Emergence and Evolutionary Analysis of the Human DDR Network: Implications in Comparative Genomics and Downstream Analyses

Serine/threonine kinases and E2-ubiquitin conjugating enzymes in Planctomycetes: unexpected findings

(2013) Aida Arcas et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

SIRT1 Negatively Regulates the Activities, Functions, and Protein Levels of hMOF and TIP60

(2012) L. Peng et al.   MOLECULAR AND CELLULAR BIOLOGY

Ensembl 2013

(2012) Paul Flicek et al.   NUCLEIC ACIDS RESEARCH

ProteinHistorian: Tools for the Comparative Analysis of Eukaryote Protein Origin

(2012) John A. Capra et al.   PLoS Computational Biology

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

(2011) Jiri Lukas et al.   NATURE CELL BIOLOGY

A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations

(2011) Luis I Toledo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

More forks on the road to replication stress recovery

(2011) C. Allen et al.   Journal of Molecular Cell Biology

Count: evolutionary analysis of phylogenetic profiles with parsimony and likelihood

(2010) M. Csuos   BIOINFORMATICS

53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

(2010) Samuel F. Bunting et al.   CELL

TRF2 and Apollo Cooperate with Topoisomerase 2α to Protect Human Telomeres from Replicative Damage

(2010) Jing Ye et al.   CELL

Sensitivity to Poly(ADP-ribose) Polymerase (PARP) Inhibition Identifies Ubiquitin-specific Peptidase 11 (USP11) as a Regulator of DNA Double-strand Break Repair

(2010) Timothy D. Wiltshire et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functions and Regulation of Artemis: A Goddess in the Maintenance of Genome Integrity

(2010) Aya KUROSAWA et al.   JOURNAL OF RADIATION RESEARCH

MOF and Histone H4 Acetylation at Lysine 16 Are Critical for DNA Damage Response and Double-Strand Break Repair

(2010) G. G. Sharma et al.   MOLECULAR AND CELLULAR BIOLOGY

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C

(2010) M. Ming et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An end-joining repair mechanism in Escherichia coli

(2010) R. Chayot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint

(2010) Marcel A. T. M. van Vugt et al.   PLOS BIOLOGY

Functional Organization of the S. cerevisiae Phosphorylation Network

(2009) Dorothea Fiedler et al.   CELL

Human SLX4 Is a Holliday Junction Resolvase Subunit that Binds Multiple DNA Repair/Recombination Endonucleases

(2009) Samira Fekairi et al.   CELL

Evolution: Revisiting the Root of the Eukaryote Tree

(2009) Andrew J. Roger et al.   CURRENT BIOLOGY

Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2

(2009) H Christian Reinhardt et al.   CURRENT OPINION IN CELL BIOLOGY

Regulatory ubiquitylation in response to DNA double-strand breaks

(2009) Stephanie Panier et al.   DNA REPAIR

Taking the time to make important decisions: The checkpoint effector kinases Chk1 and Chk2 and the DNA damage response

(2009) Travis H. Stracker et al.   DNA REPAIR

53BP1 promotes ATM activity through direct interactions with the MRN complex

(2009) Ji-Hoon Lee et al.   EMBO JOURNAL

Intrauterine programming of ageing

(2009) Oscar Fernandez-Capetillo   EMBO REPORTS

MERIT40 facilitates BRCA1 localization and DNA damage repair

(2009) L. Feng et al.   GENES & DEVELOPMENT

The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forks

(2009) C. E. Bansbach et al.   GENES & DEVELOPMENT

The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress

(2009) Joanna R. Morris et al.   NATURE

Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks

(2009) Yaron Galanty et al.   NATURE

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage

(2009) Manas K. Santra et al.   NATURE

TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs

(2009) Hyeung Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The universal distribution of evolutionary rates of genes and distinct characteristics of eukaryotic genes of different apparent ages

(2009) Y. I. Wolf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

When it comes to homology, bad habits die hard

(2009) Anna Marabotti et al.   TRENDS IN BIOCHEMICAL SCIENCES

Transcription-coupled nucleotide excision repair in mammalian cells: molecular mechanisms and biological effects

(2008) Maria Fousteri et al.   CELL RESEARCH

Genetic analysis of CHK1 and CHK2 homologues revealed a unique cross talk between ATM and ATR pathways in Neurospora crassa

(2008) Michiyoshi Wakabayashi et al.   DNA REPAIR

BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome

(2008) T. R. Singh et al.   GENES & DEVELOPMENT

The Trichoplax genome and the nature of placozoans

(2008) Mansi Srivastava et al.   NATURE

Horizontal gene transfer in eukaryotic evolution

(2008) Patrick J. Keeling et al.   NATURE REVIEWS GENETICS

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Snm1B/Apollo mediates replication fork collapse and S Phase checkpoint activation in response to DNA interstrand cross-links

(2008) J-B Bae et al.   ONCOGENE

Alignment Uncertainty and Genomic Analysis

(2008) K. M. Wong et al.   SCIENCE

The Neurospora crassa UVS-3 epistasis group encodes homologues of the ATR/ATRIP checkpoint control system

(2007) Yusuke Kazama et al.   DNA REPAIR