A new survivin tracer tracks, delocalizes and captures endogenous survivin at different subcellular locations and in distinct organelles

Fascin Rigidity and L-plastin Flexibility Cooperate in Cancer Cell Invadopodia and Filopodia

(2016) Isabel Van Audenhove et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ex vivo imaging of active caspase 3 by a FRET-based molecular probe demonstrates the cellular dynamics and localization of the protease in cerebellar granule cells and its regulation by the apoptosis-inhibiting protein survivin

(2016) Laura Lossi et al.   Molecular Neurodegeneration

Fascin actin bundling controls podosome turnover and disassembly while cortactin is involved in podosome assembly by its SH3 domain in THP-1 macrophages and dendritic cells

(2015) Isabel Van Audenhove et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Clinical aspects for survivin: a crucial molecule for targeting drug-resistant cancers

(2015) Neha Singh et al.   DRUG DISCOVERY TODAY

An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model

(2015) Wouter Van Overbeke et al.   HUMAN MOLECULAR GENETICS

Monitoring Interactions and Dynamics of Endogenous Beta-catenin With Intracellular Nanobodies in Living Cells

(2015) Bjoern Traenkle et al.   MOLECULAR & CELLULAR PROTEOMICS

Survivin – The inconvenient IAP

(2015) Dario C. Altieri   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Resolving bundled microtubules using anti-tubulin nanobodies

(2015) Marina Mikhaylova et al.   Nature Communications

Real-time analysis of epithelial-mesenchymal transition using fluorescent single-domain antibodies

(2015) Julia Maier et al.   Scientific Reports

The peroxisomal protein import machinery displays a preference for monomeric substrates

(2015) M. O. Freitas et al.   Open Biology

Prognostic Significance of Survivin in Breast Cancer: Meta-analysis

(2014) Yanyan Li et al.   Breast Journal

Stratifying fascin and cortactin function in invadopodium formation using inhibitory nanobodies and targeted subcellular delocalization

(2014) Isabel Van Audenhove et al.   FASEB JOURNAL

A nanobody modulates the p53 transcriptional program without perturbing its functional architecture

(2014) Jonas Bethuyne et al.   NUCLEIC ACIDS RESEARCH

Nanobodies: Natural Single-Domain Antibodies

(2013) Serge Muyldermans   Annual Review of Biochemistry

Mapping cytoskeletal protein function in cells by means of nanobodies

(2013) Isabel Van Audenhove et al.   Cytoskeleton

Impairment of Glioma Stem Cell Survival and Growth by a Novel Inhibitor for Survivin-Ran Protein Complex

(2012) H. Guvenc et al.   CLINICAL CANCER RESEARCH

Pex5p Imports Folded Tetrameric Catalase by Interaction with Pex13p

(2012) Hidenori Otera et al.   TRAFFIC

Knockdown of survivin (BIRC5) causes apoptosis in neuroblastoma via mitotic catastrophe

(2011) Fieke Lamers et al.   ENDOCRINE-RELATED CANCER

Survivin Monomer Plays an Essential Role in Apoptosis Regulation

(2011) Marat S. Pavlyukov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpression of survivin is correlated with increased invasion and metastasis of colorectal cancer

(2011) Xiao-Yuan Chu et al.   JOURNAL OF SURGICAL ONCOLOGY

Endogenous knockdown of survivin improves chemotherapeutic response in ALL models

(2011) D J Morrison et al.   LEUKEMIA

A llama-derived gelsolin single-domain antibody blocks gelsolin–G-actin interaction

(2010) Anske Van den Abbeele et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

An alpaca single-domain antibody blocks filopodia formation by obstructing L-plastin-mediated F-actin bundling

(2009) Veerle Delanote et al.   FASEB JOURNAL

Hitchhiking of Cu/Zn Superoxide Dismutase to Peroxisomes - Evidence for a Natural Piggyback Import Mechanism in Mammals

(2009) Markus Islinger et al.   TRAFFIC

Survivin gene RNA interference inhibits proliferation, induces apoptosis, and enhances radiosensitivity in HeLa cells

(2006) Hui Song et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology