Prolonged Application of High Fluid Shear to Chondrocytes Recapitulates Gene Expression Profiles Associated with Osteoarthritis

Hyaluronan-binding receptors: possible involvement in osteoarthritis

(2014) Sharon Dunn et al.   Modern Rheumatology

Prostaglandin E2 induces interleukin-6 expression in human chondrocytes via cAMP/protein kinase A- and phosphatidylinositol 3-kinase-dependent NF-κB activation

(2010) Pu Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Prostaglandin (PG)D2 and 15-deoxy-Δ12,14-PGJ2, but not PGE2, mediate shear-induced chondrocyte apoptosis via protein kinase A-dependent regulation of polo-like kinases

(2010) F Zhu et al.   CELL DEATH AND DIFFERENTIATION

Shear-induced Interleukin-6 Synthesis in Chondrocytes

(2010) Pu Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis

(2010) C. Karlsson et al.   OSTEOARTHRITIS AND CARTILAGE

A critical role of Cyr61 in interleukin-17–dependent proliferation of fibroblast-like synoviocytes in rheumatoid arthritis

(2009) Qiuyu Zhang et al.   ARTHRITIS AND RHEUMATISM

Increase of RhoB in γ-radiation-induced apoptosis is regulated by c-Jun N-terminal kinase in Jurkat T cells

(2009) Chun-Ho Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Modulating hedgehog signaling can attenuate the severity of osteoarthritis

(2009) Alvin C Lin et al.   NATURE MEDICINE

The retinoic acid binding protein CRABP2 is increased in murine models of degenerative joint disease

(2009) Ian D Welch et al.   ARTHRITIS RESEARCH & THERAPY

Elucidation of the signaling network of COX-2 induction in sheared chondrocytes: COX-2 is induced via a Rac/MEKK1/MKK7/JNK2/c-Jun-C/EBPβ-dependent pathway

(2008) Zachary R. Healy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism

(2008) M B Goldring et al.   ANNALS OF THE RHEUMATIC DISEASES

Innate immune system activation in osteoarthritis: is osteoarthritis a chronic wound?

(2008) Carla R Scanzello et al.   CURRENT OPINION IN RHEUMATOLOGY

Proinflammatory role of amphiregulin, an epidermal growth factor family member whose expression is augmented in rheumatoid arthritis patients

(2008) Shoji Yamane et al.   Journal of Inflammation-London

Selective COX-2 inhibitors modulate cellular senescence in human dermal fibroblasts in a catalytic activity-independent manner

(2008) So Ra Kim et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Comparative analysis of gene expression profiles between the normal human cartilage and the one with endemic osteoarthritis

(2008) W.Z. Wang et al.   OSTEOARTHRITIS AND CARTILAGE

Increased expression of lipocalin-type prostaglandin D2 synthase in osteoarthritic cartilage

(2008) Nadia Zayed et al.   ARTHRITIS RESEARCH & THERAPY

Structure–function properties of the apoE-dependent COX-2 pathway in vascular smooth muscle cells

(2007) Kamilah Ali et al.   ATHEROSCLEROSIS