Lubricin Restoration in a Mouse Model of Congenital Deficiency

Anti-Lubricin Monoclonal Antibodies Created Using Lubricin-Knockout Mice Immunodetect Lubricin in Several Species and in Patients with Healthy and Diseased Joints

(2015) Minrong Ai et al.   PLoS One

Identification of aPrg4-Expressing Articular Cartilage Progenitor Cell Population in Mice

(2015) Elena Kozhemyakina et al.   Arthritis & Rheumatology

An RNA-seq protocol to identify mRNA expression changes in mouse diaphyseal bone: Applications in mice with bone property alteringLrp5mutations

(2013) Ugur M Ayturk et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Role of lubricin and boundary lubrication in the prevention of chondrocyte apoptosis

(2013) K. A. Waller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteoglycan 4 Expression Protects Against the Development of Osteoarthritis

(2013) M. Z. C. Ruan et al.   Science Translational Medicine

Camptodactyly-arthropathy-coxavara-pericarditis syndrome in Saudi Arabia: Clinical and molecular genetic findings in 22 patients

(2013) Intisar Albuhairan et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Heritability of articular cartilage regeneration and its association with ear wound healing in mice

(2012) Muhammad Farooq Rai et al.   ARTHRITIS AND RHEUMATISM

Genetic epidemiology of osteoarthritis

(2012) Marc C. Hochberg et al.   CURRENT OPINION IN RHEUMATOLOGY

Generation of a conditional mouse model to targetAcvr1bdisruption in adult tissues

(2012) Doriane Ripoche et al.   GENESIS

An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice

(2012) Kathryn M. Kinross et al.   JOURNAL OF CLINICAL INVESTIGATION

Preventing Friction-induced Chondrocyte Apoptosis: Comparison of Human Synovial Fluid and Hylan G-F 20

(2012) KIMBERLY A. WALLER et al.   JOURNAL OF RHEUMATOLOGY

The impact of forced joint exercise on lubricin biosynthesis from articular cartilage following ACL transection and intra-articular lubricin's effect in exercised joints following ACL transection

(2012) K.A. Elsaid et al.   OSTEOARTHRITIS AND CARTILAGE

Epidemiology of Osteoarthritis

(2012) Tuhina Neogi et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number

(2011) Benjamin J. Hindson et al.   ANALYTICAL CHEMISTRY

Cyclic loading increases friction and changes cartilage surface integrity in lubricin-mutant mouse knees

(2011) Elizabeth I. Drewniak et al.   ARTHRITIS AND RHEUMATISM

Prevention of cartilage degeneration and gait asymmetry by lubricin tribosupplementation in the rat following anterior cruciate ligament transection

(2011) Gregory D. Jay et al.   ARTHRITIS AND RHEUMATISM

Post-traumatic osteoarthritis: Improved understanding and opportunities for early intervention

(2011) Donald D. Anderson et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Effects of Supplemental Intra-articular Lubricin and Hyaluronic Acid on the Progression of Posttraumatic Arthritis in the Anterior Cruciate Ligament–Deficient Rat Knee

(2010) Erin Teeple et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Loss of cartilage structure, stiffness, and frictional properties in mice lacking PRG4

(2010) Jeffrey M. Coles et al.   ARTHRITIS AND RHEUMATISM

Prevention of cartilage degeneration and restoration of chondroprotection by lubricin tribosupplementation in the rat following anterior cruciate ligament transection

(2010) Gregory D. Jay et al.   ARTHRITIS AND RHEUMATISM

Prostaglandin (PG)D2 and 15-deoxy-Δ12,14-PGJ2, but not PGE2, mediate shear-induced chondrocyte apoptosis via protein kinase A-dependent regulation of polo-like kinases

(2010) F Zhu et al.   CELL DEATH AND DIFFERENTIATION

Mechanical impact induces cartilage degradation via mitogen activated protein kinases

(2010) L. Ding et al.   OSTEOARTHRITIS AND CARTILAGE

Basic methods in histopathology of joint tissues

(2010) N. Schmitz et al.   OSTEOARTHRITIS AND CARTILAGE

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the dog

(2010) J.L. Cook et al.   OSTEOARTHRITIS AND CARTILAGE

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse

(2010) S.S. Glasson et al.   OSTEOARTHRITIS AND CARTILAGE

Prolonged Application of High Fluid Shear to Chondrocytes Recapitulates Gene Expression Profiles Associated with Osteoarthritis

(2010) Fei Zhu et al.   PLoS One

Role of p53 in human chondrocyte apoptosis in response to shear strain

(2009) Shingo Hashimoto et al.   ARTHRITIS AND RHEUMATISM

Prevention of cartilage degeneration in a rat model of osteoarthritis by intraarticular treatment with recombinant lubricin

(2009) Carl R. Flannery et al.   ARTHRITIS AND RHEUMATISM

Comparison of two methods for calculating the frictional properties of articular cartilage using a simple pendulum and intact mouse knee joints

(2009) Elizabeth I. Drewniak et al.   JOURNAL OF BIOMECHANICS

High-resolution spatial mapping of shear properties in cartilage

(2009) Mark R. Buckley et al.   JOURNAL OF BIOMECHANICS

Decreased lubricin concentrations and markers of joint inflammation in the synovial fluid of patients with anterior cruciate ligament injury

(2008) K. A. Elsaid et al.   ARTHRITIS AND RHEUMATISM

Mapping the depth dependence of shear properties in articular cartilage

(2008) Mark R. Buckley et al.   JOURNAL OF BIOMECHANICS

Osteoarthritis in patients with anterior cruciate ligament rupture: A review of risk factors

(2008) Hugues Louboutin et al.   KNEE