Exome Sequencing Identifies Potentially Druggable Mutations in Nasopharyngeal Carcinoma
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Title
Exome Sequencing Identifies Potentially Druggable Mutations in Nasopharyngeal Carcinoma
Authors
Keywords
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Journal
Scientific Reports
Volume 7, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-03-03
DOI
10.1038/srep42980
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Note: Only part of the references are listed.- Toxicity and efficacy of cetuximab associated with several modalities of IMRT for locally advanced head and neck cancer
- (2016) J.-E. Bibault et al. Cancer Radiotherapie
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- (2016) J. A. Guadarrama-Orozco et al. Clinical & Translational Oncology
- TP53 and MDM2 genetic alterations in non-small cell lung cancer: Evaluating their prognostic and predictive value
- (2016) Christophe Deben et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- The possibility of clinical sequencing in the management of cancer
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- Five-Year Survival in EGFR -Mutant Metastatic Lung Adenocarcinoma Treated with EGFR-TKIs
- (2016) Jessica J. Lin et al. Journal of Thoracic Oncology
- A new generation of cancer genome diagnostics for routine clinical use: overcoming the roadblocks to personalized cancer medicine
- (2015) J. M. Heuckmann et al. ANNALS OF ONCOLOGY
- Translating cancer genomes and transcriptomes for precision oncology
- (2015) Sameek Roychowdhury et al. CA-A CANCER JOURNAL FOR CLINICIANS
- FDA Approval Summary: Olaparib Monotherapy in Patients with Deleterious Germline BRCA-Mutated Advanced Ovarian Cancer Treated with Three or More Lines of Chemotherapy
- (2015) G. Kim et al. CLINICAL CANCER RESEARCH
- Targeting signaling factors for degradation, an emerging mechanism for TRAF functions
- (2015) Xiao-Dong Yang et al. IMMUNOLOGICAL REVIEWS
- Management of Nasopharyngeal Carcinoma: Current Practice and Future Perspective
- (2015) Anne W.M. Lee et al. JOURNAL OF CLINICAL ONCOLOGY
- Massively Parallel Sequencing Identifies Recurrent Mutations in TP53 in Thymic Carcinoma Associated with Poor Prognosis
- (2015) Andre L. Moreira et al. Journal of Thoracic Oncology
- Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials
- (2015) James Chih-Hsin Yang et al. LANCET ONCOLOGY
- Targeting the DNA Damage Response in Cancer
- (2015) Mark J. O’Connor MOLECULAR CELL
- AZD9291 in EGFR Inhibitor–Resistant Non–Small-Cell Lung Cancer
- (2015) Pasi A. Jänne et al. NEW ENGLAND JOURNAL OF MEDICINE
- Bortezomib-Based Therapy for Newly Diagnosed Mantle-Cell Lymphoma
- (2015) Tadeusz Robak et al. NEW ENGLAND JOURNAL OF MEDICINE
- DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer
- (2015) Joaquin Mateo et al. NEW ENGLAND JOURNAL OF MEDICINE
- Quercetin induces human colon cancer cells apoptosis by inhibiting the nuclear factor-kappa B Pathway
- (2015) Xiang-An Zhang et al. Pharmacognosy Magazine
- The Personalization of Therapy: Molecular Profiling Technologies and Their Application
- (2015) Jorge Zeron-Medina et al. SEMINARS IN ONCOLOGY
- Atypical Protein Kinase C Zeta: Potential Player in Cell Survival and Cell Migration of Ovarian Cancer
- (2015) Kelly K. Y. Seto et al. PLoS One
- Nutlin-3a: A Potential Therapeutic Opportunity for TP53 Wild-Type Ovarian Carcinomas
- (2015) Erin K. Crane et al. PLoS One
- PIK3CA Mutations in Advanced Cancers: Characteristics and Outcomes
- (2015) Filip Janku et al. Oncotarget
- Low ATM protein expression and depletion of p53 correlates with olaparib sensitivity in gastric cancer cell lines
- (2014) Eiji Kubota et al. CELL CYCLE
- The sensitivity of gastric cancer to trastuzumab is regulated by the miR-223/FBXW7 pathway
- (2014) Kojiro Eto et al. INTERNATIONAL JOURNAL OF CANCER
- Comprehensive High-Throughput RNA Sequencing Analysis Reveals Contamination of Multiple Nasopharyngeal Carcinoma Cell Lines with HeLa Cell Genomes
- (2014) M. J. Strong et al. JOURNAL OF VIROLOGY
- Comprehensive molecular profiling of lung adenocarcinoma
- (2014) Eric A. Collisson et al. NATURE
- Whole-exome and targeted gene sequencing of gallbladder carcinoma identifies recurrent mutations in the ErbB pathway
- (2014) Maolan Li et al. NATURE GENETICS
- The genomic landscape of nasopharyngeal carcinoma
- (2014) De-Chen Lin et al. NATURE GENETICS
- Contribution of p53 to Metastasis
- (2014) E. Powell et al. Cancer Discovery
- Assessing PIK3CA and PTEN in Early-Phase Trials with PI3K/AKT/mTOR Inhibitors
- (2014) Filip Janku et al. Cell Reports
- Targeting PI3K/Akt/mTOR Signaling in Cancer
- (2014) Camillo Porta et al. Frontiers in Oncology
- Genetic deregulation of the PIK3CA oncogene in oral cancer
- (2013) Avaniyapuram Kannan Murugan et al. CANCER LETTERS
- ATM-depletion in breast cancer cells confers sensitivity to PARP inhibition
- (2013) Maria Gilardini Montani et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Individualized therapy for metastatic colorectal cancer
- (2013) A. Silvestri et al. JOURNAL OF INTERNAL MEDICINE
- Constitutive activation of distinct NF-κB signals in EBV-associated nasopharyngeal carcinoma
- (2013) Grace Tin-Yun Chung et al. JOURNAL OF PATHOLOGY
- A retrospective analysis of 335 Japanese lung cancer patients who responded to initial gefitinib treatment
- (2013) K. Nishino et al. LUNG CANCER
- Signatures of mutational processes in human cancer
- (2013) Ludmil B. Alexandrov et al. NATURE
- Evidence for APOBEC3B mutagenesis in multiple human cancers
- (2013) Michael B Burns et al. NATURE GENETICS
- Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
- (2013) NEW ENGLAND JOURNAL OF MEDICINE
- Id-1 and the p65 subunit of NF-κB promote migration of nasopharyngeal carcinoma cells and are correlated with poor prognosis
- (2012) Wei Sun et al. CARCINOGENESIS
- Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53
- (2012) Chris T. Williamson et al. EMBO Molecular Medicine
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer
- (2012) Jonathan Ledermann et al. NEW ENGLAND JOURNAL OF MEDICINE
- Role of the ubiquitin ligase Fbw7 in cancer progression
- (2011) Yabin Cheng et al. CANCER AND METASTASIS REVIEWS
- PIK3CA Mutations in Patients with Advanced Cancers Treated with PI3K/AKT/mTOR Axis Inhibitors
- (2011) F. Janku et al. MOLECULAR CANCER THERAPEUTICS
- Integrative genomics viewer
- (2011) James T Robinson et al. NATURE BIOTECHNOLOGY
- A framework for variation discovery and genotyping using next-generation DNA sequencing data
- (2011) Mark A DePristo et al. NATURE GENETICS
- Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation
- (2011) Paul B. Chapman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Fast and accurate long-read alignment with Burrows–Wheeler transform
- (2010) Heng Li et al. BIOINFORMATICS
- Association of nuclear factor κB expression with a poor outcome in nasopharyngeal carcinoma
- (2010) Y. Zhang et al. MEDICAL ONCOLOGY
- RHOA and PRKCZ control different aspects of cell motility in pancreatic cancer metastatic clones
- (2010) Marco Peruta et al. Molecular Cancer
- A method and server for predicting damaging missense mutations
- (2010) Ivan A Adzhubei et al. NATURE METHODS
- ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data
- (2010) K. Wang et al. NUCLEIC ACIDS RESEARCH
- Treatment for metastatic nasopharyngeal carcinoma
- (2010) Y. Bensouda et al. European Annals of Otorhinolaryngology-Head and Neck Diseases
- KRAS Mutation in Colon Cancer: A Marker of Resistance to EGFR-I Therapy
- (2009) Ahmad D. Siddiqui et al. ANNALS OF SURGICAL ONCOLOGY
- A small molecule inhibitor of NF-κB, dehydroxymethylepoxyquinomicin (DHMEQ), suppresses growth and invasion of nasopharyngeal carcinoma (NPC) cells
- (2009) Jason Ho Ting Wong et al. CANCER LETTERS
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- (2009) L.D. Covassin et al. DEVELOPMENTAL BIOLOGY
- KRAS mutations and resistance to EGFR-TKIs treatment in patients with non-small cell lung cancer: A meta-analysis of 22 studies
- (2009) Chen Mao et al. LUNG CANCER
- Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy
- (2008) Sanjeev Shangary et al. Annual Review of Pharmacology and Toxicology
- Authentication of nasopharyngeal carcinoma tumor lines
- (2008) Sylvia Yat-Yee Chan et al. INTERNATIONAL JOURNAL OF CANCER
- PIK3CA mutation occurs in nasopharyngeal carcinoma but does not significantly influence the disease-specific survival
- (2008) Chu-Chung Chou et al. MEDICAL ONCOLOGY
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