Targeting sphingosine kinase 1 attenuates bleomycin-induced pulmonary fibrosis

Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate

(2012) Yugesh Kharel et al.   BIOCHEMICAL JOURNAL

Vesnarinone Represses the Fibrotic Changes in Murine Lung Injury Induced by Bleomycin

(2012) Minoru Inage et al.   International Journal of Biological Sciences

Wnt Pathway in Pulmonary Fibrosis in the Bleomycin Mouse Model

(2012) Li Liu et al.   JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY

Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression

(2012) Irina Gorshkova et al.   JOURNAL OF LIPID RESEARCH

Characterization of Isoenzyme-Selective Inhibitors of Human Sphingosine Kinases

(2012) Peng Gao et al.   PLoS One

The Lysophosphatidic Acid Receptor LPA1Promotes Epithelial Cell Apoptosis after Lung Injury

(2011) Manuela Funke et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A rapid assay for assessment of sphingosine kinase inhibitors and substrates

(2011) Yugesh Kharel et al.   ANALYTICAL BIOCHEMISTRY

Modeling pulmonary fibrosis with bleomycin

(2011) Marios A. Mouratis et al.   CURRENT OPINION IN PULMONARY MEDICINE

Intracellular S1P Generation Is Essential for S1P-Induced Motility of Human Lung Endothelial Cells: Role of Sphingosine Kinase 1 and S1P Lyase

(2011) Evgeny V. Berdyshev et al.   PLoS One

Sphingosine-1-phosphate is increased in patients with idiopathic pulmonary fibrosis and mediates epithelial to mesenchymal transition

(2011) Javier Milara et al.   THORAX

Prolonged Exposure to Sphingosine 1–Phosphate Receptor-1 Agonists Exacerbates Vascular Leak, Fibrosis, and Mortality after Lung Injury

(2010) Barry S. Shea et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Acid Sphingomyelinase Deficiency Attenuates Bleomycin-Induced Lung Inflammation and Fibrosis in Mice

(2010) Rajwinder Dhami et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

A Novel Function of Sphingosine Kinase 1 Suppression of JNK Activity in Preventing Inflammation and Injury

(2010) Anke Di et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

(2010) Gang Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SKI-II, an Inhibitor of Sphingosine Kinase, Ameliorates Antigen-Induced Bronchial Smooth Muscle Hyperresponsiveness, but Not Airway Inflammation, in Mice

(2010) Yoshihiko Chiba et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Transforming Growth Factor-β1 Induces Transdifferentiation of Myoblasts into Myofibroblasts via Up-Regulation of Sphingosine Kinase-1/S1P3 Axis

(2010) Francesca Cencetti et al.   MOLECULAR BIOLOGY OF THE CELL

S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species

(2009) Noriko Takuwa et al.   CARDIOVASCULAR RESEARCH

Two pathways for lysophosphatidic acid production

(2008) J AOKI   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Standardized quantification of pulmonary fibrosis in histological samples

(2008) Ralf-Harto Hübner et al.   BIOTECHNIQUES