembl 2016

(2015) Andrew Yates et al.   NUCLEIC ACIDS RESEARCH

Genome-wide mRNA and miRNA expression profiling reveal multiple regulatory networks in colorectal cancer

(2015) R Vishnubalaji et al.   Cell Death & Disease

Wanderer, an interactive viewer to explore DNA methylation and gene expression data in human cancer

(2015) Anna Díez-Villanueva et al.   Epigenetics & Chromatin

Pan-cancer stratification of solid human epithelial tumors and cancer cell lines reveals commonalities and tissue-specific features of the CpG island methylator phenotype

(2015) Francisco Sánchez-Vega et al.   Epigenetics & Chromatin

miRGate: a curated database of human, mouse and rat miRNA–mRNA targets

(2015) Eduardo Andrés-León et al.   Database-The Journal of Biological Databases and Curation

Elevated expression of UBE2T exhibits oncogenic properties in human prostate cancer

(2015) Mingxin Wen et al.   Oncotarget

An integrative pan-cancer-wide analysis of epigenetic enzymes reveals universal patterns of epigenomic deregulation in cancer

(2015) Zhen Yang et al.   GENOME BIOLOGY

Overexpression of centromere protein K (CENPK) in ovarian cancer is correlated with poor patient survival and associated with predictive and prognostic relevance

(2015) Yi-Chao Lee et al.   PeerJ

OncomiRDB: a database for the experimentally verified oncogenic and tumor-suppressive microRNAs

(2014) Dongfang Wang et al.   BIOINFORMATICS

Cdc20 and securin overexpression predict short-term breast cancer survival

(2014) H Karra et al.   BRITISH JOURNAL OF CANCER

let-7b/g silencing activates AKT signaling to promote gastric carcinogenesis

(2014) Wei Kang et al.   Journal of Translational Medicine

Emergence and Evolutionary Analysis of the Human DDR Network: Implications in Comparative Genomics and Downstream Analyses

(2014) Aida Arcas et al.   MOLECULAR BIOLOGY AND EVOLUTION

Kinetochore genes are coordinately up-regulated in human tumors as part of a FoxM1-related cell division program

(2014) Prathapan Thiru et al.   MOLECULAR BIOLOGY OF THE CELL

Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes

(2014) Mark D M Leiserson et al.   NATURE GENETICS

COSMIC: exploring the world's knowledge of somatic mutations in human cancer

(2014) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Integrated microRNA and mRNA Transcriptome Sequencing Reveals the Potential Roles of miRNAs in Stage I Endometrioid Endometrial Carcinoma

(2014) Hanzhen Xiong et al.   PLoS One

Potential microRNA-mediated oncogenic intercellular communication revealed by pan-cancer analysis

(2014) Yue Li et al.   Scientific Reports

miRCancer: a microRNA-cancer association database constructed by text mining on literature

(2013) B. Xie et al.   BIOINFORMATICS

Aurora kinase A (AURKA) expression in colorectal cancer liver metastasis is associated with poor prognosis

(2013) J A C M Goos et al.   BRITISH JOURNAL OF CANCER

BRCA1 expression and improved survival in ovarian cancer patients treated with intraperitoneal cisplatin and paclitaxel: a Gynecologic Oncology Group Study

(2013) J L Lesnock et al.   BRITISH JOURNAL OF CANCER

Transcriptional Regulation and Its Misregulation in Disease

(2013) Tong Ihn Lee et al.   CELL

Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding

(2013) Aleksandra Helwak et al.   CELL

CDC20 overexpression predicts a poor prognosis for patients with colorectal cancer

(2013) Wen-jing Wu et al.   Journal of Translational Medicine

Prognostic significance of let-7b expression in breast cancer and correlation to its target gene of BSG expression

(2013) Lin Ma et al.   MEDICAL ONCOLOGY

Comprehensive molecular characterization of clear cell renal cell carcinoma

(2013)   NATURE

Count-based differential expression analysis of RNA sequencing data using R and Bioconductor

(2013) Simon Anders et al.   Nature Protocols

Analysis of microRNA-target interactions across diverse cancer types

(2013) Anders Jacobsen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

miRBase: annotating high confidence microRNAs using deep sequencing data

(2013) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

Expression of aurora kinase A is associated with metastasis-free survival in node-negative breast cancer patients

(2012) Wulf Siggelkow et al.   BMC CANCER

DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis

(2012) Wynand P. Roos et al.   CANCER LETTERS

Identification of MicroRNAs associated with early relapse after nephrectomy in renal cell carcinoma patients

(2012) Ondrej Slaby et al.   GENES CHROMOSOMES & CANCER

let-7b and miR-126 Are Down-Regulated in Tumor Tissue and Correlate with Microvessel Density and Survival Outcomes in Non–Small–Cell Lung Cancer

(2012) Edin Jusufović et al.   PLoS One

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Cell cycle and aging, morphogenesis, and response to stimuli genes are individualized biomarkers of glioblastoma progression and survival

(2011) Nicola VL Serão et al.   BMC Medical Genomics

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers

(2011) Craig H Mermel et al.   GENOME BIOLOGY

Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

(2010) Pan Du et al.   BMC BIOINFORMATICS

ESR1/SYNE1 Polymorphism and Invasive Epithelial Ovarian Cancer Risk: An Ovarian Cancer Association Consortium Study

(2010) J. A. Doherty et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Got target?: computational methods for microRNA target prediction and their extension

(2010) Hyeyoung Min et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Differential expression of microRNA species in human gastric cancer versus non-tumorous tissues

(2008) Junming Guo et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE

MicroRNA-373 induces expression of genes with complementary promoter sequences

(2008) R. F. Place et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA