Mycobacterium tuberculosis-triggered Hippo pathway orchestrates CXCL1/2 expression to modulate host immune responses

Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation

(2016) Fansen Meng et al.   GENES & DEVELOPMENT

Immune activation of the host cell induces drug tolerance inMycobacterium tuberculosisboth in vitro and in vivo

(2016) Yancheng Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

(2015) Robert O. Watson et al.   Cell Host & Microbe

Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1

(2015) Ruth Wassermann et al.   Cell Host & Microbe

New insights into TB physiology suggest untapped therapeutic opportunities

(2015) Christina E. Baer et al.   IMMUNOLOGICAL REVIEWS

The Mammalian Sterile 20–like 1 Kinase Controls Selective CCR7-Dependent Functions in Human Dendritic Cells

(2015) Jesús Torres-Bacete et al.   JOURNAL OF IMMUNOLOGY

Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity

(2015) Jing Geng et al.   NATURE IMMUNOLOGY

The non-canonical Hippo/Mst pathway in lymphocyte development and functions

(2014) X. Du et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Selective inhibition of IFNG-induced autophagy byMir155- andMir31-responsive WNT5A and SHH signaling

(2014) Sahana Holla et al.   Autophagy

Hippo signalling directs intestinal fate

(2014) Marie Le Bouteiller et al.   NATURE CELL BIOLOGY

MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes

(2014) Amin Ardestani et al.   NATURE MEDICINE

Chemokines in tuberculosis: The good, the bad and the ugly

(2014) Leticia Monin et al.   SEMINARS IN IMMUNOLOGY

Mammalian STE20-like kinase 2, not kinase 1, mediates photoreceptor cell death during retinal detachment

(2014) H Matsumoto et al.   Cell Death & Disease

Progress in tuberculosis vaccine development and host-directed therapies—a state of the art review

(2014) Stefan H E Kaufmann et al.   Lancet Respiratory Medicine

Mast cell and macrophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation

(2013) K. De Filippo et al.   BLOOD

Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2

(2013) Yasuhiro Maejima et al.   NATURE MEDICINE

Mst1 and Mst2 kinases: regulations and diseases

(2013) Funiu Qin et al.   Cell and Bioscience

Identification of a novel role of ESAT-6-dependent miR-155 induction during infection of macrophages withMycobacterium tuberculosis

(2012) Ranjeet Kumar et al.   CELLULAR MICROBIOLOGY

The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes

(2012) Fan Mou et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Sonic hedgehog-Dependent Induction of MicroRNA 31 and MicroRNA 150 Regulates Mycobacterium bovis BCG-Driven Toll-Like Receptor 2 Signaling

(2012) Devram Sampat Ghorpade et al.   MOLECULAR AND CELLULAR BIOLOGY

Inherited MST1 Deficiency Underlies Susceptibility to EV-HPV Infections

(2012) Amandine Crequer et al.   PLoS One

Pathogen-specific TLR2 Protein Activation Programs Macrophages to Induce Wnt-β-Catenin Signaling

(2011) Kushagra Bansal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The challenge of new drug discovery for tuberculosis

(2011) Anil Koul et al.   NATURE

The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

(2011) Bin Zhao et al.   NATURE CELL BIOLOGY

IFN Regulatory Factor 3 Contributes to the Host Response during Pseudomonas aeruginosa Lung Infection in Mice

(2010) S. O. Carrigan et al.   JOURNAL OF IMMUNOLOGY

Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene

(2009) Dawang Zhou et al.   CANCER CELL

Mst1 controls lymphocyte trafficking and interstitial motility within lymph nodes

(2009) Koko Katagiri et al.   EMBO JOURNAL

MARCO, TLR2, and CD14 Are Required for Macrophage Cytokine Responses to Mycobacterial Trehalose Dimycolate and Mycobacterium tuberculosis

(2009) Dawn M. E. Bowdish et al.   PLoS Pathogens

NOTCH1 Up-regulation and Signaling Involved inMycobacterium bovisBCG-induced SOCS3 Expression in Macrophages

(2008) Yeddula Narayana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression and regulation of chemokines in mycobacterial infection

(2008) Patricia Méndez-Samperio   JOURNAL OF INFECTION