Identification of P-Rex1 as an anti-inflammatory and anti-fibrogenic target for pulmonary fibrosis

Fibrosis — A Common Pathway to Organ Injury and Failure

(2015) Don C. Rockey et al.   NEW ENGLAND JOURNAL OF MEDICINE

P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation

(2014) D. Pan et al.   BLOOD

Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis

(2013) Long Shuang Huang et al.   FASEB JOURNAL

A Critical Role for Phosphatidylinositol (3,4,5)-Trisphosphate–Dependent Rac Exchanger 1 in Endothelial Junction Disruption and Vascular Hyperpermeability

(2012) Ram P. Naikawadi et al.   CIRCULATION RESEARCH

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Characterization of P-Rex1 for its role in fMet-Leu-Phe-induced superoxide production in reconstituted COSphox cells

(2010) Baoming Nie et al.   CELLULAR SIGNALLING

Identification of the Rac-GEF P-Rex1 as an Essential Mediator of ErbB Signaling in Breast Cancer

(2010) Maria Soledad Sosa et al.   MOLECULAR CELL

P-Rex1 participates in Neuregulin-ErbB signal transduction and its expression correlates with patient outcome in breast cancer

(2010) J C Montero et al.   ONCOGENE

Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis

(2009) J Qin et al.   ONCOGENE

P-Rex1 - a multidomain protein that regulates neurite differentiation

(2008) J. E. Waters et al.   JOURNAL OF CELL SCIENCE

Murine models of pulmonary fibrosis

(2007) Bethany B. Moore et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY