M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells

Neuronal autophagy and neurodegenerative diseases

(2012) Jin H. Son et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes

(2012) Andrea Longatti et al.   JOURNAL OF CELL BIOLOGY

Optineurin mediates a negative regulation of Rab8 by the GTPase-activating protein TBC1D17

(2012) V. Vaibhava et al.   JOURNAL OF CELL SCIENCE

Plk1-Dependent Phosphorylation of Optineurin Provides a Negative Feedback Mechanism for Mitotic Progression

(2012) David Kachaner et al.   MOLECULAR CELL

Biogenesis and Cargo Selectivity of Autophagosomes

(2011) Hilla Weidberg et al.   Annual Review of Biochemistry

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targets

(2011) Trond Lamark et al.   CELL CYCLE

Molecular genetics in glaucoma

(2011) Yutao Liu et al.   EXPERIMENTAL EYE RESEARCH

Proteome of ubiquitin/MVB pathway: possible involvement of iron-induced ubiquitylation of transferrin receptor in lysosomal degradation

(2011) Ryo Tachiyama et al.   GENES TO CELLS

Polyubiquitin Binding to Optineurin Is Required for Optimal Activation of TANK-binding Kinase 1 and Production of Interferon β

(2011) Catherine E. Gleason et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy and disease: always two sides to a problem

(2011) Sunandini Sridhar et al.   JOURNAL OF PATHOLOGY

Optineurin Is Required for CYLD-Dependent Inhibition of TNFα-Induced NF-κB Activation

(2011) Ananthamurthy Nagabhushana et al.   PLoS One

Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth

(2011) P. Wild et al.   SCIENCE

Small GTPase Rab12 Regulates Constitutive Degradation of Transferrin Receptor

(2011) Takahide Matsui et al.   TRAFFIC

Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant

(2010) Ananthamurthy Nagabhushana et al.   BMC CELL BIOLOGY

Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice

(2010) Zai-Long Chi et al.   HUMAN MOLECULAR GENETICS

Processing of Optineurin in Neuronal Cells

(2010) Xiang Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The regulation of autophagy - unanswered questions

(2010) Y. Chen et al.   JOURNAL OF CELL SCIENCE

Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane

(2010) Lisa M. Bond et al.   MOLECULAR BIOLOGY OF THE CELL

Mutations of optineurin in amyotrophic lateral sclerosis

(2010) Hirofumi Maruyama et al.   NATURE

Autophagy gone awry in neurodegenerative diseases

(2010) Esther Wong et al.   NATURE NEUROSCIENCE

Posttranslational Modifications, Localization, and Protein Interactions of Optineurin, the Product of a Glaucoma Gene

(2010) Hongyu Ying et al.   PLoS One

Impairment of Protein Trafficking upon Overexpression and Mutation of Optineurin

(2010) BumChan Park et al.   PLoS One

Optineurin Negatively Regulates the Induction of IFNβ in Response to RNA Virus Infection

(2010) Jamel Mankouri et al.   PLoS Pathogens

Life and death partners: apoptosis, autophagy and the cross-talk between them

(2009) A Eisenberg-Lerner et al.   CELL DEATH AND DIFFERENTIATION

Optineurin and Its Mutants: Molecules Associated with Some Forms of Glaucoma

(2009) Madhavi Latha Chalasani et al.   OPHTHALMIC RESEARCH

NF-κB Mediates Tumor Necrosis Factor α-Induced Expression of Optineurin, a Negative Regulator of NF-κB

(2009) Cherukuri Sudhakar et al.   PLoS One

NRP/Optineurin Cooperates with TAX1BP1 to Potentiate the Activation of NF-κB by Human T-Lymphotropic Virus Type 1 Tax Protein

(2009) Chloé Journo et al.   PLoS Pathogens