A nanobody modulates the p53 transcriptional program without perturbing its functional architecture

Stratifying fascin and cortactin function in invadopodium formation using inhibitory nanobodies and targeted subcellular delocalization

(2014) Isabel Van Audenhove et al.   FASEB JOURNAL

The cytoplasmic side of p53's oncosuppressive activities

(2014) Anna Comel et al.   FEBS LETTERS

Chaperone Nanobodies Protect Gelsolin Against MT1-MMP Degradation and Alleviate Amyloid Burden in the Gelsolin Amyloidosis Mouse Model

(2014) Wouter Van Overbeke et al.   MOLECULAR THERAPY

A general protocol for the generation of Nanobodies for structural biology

(2014) Els Pardon et al.   Nature Protocols

The DNA-binding domain mediates both nuclear and cytosolic functions of p53

(2014) Ariele Viacava Follis et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Utilizing Nanobody Technology to Target Non-Immunodominant Domains of VAR2CSA

(2014) Sisse B. Ditlev et al.   PLoS One

Small molecule induced reactivation of mutant p53 in cancer cells

(2013) Xiangrui Liu et al.   NUCLEIC ACIDS RESEARCH

L-Plastin Nanobodies Perturb Matrix Degradation, Podosome Formation, Stability and Lifetime in THP-1 Macrophages

(2013) Sarah De Clercq et al.   PLoS One

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Allele-Specific p53 Mutant Reactivation

(2012) Xin Yu et al.   CANCER CELL

Nanobody-induced perturbation of LFA-1/L-plastin phosphorylation impairs MTOC docking, immune synapse formation and T cell activation

(2012) Sarah De Clercq et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Targeting breast carcinoma with radioiodinated anti-HER2 Nanobody

(2012) Marek Pruszynski et al.   NUCLEAR MEDICINE AND BIOLOGY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Gain of function of mutant p53 by coaggregation with multiple tumor suppressors

(2011) Jie Xu et al.   Nature Chemical Biology

Deconstructing p53 transcriptional networks in tumor suppression

(2011) Kathryn T. Bieging et al.   TRENDS IN CELL BIOLOGY

Analysis of p53 mutation status in human cancer cell lines: a paradigm for cell line cross-contamination

(2010) Hanna Berglind et al.   CANCER BIOLOGY & THERAPY

p53-family proteins and their regulators: hubs and spokes in tumor suppression

(2010) L Collavin et al.   CELL DEATH AND DIFFERENTIATION

A llama-derived gelsolin single-domain antibody blocks gelsolin–G-actin interaction

(2010) Anske Van den Abbeele et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Crystal Structure of the p53 Core Domain Bound to a Full Consensus Site as a Self-Assembled Tetramer

(2010) Yongheng Chen et al.   STRUCTURE

Transient Protein-Protein Interactions: Structural, Functional, and Network Properties

(2010) James R. Perkins et al.   STRUCTURE

Transcriptional Regulation by P53

(2010) R. Beckerman et al.   Cold Spring Harbor Perspectives in Biology

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

An alpaca single-domain antibody blocks filopodia formation by obstructing L-plastin-mediated F-actin bundling

(2009) Veerle Delanote et al.   FASEB JOURNAL

BclxL Changes Conformation upon Binding to Wild-type but Not Mutant p53 DNA Binding Domain

(2009) Franz Hagn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutant p53 Gain-of-Function in Cancer

(2009) M. Oren et al.   Cold Spring Harbor Perspectives in Biology

Mouse Models of p53 Functions

(2009) G. Lozano   Cold Spring Harbor Perspectives in Biology

Structural Biology of the Tumor Suppressor p53

(2008) Andreas C. Joerger et al.   Annual Review of Biochemistry

The mitochondrial p53 pathway

(2008) Angelina V. Vaseva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

(2008) Gerrit Langer et al.   Nature Protocols

Transcriptional control of human p53-regulated genes

(2008) Todd Riley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY