A Modular Vaccine Development Platform Based on Sortase-Mediated Site-Specific Tagging of Antigens onto Virus-Like Particles

Genetically Improved Monolayer-Forming Tobacco Mosaic Viruses to Generate Nanostructured Semiconducting Bio/Inorganic Hybrids

(2015) Petia Atanasova et al.   LANGMUIR

Site-specific protein modification using immobilized sortase in batch and continuous-flow systems

(2015) Martin D Witte et al.   Nature Protocols

Depsipeptide substrates for sortase-mediated N-terminal protein ligation

(2014) Daniel J Williamson et al.   Nature Protocols

Aβ-HBc virus-like particles immunization without additional adjuvant ameliorates the learning and memory and reduces Aβ deposit in PDAPP mice

(2014) Hui Jin et al.   VACCINE

Biomimetic Protein Nanoparticles Facilitate Enhanced Dendritic Cell Activation and Cross-Presentation

(2013) Nicholas M. Molino et al.   ACS Nano

Characterization of a Discontinuous Neutralizing Epitope on Glycoprotein B of Human Cytomegalovirus

(2013) N. Spindler et al.   JOURNAL OF VIROLOGY

Chimeric Virus-Like Particle Vaccines Displaying Conserved Enterovirus 71 Epitopes Elicit Protective Neutralizing Antibodies in Mice through Divergent Mechanisms

(2013) X. Ye et al.   JOURNAL OF VIROLOGY

Site-specific C-terminal and internal loop labeling of proteins using sortase-mediated reactions

(2013) Carla P Guimaraes et al.   Nature Protocols

Sortase-mediated modification of αDEC205 affords optimization of antigen presentation and immunization against a set of viral epitopes

(2013) Lee Kim Swee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Native agarose gel electrophoresis and electroelution: A fast and cost-effective method to separate the small and large hepatitis B capsids

(2012) Kam Yee Yoon et al.   ELECTROPHORESIS

Cell-Specific Delivery of Diverse Cargos by Bacteriophage MS2 Virus-like Particles

(2011) Carlee E. Ashley et al.   ACS Nano

Aptamer-Modified Nanodrug Delivery Systems

(2011) Zhan Wu et al.   ACS Nano

Surface Functionalization of Virus-Like Particles by Direct Conjugation Using Azide−Alkyne Click Chemistry

(2011) Kedar G. Patel et al.   BIOCONJUGATE CHEMISTRY

Multivalent Display of Proteins on Viral Nanoparticles Using Molecular Recognition and Chemical Ligation Strategies

(2011) P. Arno Venter et al.   BIOMACROMOLECULES

Catalytic Mechanism and Roles of Arg197 and Thr183 in theStaphylococcus aureusSortase A Enzyme

(2011) Bo-Xue Tian et al.   JOURNAL OF PHYSICAL CHEMISTRY B

A general strategy for the evolution of bond-forming enzymes using yeast display

(2011) I. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SplitCore: An exceptionally versatile viral nanoparticle for native whole protein display regardless of 3D structure

(2011) Andreas Walker et al.   Scientific Reports

B Cell Repertoire Analysis Identifies New Antigenic Domains on Glycoprotein B of Human Cytomegalovirus which Are Target of Neutralizing Antibodies

(2011) Sonja Pötzsch et al.   PLoS Pathogens

Generation of a tumor vaccine candidate based on conjugation of a MUC1 peptide to polyionic papillomavirus virus-like particles

(2010) Sharmila Pejawar-Gaddy et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Memory and Effector CD8 T-cell Responses After Nanoparticle Vaccination of Melanoma Patients

(2010) Daniel E. Speiser et al.   JOURNAL OF IMMUNOTHERAPY

Viral nanoparticles and virus-like particles: platforms for contemporary vaccine design

(2010) Emily M. Plummer et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Melanoma vaccine candidates from chimeric hepatitis B core virus-like particles carrying a tumor-associated MAGE-3 epitope

(2008) Andris Kazaks et al.   Biotechnology Journal

Active immunization with IL-1 displayed on virus-like particles protects from autoimmune arthritis

(2008) Gunther Spohn et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Phase I Trial of an Alhydrogel Adjuvanted Hepatitis B Core Virus-Like Particle Containing Epitopes of Plasmodium falciparum Circumsporozoite Protein

(2008) Aric L. Gregson et al.   PLoS One

Chimeric hepatitis B virus core particles carrying an epitope of anthrax protective antigen induce protective immunity against Bacillus anthracis

(2008) Ying Yin et al.   VACCINE