A Critical Role for Phosphatidylinositol (3,4,5)-Trisphosphate–Dependent Rac Exchanger 1 in Endothelial Junction Disruption and Vascular Hyperpermeability

The PI3K p110α isoform regulates endothelial adherens junctions via Pyk2 and Rac1

(2010) Robert J. Cain et al.   JOURNAL OF CELL BIOLOGY

Identification of the Rac-GEF P-Rex1 as an Essential Mediator of ErbB Signaling in Breast Cancer

(2010) Maria Soledad Sosa et al.   MOLECULAR CELL

P-Rex1 participates in Neuregulin-ErbB signal transduction and its expression correlates with patient outcome in breast cancer

(2010) J C Montero et al.   ONCOGENE

The Regulation of Vascular Endothelial Growth Factor-induced Microvascular Permeability Requires Rac and Reactive Oxygen Species

(2009) Elizabeth Monaghan-Benson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GEF-H1 Mediates Tumor Necrosis Factor-α-induced Rho Activation and Myosin Phosphorylation

(2009) Eli Kakiashvili et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidylinositol 3,4,5-Triphosphate-Dependent Rac Exchanger 1 (P-Rex-1), a Guanine Nucleotide Exchange Factor for Rac, Mediates Angiogenic Responses to Stromal Cell-Derived Factor-1/Chemokine Stromal Cell Derived Factor-1 (SDF-1/CXCL-12) Linked to Rac Activation, Endothelial Cell Migration, and in Vitro Angiogenesis

(2009) J. Carretero-Ortega et al.   MOLECULAR PHARMACOLOGY

Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis

(2009) J Qin et al.   ONCOGENE

p120-Catenin regulates leukocyte transmigration through an effect on VE-cadherin phosphorylation

(2008) P. Alcaide et al.   BLOOD

Tiam1 and Rac1 Are Required for Platelet-activating Factor-induced Endothelial Junctional Disassembly and Increase in Vascular Permeability

(2008) Ivana I. Knezevic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P-Rex1 - a multidomain protein that regulates neurite differentiation

(2008) J. E. Waters et al.   JOURNAL OF CELL SCIENCE