Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer’s model mice

Cardiolipin Profile Changes are Associated to the Early Synaptic Mitochondrial Dysfunction in Alzheimer's Disease

(2018) Vera F. Monteiro-Cardoso et al.   JOURNAL OF ALZHEIMERS DISEASE

Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease

(2017) Taylor R. Jay et al.   JOURNAL OF NEUROSCIENCE

Modifiable Risk Factors and Brain Positron Emission Tomography Measures of Amyloid and Tau in Nondemented Adults with Memory Complaints

(2016) David A. Merrill et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Mitochondrial DNA Depletion in Respiratory Chain-Deficient Parkinson Disease Neurons

(2016) Anne Grünewald et al.   ANNALS OF NEUROLOGY

Exposure of phosphatidylserine on the cell surface

(2016) S Nagata et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation

(2016) Noga Ron-Harel et al.   Cell Metabolism

Evaluation of Neuropathological Effects of a High-Fat Diet in a Presymptomatic Alzheimer’s Disease Stage in APP/PS1 Mice

(2016) Miren Ettcheto et al.   JOURNAL OF ALZHEIMERS DISEASE

A GABAergic Projection from the Centromedial Nuclei of the Amygdala to Ventromedial Prefrontal Cortex Modulates Reward Behavior

(2016) Dong-oh Seo et al.   JOURNAL OF NEUROSCIENCE

Neuron-derived orphan receptor 1 transduces survival signals in neuronal cells in response to hypoxia-induced apoptotic insults

(2016) Chung-Ching Chio et al.   JOURNAL OF NEUROSURGERY

Midlife Work-Related Stress Increases Dementia Risk in Later Life: The CAIDE 30-Year Study

(2016) Shireen Sindi et al.   JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES

Lipidomics Analyses Reveal Temporal and Spatial Lipid Organization and Uncover Daily Oscillations in Intracellular Organelles

(2016) Rona Aviram et al.   MOLECULAR CELL

Genetic variants in Alzheimer disease — molecular and brain network approaches

(2016) Chris Gaiteri et al.   Nature Reviews Neurology

TREM2 variants: new keys to decipher Alzheimer disease pathogenesis

(2016) Marco Colonna et al.   NATURE REVIEWS NEUROSCIENCE

The Effect of a High-Fat Diet on Brain Plasticity, Inflammation and Cognition in Female ApoE4-Knockin and ApoE-Knockout Mice

(2016) Carola I. F. Janssen et al.   PLoS One

Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer’s disease

(2016) Leah C. Graham et al.   Scientific Reports

Increased Aβ pathology in aged Tg2576 mice born to mothers fed a high fat diet

(2016) Shereen Nizari et al.   Scientific Reports

RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers

(2016) Kyong Nyon Nam et al.   Scientific Reports

High‐Fat‐Diet Intake Enhances Cerebral Amyloid Angiopathy and Cognitive Impairment in a Mouse Model of Alzheimer's Disease, Independently of Metabolic Disorders

(2016) Bowen Lin et al.   Journal of the American Heart Association

The Enemy within: Innate Surveillance-Mediated Cell Death, the Common Mechanism of Neurodegenerative Disease

(2016) Robert I. Richards et al.   Frontiers in Neuroscience

High-Fat Diet Changes Hippocampal Apolipoprotein E (ApoE) in a Genotype- and Carbohydrate-Dependent Manner in Mice

(2016) Courtney Lane-Donovan et al.   PLoS One

PI3K signalling in inflammation

(2015) P.T. Hawkins et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Opposing effects ofApoe/Apoa1double deletion on amyloid-β pathology and cognitive performance in APP mice

(2015) Nicholas F. Fitz et al.   BRAIN

TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model

(2015) Yaming Wang et al.   CELL

The GABA Transaminase, ABAT, Is Essential for Mitochondrial Nucleoside Metabolism

(2015) Arnaud Besse et al.   Cell Metabolism

Alzheimer's disease: rare variants with large effect sizes

(2015) Jorge L Del-Aguila et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

How lipids modulate mitochondrial protein import

(2015) Lena Böttinger et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1

(2015) Aaron M. Fond et al.   JOURNAL OF CLINICAL INVESTIGATION

TREM2 deficiency eliminates TREM2+inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models

(2015) Taylor R. Jay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Nuclear Receptors License Phagocytosis by Trem2+ Myeloid Cells in Mouse Models of Alzheimer's Disease

