Structural Basis for Native Agonist and Synthetic Inhibitor Recognition by the Pseudomonas aeruginosa Quorum Sensing Regulator PqsR (MvfR)

Identification of Small-Molecule Antagonists of the Pseudomonas aeruginosa Transcriptional Regulator PqsR: Biophysically Guided Hit Discovery and Optimization

(2012) Tobias Klein et al.   ACS Chemical Biology

Crystallization and preliminary crystal structure analysis of the ligand-binding domain of PqsR (MvfR), thePseudomonasquinolone signal (PQS) responsive quorum-sensing transcription factor ofPseudomonas aeruginosa

(2012) Ningna Xu et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Purification, crystallization and preliminary X-ray diffraction analysis of the C-terminal fragment of the MvfR protein fromPseudomonas aeruginosa

(2012) Katerina Kefala et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Discovery of Antagonists of PqsR, a Key Player in 2-Alkyl-4-quinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa

(2012) Cenbin Lu et al.   CHEMISTRY & BIOLOGY

Validation of PqsD as an Anti-biofilm Target in Pseudomonas aeruginosa by Development of Small-Molecule Inhibitors

(2012) Michael P. Storz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular evolution of LysR-type transcriptional regulation in Pseudomonas aeruginosa

(2012) F. Jerry Reen et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

Role and regulation of bacterial LuxR-like regulators

(2011) Jing Chen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Simultaneous quantitative profiling of N-acyl-l-homoserine lactone and 2-alkyl-4(1H)-quinolone families of quorum-sensing signaling molecules using LC-MS/MS

(2010) Catharine A. Ortori et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

New Device for High-Throughput Viability Screening of Flow Biofilms

(2010) M. R. Benoit et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Structure-Activity Analysis of the Pseudomonas Quinolone Signal Molecule

(2010) J. Hodgkinson et al.   JOURNAL OF BACTERIOLOGY

Full-Length Structures of BenM and Two Variants Reveal Different Oligomerization Schemes for LysR-Type Transcriptional Regulators

(2010) Ajchareeya Ruangprasert et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural studies on the full-length LysR-typeregulator TsaR fromComamonas testosteroniT-2 reveal a novel open conformation of the tetrameric LTTR fold

(2010) Dominique Monferrer et al.   MOLECULAR MICROBIOLOGY

Oxygen levels rapidly modulate Pseudomonas aeruginosa social behaviours via substrate limitation of PqsH

(2010) Jeffrey W. Schertzer et al.   MOLECULAR MICROBIOLOGY

Dioxygenase-Mediated Quenching of Quinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa

(2009) Christian Pustelny et al.   CHEMISTRY & BIOLOGY

Quorum sensing and environmental adaptation in Pseudomonas aeruginosa: a tale of regulatory networks and multifunctional signal molecules

(2009) Paul Williams et al.   CURRENT OPINION IN MICROBIOLOGY

Inducer responses of BenM, a LysR-type transcriptional regulator fromAcinetobacter baylyiADP1

(2009) Sarah H. Craven et al.   MOLECULAR MICROBIOLOGY

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

Bacterial quorum sensing: a new target for anti-infective immunotherapy

(2008) Gunnar F Kaufmann et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Structure and function of the LysR-type transcriptional regulator (LTTR) family proteins

(2008) S. E. Maddocks et al.   MICROBIOLOGY-SGM

Interaction of quorum signals with outer membrane lipids: insights into prokaryotic membrane vesicle formation

(2008) Lauren Mashburn-Warren et al.   MOLECULAR MICROBIOLOGY