Mitochondrial pathogenic mechanism and degradation in optineurin E50K mutation-mediated retinal ganglion cell degeneration
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mitochondrial pathogenic mechanism and degradation in optineurin E50K mutation-mediated retinal ganglion cell degeneration
Authors
Keywords
-
Journal
Scientific Reports
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-09-22
DOI
10.1038/srep33830
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin
- (2016) Michael C. Velarde et al. Aging-US
- Mutations in the ubiquitin-binding domain of OPTN/optineurin interfere with autophagy-mediated degradation of misfolded proteins by a dominant-negative mechanism
- (2015) Wen-Chuan Shen et al. Autophagy
- Induction of autophagy in rats upon overexpression of wild-type and mutant optineurin gene
- (2015) Hongyu Ying et al. BMC CELL BIOLOGY
- The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
- (2015) Michael Lazarou et al. NATURE
- Visual impairment in an optineurin mouse model of primary open-angle glaucoma
- (2015) Henry C. Tseng et al. NEUROBIOLOGY OF AGING
- In vivo imaging of axonal transport of mitochondria in the diseased and aged mammalian CNS
- (2015) Yuji Takihara et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DRP1 inhibition rescues retinal ganglion cells and their axons by preserving mitochondrial integrity in a mouse model of glaucoma
- (2015) K-Y Kim et al. Cell Death & Disease
- Mitochondrial complex II is a source of the reserve respiratory capacity that is regulated by metabolic sensors and promotes cell survival
- (2015) J Pfleger et al. Cell Death & Disease
- Increased mitochondrial fission and volume density by blocking glutamate excitotoxicity protect glaucomatous optic nerve head astrocytes
- (2015) Won-Kyu Ju et al. GLIA
- E50K-OPTN-Induced Retinal Cell Death Involves the Rab GTPase-Activating Protein, TBC1D17 Mediated Block in Autophagy
- (2014) Madhavi Latha Somaraju Chalasani et al. PLoS One
- Oligomerization of Optineurin and Its Oxidative Stress- or E50K Mutation-Driven Covalent Cross-Linking: Possible Relationship with Glaucoma Pathology
- (2014) Jie Gao et al. PLoS One
- Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis
- (2014) X. Jiang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation
- (2014) Yvette C. Wong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of cyclophilin D by cyclosporin A promotes retinal ganglion cell survival by preventing mitochondrial alteration in ischemic injury
- (2014) S Y Kim et al. Cell Death & Disease
- M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells
- (2013) Kapil Sirohi et al. Autophagy
- Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency
- (2013) Sara Cogliati et al. CELL
- Abnormal mitochondrial transport and morphology are common pathological denominators in SOD1 and TDP43 ALS mouse models
- (2013) Jordi Magrané et al. HUMAN MOLECULAR GENETICS
- The vast complexity of primary open angle glaucoma: Disease genes, risks, molecular mechanisms and pathobiology
- (2013) Sarah F. Janssen et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Ophthalmic drug discovery: novel targets and mechanisms for retinal diseases and glaucoma
- (2012) Kang Zhang et al. NATURE REVIEWS DRUG DISCOVERY
- Depletion of optineurin in RGC-5 cells derived from retinal neurons causes apoptosis and reduces the secretion of neurotrophins
- (2011) Christiane Sippl et al. EXPERIMENTAL EYE RESEARCH
- Cell type-specific localization of optineurin in the striatal neurons of mice: implications for neuronal vulnerability in Huntington's disease
- (2011) S. Okita et al. NEUROSCIENCE
- Optineurin Is Required for CYLD-Dependent Inhibition of TNFα-Induced NF-κB Activation
- (2011) Ananthamurthy Nagabhushana et al. PLoS One
- Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth
- (2011) P. Wild et al. SCIENCE
- A new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics
- (2011) D Nguyen et al. Cell Death & Disease
- Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice
- (2010) Zai-Long Chi et al. HUMAN MOLECULAR GENETICS
- Processing of Optineurin in Neuronal Cells
- (2010) Xiang Shen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glaucoma: genes, phenotypes, and new directions for therapy
- (2010) Bao Jian Fan et al. JOURNAL OF CLINICAL INVESTIGATION
- Bax Regulates Production of Superoxide in Both Apoptotic and Nonapoptotic Neurons: Role of Caspases
- (2010) R. A. Kirkland et al. JOURNAL OF NEUROSCIENCE
- Mutations of optineurin in amyotrophic lateral sclerosis
- (2010) Hirofumi Maruyama et al. NATURE
- Differential Effects of Myocilin and Optineurin, Two Glaucoma Genes, on Neurite Outgrowth
- (2009) Takahisa Koga et al. AMERICAN JOURNAL OF PATHOLOGY
- NF-κB Mediates Tumor Necrosis Factor α-Induced Expression of Optineurin, a Negative Regulator of NF-κB
- (2009) Cherukuri Sudhakar et al. PLoS One
- Axonal protection by brain-derived neurotrophic factor associated with CREB phosphorylation in tumor necrosis factor-α-induced optic nerve degeneration
- (2008) Hiromi Fujino et al. ACTA NEUROPATHOLOGICA
- Putative partners in Bax mediated cytochrome-c release: ANT, CypD, VDAC or none of them?
- (2008) R. Kumarswamy et al. MITOCHONDRION
- Mitochondrial fragmentation in neurodegeneration
- (2008) Andrew B. Knott et al. NATURE REVIEWS NEUROSCIENCE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started