Quality and quantity of T FH cells are critical for broad antibody development in SHIV AD8 infection

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Single-Cell and Deep Sequencing of IgG-Switched Macaque B Cells Reveal a Diverse Ig Repertoire following Immunization

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Loss of Circulating CD4 T Cells with B Cell Helper Function during Chronic HIV Infection

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Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection

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Persistent Antigen and Germinal Center B Cells Sustain T Follicular Helper Cell Responses and Phenotype

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Circulating Precursor CCR7loPD-1hi CXCR5+ CD4+ T Cells Indicate Tfh Cell Activity and Promote Antibody Responses upon Antigen Reexposure

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Human Circulating PD-1+CXCR3−CXCR5+ Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses

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HIV-1 neutralizing antibodies: understanding nature's pathways

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Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

(2013) Hua-Xin Liao et al.   NATURE

Inadequate T follicular cell help impairs B cell immunity during HIV infection

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Human circulating influenza-CD4+ ICOS1+IL-21+ T cells expand after vaccination, exert helper function, and predict antibody responses

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Delineating Antibody Recognition in Polyclonal Sera from Patterns of HIV-1 Isolate Neutralization

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T Follicular Helper Cell Dynamics in Germinal Centers

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Induction of ICOS+CXCR3+CXCR5+ TH Cells Correlates with Antibody Responses to Influenza Vaccination

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Somatic populations of PGT135–137 HIV-1-neutralizing antibodies identified by 454 pyrosequencing and bioinformatic

(2013) Jiang Zhu   Frontiers in Microbiology

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Expansion of HIV-specific T follicular helper cells in chronic HIV infection

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CD4 T follicular helper cell dynamics during SIV infection

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Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production

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Isolation of antibody V(D)J sequences from single cell sorted rhesus macaque B cells

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Pathogenicity and Mucosal Transmissibility of the R5-Tropic Simian/Human Immunodeficiency Virus SHIVAD8in Rhesus Macaques: Implications for Use in Vaccine Studies

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Most rhesus macaques infected with the CCR5-tropic SHIVAD8 generate cross-reactive antibodies that neutralize multiple HIV-1 strains

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Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells

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Plasma Levels of Soluble CD14 Independently Predict Mortality in HIV Infection

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Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque

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Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

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Late Interleukin-6 Escalates T Follicular Helper Cell Responses and Controls a Chronic Viral Infection

(2011) J. A. Harker et al.   SCIENCE

Characteristics of the Earliest Cross-Neutralizing Antibody Response to HIV-1

(2011) Iliyana Mikell et al.   PLoS Pathogens

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

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Follicular Helper T Cells: Lineage and Location

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The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment

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Tiered Categorization of a Diverse Panel of HIV-1 Env Pseudoviruses for Assessment of Neutralizing Antibodies

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Breadth of Human Immunodeficiency Virus-Specific Neutralizing Activity in Sera: Clustering Analysis and Association with Clinical Variables

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Breadth of Neutralizing Antibody Response to Human Immunodeficiency Virus Type 1 Is Affected by Factors Early in Infection but Does Not Influence Disease Progression

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Cytokine-secreting follicular T cells shape the antibody repertoire

(2009) R Lee Reinhardt et al.   NATURE IMMUNOLOGY

Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?

(2009) Leonidas Stamatatos et al.   NATURE MEDICINE

Bcl6 Mediates the Development of T Follicular Helper Cells

(2009) R. I. Nurieva et al.   SCIENCE

Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages

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A method for identification of HIV gp140 binding memory B cells in human blood

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Factors Associated with the Development of Cross-Reactive Neutralizing Antibodies during Human Immunodeficiency Virus Type 1 Infection

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IMGT(R), the international ImMunoGeneTics information system(R)

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