A Viral Vectored Prime-Boost Immunization Regime Targeting the Malaria Pfs25 Antigen Induces Transmission-Blocking Activity

A Plant-Produced Pfs230 Vaccine Candidate Blocks Transmission of Plasmodium falciparum

(2011) Christine E. Farrance et al.   Clinical and Vaccine Immunology

Antibodies to plant-producedPlasmodium falciparumsexual stage protein Pfs25 exhibit transmission blocking activity

(2011) Christine E. Farrance et al.   Human vaccines & immunotherapeutics

The Requirement for Potent Adjuvants To Enhance the Immunogenicity and Protective Efficacy of Protein Vaccines Can Be Overcome by Prior Immunization with a Recombinant Adenovirus

(2011) S. C. de Cassan et al.   JOURNAL OF IMMUNOLOGY

Combining Liver- and Blood-Stage Malaria Viral-Vectored Vaccines: Investigating Mechanisms of CD8+ T Cell Interference

(2011) E. K. Forbes et al.   JOURNAL OF IMMUNOLOGY

Transgene Optimization, Immunogenicity and In Vitro Efficacy of Viral Vectored Vaccines Expressing Two Alleles of Plasmodium falciparum AMA1

(2011) Sumi Biswas et al.   PLoS One

Adenovirus-vectored Plasmodium vivax ookinete surface protein, Pvs25, as a potential transmission-blocking vaccine

(2011) Takeshi Miyata et al.   VACCINE

Blood-stage malaria vaccines — recent progress and future challenges

(2010) A. L. Goodman et al.   ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY

A biologist’s perspective on malaria vaccine development

(2010) Robert Sinden   Human vaccines & immunotherapeutics

Prime-boost vectored malaria vaccines: Progress and prospects

(2010) Adrian V. S. Hill et al.   Human vaccines & immunotherapeutics

New Candidate Vaccines against Blood-Stage Plasmodium falciparum Malaria: Prime-Boost Immunization Regimens Incorporating Human and Simian Adenoviral Vectors and Poxviral Vectors Expressing an Optimized Antigen Based on Merozoite Surface Protein 1

(2010) A. L. Goodman et al.   INFECTION AND IMMUNITY

Enhancing Blood-Stage Malaria Subunit Vaccine Immunogenicity in Rhesus Macaques by Combining Adenovirus, Poxvirus, and Protein-in-Adjuvant Vaccines

(2010) S. J. Draper et al.   JOURNAL OF IMMUNOLOGY

The IC50 of anti-Pfs25 antibody in membrane-feeding assay varies among species

(2010) Lediya Cheru et al.   VACCINE

Intranasal and intramuscular immunization with Baculovirus Dual Expression System-based Pvs25 vaccine substantially blocks Plasmodium vivax transmission

(2010) Andrew M. Blagborough et al.   VACCINE

Functional immunogenicity of baculovirus expressing Pfs25, a human malaria transmission-blocking vaccine candidate antigen

(2010) Godfree Mlambo et al.   VACCINE

Tailoring subunit vaccine immunogenicity: Maximizing antibody and T cell responses by using combinations of adenovirus, poxvirus and protein-adjuvant vaccines against Plasmodium falciparum MSP1

(2010) Alexander D. Douglas et al.   VACCINE

The RTS,S malaria vaccine

(2010) Sofia Casares et al.   VACCINE

Recombinant Viral Vaccines Expressing Merozoite Surface Protein-1 Induce Antibody- and T Cell-Mediated Multistage Protection against Malaria

(2009) Simon J. Draper et al.   Cell Host & Microbe

Malaria Ookinete Surface Protein-Based Vaccination via the Intranasal Route Completely Blocks Parasite Transmission in both Passive and Active Vaccination Regimens in a Rodent Model of Malaria Infection

(2009) T. Arakawa et al.   INFECTION AND IMMUNITY

Analysis of Immunity to Febrile Malaria in Children That Distinguishes Immunity from Lack of Exposure

(2009) P. Bejon et al.   INFECTION AND IMMUNITY

Initiative targets malaria eradication

(2009) Declan Butler   NATURE

Viruses as vaccine vectors for infectious diseases and cancer

(2009) Simon J. Draper et al.   NATURE REVIEWS MICROBIOLOGY

Plasmodium berghei HAP2 induces strong malaria transmission-blocking immunity in vivo and in vitro

(2009) Andrew M. Blagborough et al.   VACCINE

Transgenic RodentPlasmodium bergheiParasites as Tools for Assessment of Functional Immunogenicity and Optimization of Human Malaria Vaccines

(2008) Godfree Mlambo et al.   EUKARYOTIC CELL

Murine Model for Assessment of Plasmodium falciparum Transmission-Blocking Vaccine Using Transgenic Plasmodium berghei Parasites Expressing the Target Antigen Pfs25

(2008) G. Mlambo et al.   INFECTION AND IMMUNITY

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET

Evaluation and optimization of membrane feeding compared to direct feeding as an assay for infectivity

(2008) Mouctar Diallo et al.   MALARIA JOURNAL

Effective induction of high-titer antibodies by viral vector vaccines

(2008) Simon J Draper et al.   NATURE MEDICINE

Phase 1 Trial of Malaria Transmission Blocking Vaccine Candidates Pfs25 and Pvs25 Formulated with Montanide ISA 51

(2008) Yimin Wu et al.   PLoS One

Addition of CpG ODN to recombinant Pseudomonas aeruginosa ExoProtein A conjugates of AMA1 and Pfs25 greatly increases the number of responders

(2008) Feng Qian et al.   VACCINE

Development and characterization of a standardized ELISA including a reference serum on each plate to detect antibodies induced by experimental malaria vaccines

(2007) Kazutoyo Miura et al.   VACCINE

Markedly enhanced immunogenicity of a Pfs25 DNA-based malaria transmission-blocking vaccine by in vivo electroporation

(2007) Ralph LeBlanc et al.   VACCINE