(2015) J. C. Savage et al.   JOURNAL OF NEUROSCIENCE

A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial

(2015) Tiia Ngandu et al.   LANCET

RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment

(2015) Iliya Lefterov et al.   NEUROBIOLOGY OF DISEASE

Dichotomous roles for externalized cardiolipin in extracellular signaling: Promotion of phagocytosis and attenuation of innate immunity

(2015) Krishnakumar Balasubramanian et al.   Science Signaling

Dichotomous roles for externalized cardiolipin in extracellular signaling: Promotion of phagocytosis and attenuation of innate immunity

(2015) Krishnakumar Balasubramanian et al.   Science Signaling

Disorders of phospholipid metabolism: an emerging class of mitochondrial disease due to defects in nuclear genes

(2015) Ya-Wen Lu et al.   Frontiers in Genetics

Oxidatively modified phosphatidylserines on the surface of apoptotic cells are essential phagocytic ‘eat-me’ signals: cleavage and inhibition of phagocytosis by Lp-PLA2

(2014) V A Tyurin et al.   CELL DEATH AND DIFFERENTIATION

Vesicular Glutamate Transporter Expression Level Affects Synaptic Vesicle Release Probability at Hippocampal Synapses in Culture

(2014) M. A. Herman et al.   JOURNAL OF NEUROSCIENCE

A mitochondrial pathway for biosynthesis of lipid mediators

(2014) Yulia Y. Tyurina et al.   Nature Chemistry

Genetics of Alzheimer’s Disease

(2014) Rita Guerreiro et al.   Neurotherapeutics

Contribution of Defective PS Recognition and Efferocytosis to Chronic Inflammation and Autoimmunity

(2014) Stanley Gititu Kimani et al.   Frontiers in Immunology

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

NR4A nuclear receptors in immunity and atherosclerosis

(2013) Anouk A.J. Hamers et al.   CURRENT OPINION IN LIPIDOLOGY

The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity

(2013) Zaida G Ramirez-Ortiz et al.   NATURE IMMUNOLOGY

Effects of a high-fat, high-cholesterol diet on brain lipid profiles in apolipoprotein E ɛ3 and ɛ4 knock-in mice

(2013) Wei Ling Florence Lim et al.   NEUROBIOLOGY OF AGING

The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote

(2013) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

Mice Deficient in the Respiratory Chain Gene Cox6a2 Are Protected against High-Fat Diet-Induced Obesity and Insulin Resistance

(2013) Roel Quintens et al.   PLoS One

Midlife vascular risk factors and their association with dementia deaths: Results from a Norwegian prospective study followed up for 35years

(2012) Bjørn Heine Strand et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial Injury after Mechanical Stretch of Cortical Neurons in vitro: Biomarkers of Apoptosis and Selective Peroxidation of Anionic Phospholipids

(2011) Jing Ji et al.   JOURNAL OF NEUROTRAUMA

Multi-dimensional mass spectrometry-based shotgun lipidomics and novel strategies for lipidomic analyses

(2011) Xianlin Han et al.   MASS SPECTROMETRY REVIEWS

Postnatal loss of Dlk1 imprinting in stem cells and niche astrocytes regulates neurogenesis

(2011) Sacri R. Ferrón et al.   NATURE

Flippin' lipids

(2011) Marcus R Clark   NATURE IMMUNOLOGY

Metabolomics in Early Alzheimer's Disease: Identification of Altered Plasma Sphingolipidome Using Shotgun Lipidomics

(2011) Xianlin Han et al.   PLoS One

Dysregulation of Kruppel-like factor 4 during brain development leads to hydrocephalus in mice

(2011) S. Qin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The complexity of cardiolipin in health and disease

(2011) Steven M. Claypool et al.   TRENDS IN BIOCHEMICAL SCIENCES

Liver X Receptor Agonist Treatment Ameliorates Amyloid Pathology and Memory Deficits Caused by High-Fat Diet in APP23 Mice

(2010) N. F. Fitz et al.   JOURNAL OF NEUROSCIENCE

Automated Lipid Identification and Quantification by Multidimensional Mass Spectrometry-Based Shotgun Lipidomics

(2009) Kui Yang et al.   ANALYTICAL CHEMISTRY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

KLF Family Members Regulate Intrinsic Axon Regeneration Ability

(2009) D. L. Moore et al.   SCIENCE

Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors

(2008) Raj N Kalaria et al.   LANCET NEUROLOGY