Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein

Using hydrogen deuterium exchange mass spectrometry to engineer optimized constructs for crystallization of protein complexes: Case study of PI4KIIIβ with Rab11

(2016) Melissa L. Fowler et al.   PROTEIN SCIENCE

Plasticity of PI4KIII  interactions at the plasma membrane

(2015) J. Chung et al.   EMBO REPORTS

Phosphatidylinositol 4-kinases: Function, structure, and inhibition

(2015) Evzen Boura et al.   EXPERIMENTAL CELL RESEARCH

Structural insight into the calcium ion modulated interdomain electron transfer in cellobiose dehydrogenase

(2015) Alan Kadek et al.   FEBS LETTERS

Highly Selective Phosphatidylinositol 4-Kinase IIIβ Inhibitors and Structural Insight into Their Mode of Action

(2015) Ivana Mejdrová et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

The high-resolution crystal structure of phosphatidylinositol 4-kinase IIβ and the crystal structure of phosphatidylinositol 4-kinase IIα containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design

(2015) Martin Klima et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

2-Alkyloxazoles as potent and selective PI4KIIIβ inhibitors demonstrating inhibition of HCV replication

(2014) Erin P. Keaney et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The crystal structure of the phosphatidylinositol 4-kinase II 

(2014) A. Baumlova et al.   EMBO REPORTS

The Legionella longbeachae Icm/Dot Substrate SidC Selectively Binds Phosphatidylinositol 4-Phosphate with Nanomolar Affinity and Promotes Pathogen Vacuole-Endoplasmic Reticulum Interactions

(2014) Stephanie Dolinsky et al.   INFECTION AND IMMUNITY

Large, dynamic, multi-protein complexes: a challenge for structural biology

(2014) Bartosz Różycki et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

A Complex Comprising Phosphatidylinositol 4-Kinase III , ACBD3, and Aichi Virus Proteins Enhances Phosphatidylinositol 4-Phosphate Synthesis and Is Critical for Formation of the Viral Replication Complex

(2014) K. Ishikawa-Sasaki et al.   JOURNAL OF VIROLOGY

Structures of PI4KIII  complexes show simultaneous recruitment of Rab11 and its effectors

(2014) J. E. Burke et al.   SCIENCE

Structural Insights into Assembly and Regulation of the Plasma Membrane Phosphatidylinositol 4-Kinase Complex

(2013) Xudong Wu et al.   DEVELOPMENTAL CELL

Phosphoinositides: Tiny Lipids With Giant Impact on Cell Regulation

(2013) Tamas Balla   PHYSIOLOGICAL REVIEWS

Mammalian phosphatidylinositol 4-kinases as modulators of membrane trafficking and lipid signaling networks

(2013) Emma L. Clayton et al.   PROGRESS IN LIPID RESEARCH

ACBD3 Interaction with TBC1 Domain 22 Protein Is Differentially Affected by Enteroviral and Kobuviral 3A Protein Binding

(2013) A. L. Greninger et al.   mBio

Golgi Protein ACBD3 Mediates Neurotoxicity Associated with Huntington’s Disease

(2013) Juan I. Sbodio et al.   Cell Reports

Endosomal Sorting Complex Required for Transport (ESCRT) Complexes Induce Phase-separated Microdomains in Supported Lipid Bilayers

(2012) Evzen Boura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The 3A Protein from Multiple Picornaviruses Utilizes the Golgi Adaptor Protein ACBD3 To Recruit PI4KIII 

(2012) A. L. Greninger et al.   JOURNAL OF VIROLOGY

Structural basis for membrane targeting by the MVB12-associated  -prism domain of the human ESCRT-I MVB12 subunit

(2012) E. Boura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PI4P and PI(4,5)P2 Are Essential But Independent Lipid Determinants of Membrane Identity

(2012) G. R. V. Hammond et al.   SCIENCE

Phosphatidylinositol 4-kinases: hostages harnessed to build panviral replication platforms

(2012) Nihal Altan-Bonnet et al.   TRENDS IN BIOCHEMICAL SCIENCES

A homogeneous and nonisotopic assay for phosphatidylinositol 4-kinases

(2011) Andrew W. Tai et al.   ANALYTICAL BIOCHEMISTRY

ACBD3-mediated recruitment of PI4KB to picornavirus RNA replication sites

(2011) Jun Sasaki et al.   EMBO JOURNAL

Structure of the human FOXO4-DBD–DNA complex at 1.9 Å resolution reveals new details of FOXO binding to the DNA

(2010) Evzen Boura et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

14-3-3 protein interacts with and affects the structure of RGS domain of regulator of G protein signaling 3 (RGS3)

(2010) Lenka Rezabkova et al.   JOURNAL OF STRUCTURAL BIOLOGY

Acyl-coenzyme A binding domain containing 3 (ACBD3; PAP7; GCP60): An emerging signaling molecule

(2010) Jinjiang Fan et al.   PROGRESS IN LIPID RESEARCH