PAK4 interacts with p85 alpha: implications for pancreatic cancer cell migration

Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation

(2016) Christopher J. Tape et al.   CELL

PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion

(2015) Anna E. Dart et al.   JOURNAL OF CELL BIOLOGY

p-21 activated kinase 4 promotes proliferation and survival of pancreatic cancer cells through AKT- and ERK-dependent activation of NF-κB pathway

(2015) Nikhil Tyagi et al.   Oncotarget

Wnt5a promotes migration of human osteosarcoma cells by triggering a phosphatidylinositol-3 kinase/Akt signals

(2014) Ailiang Zhang et al.   Cancer Cell International

The role of the hepatocyte growth factor/c-MET pathway in pancreatic stellate cell–endothelial cell interactions: antiangiogenic implications in pancreatic cancer

(2014) Mishaal B. Patel et al.   CARCINOGENESIS

Role of c-Met/Phosphatidylinositol 3-Kinase (PI3k)/Akt Signaling in Hepatocyte Growth Factor (HGF)-mediated Lamellipodia Formation, Reactive Oxygen Species (ROS) Generation, and Motility of Lung Endothelial Cells

(2014) Peter V. Usatyuk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emerging role of the KRAS-PDK1 axis in pancreatic cancer

(2014) Riccardo Ferro   WORLD JOURNAL OF GASTROENTEROLOGY

Selective Requirement of PI3K/PDK1 Signaling for Kras Oncogene-Driven Pancreatic Cell Plasticity and Cancer

(2013) Stefan Eser et al.   CANCER CELL

P21-activated kinase 4 – Not just one of the PAK

(2013) Anna E. Dart et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

PKB/Akt-Dependent Regulation of Cell Motility

(2013) G. Xue et al.   JNCI-Journal of the National Cancer Institute

Systems-wide Analysis of K-Ras, Cdc42, and PAK4 Signaling by Quantitative Phosphoproteomics

(2013) Florian Gnad et al.   MOLECULAR & CELLULAR PROTEOMICS

PAK4 kinase-mediated SCG10 phosphorylation involved in gastric cancer metastasis

(2013) Q Guo et al.   ONCOGENE

Mutant TP53 in Duodenal Samples of Pancreatic Juice From Patients With Pancreatic Cancer or High-Grade Dysplasia

(2012) Mitsuro Kanda et al.   Clinical Gastroenterology and Hepatology

Group I and II mammalian PAKs have different modes of activation by Cdc42

(2012) Yohendran Baskaran et al.   EMBO REPORTS

PAK4 kinase activity and somatic mutation promote carcinoma cell motility and influence inhibitor sensitivity

(2012) A D Whale et al.   ONCOGENE

Receptor-Specific Mechanisms Regulate Phosphorylation of AKT at Ser473: Role of RICTOR in β1 Integrin-Mediated Cell Survival

(2012) Anjum Riaz et al.   PLoS One

Functional cooperativity by direct interaction between PAK4 and MMP-2 in the regulation of anoikis resistance, migration and invasion in glioma

(2012) D Kesanakurti et al.   Cell Death & Disease

Notice of Retraction

(2011)   CARCINOGENESIS

Activation of the PIK3CA/AKT Pathway Suppresses Senescence Induced by an Activated RAS Oncogene to Promote Tumorigenesis

(2011) Alyssa L. Kennedy et al.   MOLECULAR CELL

Copy number alterations in pancreatic cancer identify recurrentPAK4amplification

(2010) Shuaili Chen et al.   CANCER BIOLOGY & THERAPY

PAK4: a pluripotent kinase that regulates prostate cancer cell adhesion

(2010) C. M. Wells et al.   JOURNAL OF CELL SCIENCE

β-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice

(2010) John P. Morris et al.   JOURNAL OF CLINICAL INVESTIGATION

The emerging mechanisms of isoform-specific PI3K signalling

(2010) Bart Vanhaesebroeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Phenotype and Genotype of Pancreatic Cancer Cell Lines

(2010) Emily L. Deer et al.   PANCREAS

Organotypic Culture Model of Pancreatic Cancer Demonstrates that Stromal Cells Modulate E-Cadherin, β-Catenin, and Ezrin Expression in Tumor Cells

(2009) Fieke E.M. Froeling et al.   AMERICAN JOURNAL OF PATHOLOGY

Pak4, a Novel Gab1 Binding Partner, Modulates Cell Migration and Invasion by the Met Receptor

(2009) G. N. Paliouras et al.   MOLECULAR AND CELLULAR BIOLOGY

A PAK4–LIMK1 pathway drives prostate cancer cell migration downstream of HGF

(2008) Tasneem Ahmed et al.   CELLULAR SIGNALLING

A novel function of colony-stimulating factor 1 receptor in hTERT immortalization of human epithelial cells

(2008) N F Li et al.   ONCOGENE

PI3K pathway alterations in cancer: variations on a theme

(2008) T L Yuan et al.   ONCOGENE

Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer

(2008) A. C. Kimmelman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA