Interactome-wide Analysis Identifies End-binding Protein 1 as a Crucial Component for the Speck-like Particle Formation of Activated Absence in Melanoma 2 (AIM2) Inflammasomes

Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor

(2012) Tengchuan Jin et al.   IMMUNITY

Inflammasome polymorphisms confer susceptibility to sporadic malignant melanoma

(2012) Deepti Verma et al.   Pigment Cell & Melanoma Research

Rac1 Regulates the NLRP3 Inflammasome Which Mediates IL-1beta Production in Chlamydophila pneumoniae Infected Human Mononuclear Cells

(2012) Julia Eitel et al.   PLoS One

Tumor Suppressor RARRES1 Regulates DLG2, PP2A, VCP, EB1, and Ankrd26

(2012) Ziad J. Sahab et al.   Journal of Cancer

The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases

(2011) Beckley K. Davis et al.   Annual Review of Immunology

Inflammasomes as molecular mediators of inflammation and cancer: Potential role in melanoma

(2011) Jeffrey H. Dunn et al.   CANCER LETTERS

Inflammasome-mediated suppression of inflammation-induced colorectal cancer progression is mediated by direct regulation of epithelial cell proliferation

(2011) Bo Hu et al.   CELL CYCLE

The inflammasome: in memory of Dr. Jurg Tschopp

(2011) M Dagenais et al.   CELL DEATH AND DIFFERENTIATION

Molecular mechanisms of inflammasome activation during microbial infections

(2011) Petr Broz et al.   IMMUNOLOGICAL REVIEWS

Identification of Guanylate-Binding Protein 1 as a Potential Oral Cancer Marker Involved in Cell Invasion Using Omics-Based Analysis

(2011) Chia-Jung Yu et al.   JOURNAL OF PROTEOME RESEARCH

Secretome-Based Identification of ULBP2 as a Novel Serum Marker for Pancreatic Cancer Detection

(2011) Ya-Ting Chang et al.   PLoS One

Nasopharyngeal carcinoma

(2010) A. T. C. Chan   ANNALS OF ONCOLOGY

The antiapoptotic protein, FLIP, is regulated by heterogeneous nuclear ribonucleoprotein K and correlates with poor overall survival of nasopharyngeal carcinoma patients

(2010) L-C Chen et al.   CELL DEATH AND DIFFERENTIATION

Microtubule tip-interacting proteins: a view from both ends

(2010) Kai Jiang et al.   CURRENT OPINION IN CELL BIOLOGY

Multiplexed immunobead-based profiling of cytokine markers for detection of nasopharyngeal carcinoma and prognosis of patient survival

(2010) Kai-Ping Chang et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

(2010) Irving C. Allen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-18 Production Downstream of the Nlrp3 Inflammasome Confers Protection against Colorectal Tumor Formation

(2010) M. H. Zaki et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: NLRC5-Dependent Activation of the Inflammasome

(2010) B. K. Davis et al.   JOURNAL OF IMMUNOLOGY

A novel role for TNFAIP2: its correlation with invasion and metastasis in nasopharyngeal carcinoma

(2010) Lih-Chyang Chen et al.   MODERN PATHOLOGY

Proteome-wide Dysregulation by PRA1 Depletion Delineates a Role of PRA1 in Lipid Transport and Cell Migration

(2010) Hao-Ping Liu et al.   MOLECULAR & CELLULAR PROTEOMICS

Inflammatory Stimuli Regulate Caspase Substrate Profiles

(2010) Nicholas J. Agard et al.   MOLECULAR & CELLULAR PROTEOMICS

A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci

(2010) Jin-Xin Bei et al.   NATURE GENETICS

Migration and actin protrusion in melanoma cells are regulated by EB1 protein

(2009) Joseph M. Schober et al.   CANCER LETTERS

An EB1-Binding Motif Acts as a Microtubule Tip Localization Signal

(2009) Srinivas Honnappa et al.   CELL

The S. Typhimurium Effector SopE Induces Caspase-1 Activation in Stromal Cells to Initiate Gut Inflammation

(2009) Andreas J. Müller et al.   Cell Host & Microbe

Constitutively Active Inflammasome in Human Melanoma Cells Mediating Autoinflammation via Caspase-1 Processing and Secretion of Interleukin-1β

(2009) Miyako Okamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Levels of Retinoic Acid-Inducible Gene I Are Regulated by Heat Shock Protein 90- 

(2009) T. Matsumiya et al.   JOURNAL OF IMMUNOLOGY

Titin-based mechanical signalling in normal and failing myocardium

(2009) Martina Krüger et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Proteomic Analysis of Microtubule-associated Proteins during Macrophage Activation

(2009) Prerna C. Patel et al.   MOLECULAR & CELLULAR PROTEOMICS

Quantitative Proteomic Profiling of Prostate Cancer Reveals a Role for miR-128 in Prostate Cancer

(2009) Amjad P. Khan et al.   MOLECULAR & CELLULAR PROTEOMICS

Functional characterization of cohesin SMC3 and separase and their roles in the segregation of large and minichromosomes inTrypanosoma brucei

(2009) Mohamed Bessat et al.   MOLECULAR MICROBIOLOGY

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

(2009) Teresa Fernandes-Alnemri et al.   NATURE

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production

(2009) Hendrik Poeck et al.   NATURE IMMUNOLOGY

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

Thymidine phosphorylase mRNA stability and protein levels are increased through ERK-mediated cytoplasmic accumulation of hnRNP K in nasopharyngeal carcinoma cells

(2009) L-C Chen et al.   ONCOGENE

Molecular mechanisms involved in inflammasome activation

(2009) Clare Bryant et al.   TRENDS IN CELL BIOLOGY

Thrombospondins: from structure to therapeutics

(2008) S. Kazerounian et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Heterogeneous Ribonucleoprotein K and Thymidine Phosphorylase Are Independent Prognostic and Therapeutic Markers for Nasopharyngeal Carcinoma

(2008) L.-C. Chen et al.   CLINICAL CANCER RESEARCH

Association of IL-1B Gene Polymorphisms with Nasopharyngeal Carcinoma in a Chinese Population

(2008) Yinhua Zhu et al.   CLINICAL ONCOLOGY

Proteomic profiling reveals the prognostic value of adenomatous polyposis coli-end-binding protein 1 in hepatocellular carcinoma

(2008) Tatsuya Orimo et al.   HEPATOLOGY

An Assessment of Software Solutions for the Analysis of Mass Spectrometry Based Quantitative Proteomics Data

(2008) Lukas N. Mueller et al.   JOURNAL OF PROTEOME RESEARCH

Robust and Sensitive iTRAQ Quantification on an LTQ Orbitrap Mass Spectrometer

(2008) Marcus Bantscheff et al.   MOLECULAR & CELLULAR PROTEOMICS

Discovery and Verification of Head-and-neck Cancer Biomarkers by Differential Protein Expression Analysis Using iTRAQ Labeling, Multidimensional Liquid Chromatography, and Tandem Mass Spectrometry

(2008) Ranju Ralhan et al.   MOLECULAR & CELLULAR PROTEOMICS

Targeted Peptidecentric Proteomics Reveals Caspase-7 as a Substrate of the Caspase-1 Inflammasomes

(2008) Mohamed Lamkanfi et al.   MOLECULAR & CELLULAR PROTEOMICS