Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis
Authors
Keywords
-
Journal
Scientific Reports
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-10-31
DOI
10.1038/srep36214
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22
- (2016) Marianne R. Spalinger et al. JOURNAL OF CLINICAL INVESTIGATION
- A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly
- (2016) Florian I. Schmidt et al. JOURNAL OF EXPERIMENTAL MEDICINE
- ASC filament formation serves as a signal amplification mechanism for inflammasomes
- (2016) Mathias S. Dick et al. Nature Communications
- TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation
- (2015) Takashi Watanabe et al. JOURNAL OF CELL BIOLOGY
- Syk is involved in NLRP3 inflammasome-mediated caspase-1 activation through adaptor ASC phosphorylation and enhanced oligomerization
- (2015) Ying-Cing Lin et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Inflammasomes: mechanism of action, role in disease and therapeutics
- (2015) Haitao Guo et al. NATURE MEDICINE
- FAK signaling in human cancer as a target for therapeutics
- (2015) Brian Y. Lee et al. PHARMACOLOGY & THERAPEUTICS
- Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation
- (2015) Annette Ives et al. Nature Communications
- Bruton’s tyrosine kinase is essential for NLRP3 inflammasome activation and contributes to ischaemic brain injury
- (2015) Minako Ito et al. Nature Communications
- Prion-like Polymerization Underlies Signal Transduction in Antiviral Immune Defense and Inflammasome Activation
- (2014) Xin Cai et al. CELL
- Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
- (2014) Alvin Lu et al. CELL
- Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement
- (2014) Nicole M. Chapman et al. IMMUNOLOGIC RESEARCH
- The Microtubule-associated Protein EB1 Links AIM2 Inflammasomes with Autophagy-dependent Secretion
- (2014) Li-Jie Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Signaling Mechanism of HIV-1 gp120 and Virion-Induced IL-1 Release in Primary Human Macrophages
- (2014) R. Cheung et al. JOURNAL OF IMMUNOLOGY
- Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation
- (2013) Y-H Wu et al. CELL DEATH AND DIFFERENTIATION
- Sorafenib induces autophagy and suppresses activation of human macrophage
- (2013) Jiunn-Chang Lin et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity
- (2013) Hideki Hara et al. NATURE IMMUNOLOGY
- Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome
- (2013) Takuma Misawa et al. NATURE IMMUNOLOGY
- Kinases conquer the inflammasomes
- (2013) Konstantin Neumann et al. NATURE IMMUNOLOGY
- Cdc42 regulates neutrophil migration via crosstalk between WASp, CD11b, and microtubules
- (2012) S. Kumar et al. BLOOD
- Tumour inflammasome-derived IL-1β recruits neutrophils and improves local recurrence-free survival in EBV-induced nasopharyngeal carcinoma
- (2012) Lih-Chyang Chen et al. EMBO Molecular Medicine
- Interactome-wide Analysis Identifies End-binding Protein 1 as a Crucial Component for the Speck-like Particle Formation of Activated Absence in Melanoma 2 (AIM2) Inflammasomes
- (2012) Li-Jie Wang et al. MOLECULAR & CELLULAR PROTEOMICS
- Novel role of PKR in inflammasome activation and HMGB1 release
- (2012) Ben Lu et al. NATURE
- Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity
- (2011) Taro Kawai et al. IMMUNITY
- Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling
- (2011) Haitao Wen et al. NATURE IMMUNOLOGY
- Tumor suppressor death-associated protein kinase is required for full IL-1 production
- (2010) Y.-T. Chuang et al. BLOOD
- Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions
- (2010) M. D. Schaller JOURNAL OF CELL SCIENCE
- Macrophage motility requires distinct α5β1/FAK and α4β1/paxillin signaling events
- (2010) Michelle Y. Abshire et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
- (2009) Olaf Gross et al. NATURE
- Malarial Hemozoin Activates the NLRP3 Inflammasome through Lyn and Syk Kinases
- (2009) Marina Tiemi Shio et al. PLoS Pathogens
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search