Challenges in the Development of Functional Assays of Membrane Proteins

Combined Electrochemistry and Surface-Enhanced Infrared Absorption Spectroscopy of Gramicidin A Incorporated into Tethered Bilayer Lipid Membranes

(2012) Jacek Kozuch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Measurement of the Mechanical Properties of Lipid Phases in Supported Bilayers

(2012) Laura Picas et al.   BIOPHYSICAL JOURNAL

Injection Molding and its application to drug delivery

(2012) Lucia Zema et al.   JOURNAL OF CONTROLLED RELEASE

Engineering de Novo Membrane-Mediated Protein–Protein Communication Networks

(2012) Kalypso Charalambous et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Supported Lipid Bilayers at Skeletonized Surfaces for the Study of Transmembrane Proteins

(2012) Roxane M. Fabre et al.   LANGMUIR

Polymer-based microfluidic device for measuring membrane protein activities

(2012) I. Hutter et al.   Microfluidics and Nanofluidics

Reading DNA at single-nucleotide resolution with a mutant MspA nanopore and phi29 DNA polymerase

(2012) Elizabeth A Manrao et al.   NATURE BIOTECHNOLOGY

Fusion of single proteoliposomes with planar, cushioned bilayers in microfluidic flow cells

(2012) Erdem Karatekin et al.   Nature Protocols

Search for Pore-fection

(2012) E. Pennisi   SCIENCE

Composition and structure of mixed phospholipid supported bilayers formed by POPC and DPPC

(2012) Anna Åkesson et al.   Soft Matter

Structure and Pharmacology of Pentameric Receptor Channels: From Bacteria to Brain

(2012) Pierre-Jean Corringer et al.   STRUCTURE

Orthogonal Functionalization of Nanoporous Substrates: Control of 3D Surface Functionality

(2011) Thomas D. Lazzara et al.   ACS Applied Materials & Interfaces

Nanopore-Based Single-Molecule Mass Spectrometry on a Lipid Membrane Microarray

(2011) Gerhard Baaken et al.   ACS Nano

Microfluidic Chips for Point-of-Care Immunodiagnostics

(2011) Luc Gervais et al.   ADVANCED MATERIALS

Techniques for recording reconstituted ion channels

(2011) Sophie Demarche et al.   ANALYST

Rapid Microfluidic Perfusion Enabling Kinetic Studies of Lipid Ion Channels in a Bilayer Lipid Membrane Chip

(2011) Chenren Shao et al.   ANNALS OF BIOMEDICAL ENGINEERING

Vesicle Fusion Observed by Content Transfer across a Tethered Lipid Bilayer

(2011) Robert J. Rawle et al.   BIOPHYSICAL JOURNAL

Lab-on-a-chip technologies for massive parallel data generation in the life sciences: A review

(2011) S.J. Trietsch et al.   CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS

Creating and Modulating Microdomains in Pore-Spanning Membranes

(2011) Alexander Orth et al.   CHEMPHYSCHEM

Simultaneous Determination of the Elastic Properties of the Lipid Bilayer by Atomic Force Microscopy: Bending, Tension, and Adhesion

(2011) Erasmo Ovalle-García et al.   JOURNAL OF PHYSICAL CHEMISTRY B

In Vitro Reconstitution of Eukaryotic Ion Channels Using Droplet Interface Bilayers

(2011) Sebastian Leptihn et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oriented Reconstitution of a Membrane Protein in a Giant Unilamellar Vesicle: Experimental Verification with the Potassium Channel KcsA

(2011) Miho Yanagisawa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Continuous Lipid Bilayers Derived from Cell Membranes for Spatial Molecular Manipulation

(2011) Lisa Simonsson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Microfluidic lipid membrane formation on microchamber arrays

(2011) Sadao Ota et al.   LAB ON A CHIP

Supported Lipid Bilayer Composition Microarray Fabricated by Pattern-Guided Self-Spreading

(2011) Kazuaki Furukawa et al.   LANGMUIR

Pore Spanning Lipid Bilayers on Mesoporous Silica Having Varying Pore Size

(2011) Maria Claesson et al.   LANGMUIR

Formation of Nanopore-Spanning Lipid Bilayers through Liposome Fusion

(2011) Karthik Kumar et al.   LANGMUIR

Simple Reconstitution of Protein Pores in Nano Lipid Bilayers

(2011) Joanne L. Gornall et al.   NANO LETTERS

The structural basis of agonist-induced activation in constitutively active rhodopsin

(2011) Jörg Standfuss et al.   NATURE

Mixing subattolitre volumes in a quantitative and highly parallel manner with soft matter nanofluidics

(2011) Sune M. Christensen et al.   Nature Nanotechnology

Trends in the exploitation of novel drug targets

(2011) Mathias Rask-Andersen et al.   NATURE REVIEWS DRUG DISCOVERY

Functional Reconstitution of a Voltage-Gated Potassium Channel in Giant Unilamellar Vesicles

(2011) Sophie Aimon et al.   PLoS One

Ligand Activation of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC

(2011) Iwan Zimmermann et al.   PLOS BIOLOGY

A Gigaseal Obtained with a Self-Assembled Long-Lifetime Lipid Bilayer on a Single Polyelectrolyte Multilayer-Filled Nanopore

(2010) Kaori Sugihara et al.   ACS Nano

Quartz Nanopore Membranes for Suspended Bilayer Ion Channel Recordings

(2010) Anna E. P. Schibel et al.   ANALYTICAL CHEMISTRY

Latest Developments in Micro Total Analysis Systems

(2010) Arun Arora et al.   ANALYTICAL CHEMISTRY

A Pharmacologically Validated, High-Capacity, Functional Thallium Flux Assay for the Human Ether-à-go-go Related Gene Potassium Channel

(2010) William A. Schmalhofer et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Profiling Diverse Compounds by Flux- and Electrophysiology-Based Primary Screens for Inhibition of Human Ether-à-go-go Related Gene Potassium Channels

(2010) Beiyan Zou et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Special issue on “Membrane Protein Dynamics: Correlating Structure to Function”

(2010) Gianluigi Veglia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Bacteriorhodopsin-based photo-electrochemical cell

(2010) Li-Kang Chu et al.   BIOSENSORS & BIOELECTRONICS

Integration and recording of a reconstituted voltage-gated sodium channel in planar lipid bilayers

(2010) A. Studer et al.   BIOSENSORS & BIOELECTRONICS

Innovation in biotechnology: moving from academic research to product development—the case of biosensors

(2010) Christina G. Siontorou et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Structure and assembly of pore-forming proteins

(2010) Ioan Iacovache et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

An electrochemical impedance study of the effect of pathogenic bacterial toxins on tethered bilayer lipid membrane

(2010) Thet Naing Tun et al.   ELECTROCHEMISTRY COMMUNICATIONS

Dynamics of supported lipid bilayer deposition from vesicle suspensions

(2010) Seyda Bucak et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

The Resistance of Polyelectrolyte Multilayers in a Free-Hanging Configuration

(2010) Kaori Sugihara et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Fractional Polymerization of a Suspended Planar Bilayer Creates a Fluid, Highly Stable Membrane for Ion Channel Recordings

(2010) Benjamin A. Heitz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pattern Formation and Molecular Transport of Histidine-Tagged GFPs Using Supported Lipid Bilayers

(2010) Hiroshi Nakashima et al.   LANGMUIR

Atomic Force Microscopy Force Mapping in the Study of Supported Lipid Bilayers†

(2010) James K. Li et al.   LANGMUIR

Transport, Separation, and Accumulation of Proteins on Supported Lipid Bilayers

(2010) J. Neumann et al.   NANO LETTERS

Quartz crystal microbalance with dissipation monitoring of supported lipid bilayers on various substrates

(2010) Nam-Joon Cho et al.   Nature Protocols

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Prediction of the human membrane proteome

(2010) Linn Fagerberg et al.   PROTEOMICS

Lipid Rafts As a Membrane-Organizing Principle

(2010) D. Lingwood et al.   SCIENCE

Liposome and Lipid Bilayer Arrays Towards Biosensing Applications

(2010) Marta Bally et al.   Small

A Polymer-Based Nanopore-Integrated Microfluidic Device for Generating Stable Bilayer Lipid Membranes

(2010) Ryuji Kawano et al.   Small

Biomimetic membranes for sensor and separation applications

(2009) Claus Hélix Nielsen   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Amphipol-Assisted in Vitro Folding of G Protein-Coupled Receptors

(2009) Tassadite Dahmane et al.   BIOCHEMISTRY

Ion binding properties and structure stability of the NaK channel

(2009) Rong Shen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Black lipid membranes stabilized through substrate conjugation to a hydrogel

(2009) Tae-Joon Jeon et al.   Biointerphases

Nano for bio: Nanopore arrays for stable and functional lipid bilayer membranes (Mini Review)

(2009) Louis X. Tiefenauer et al.   Biointerphases

Atomic Force Microscopy of Biological Membranes

(2009) Patrick L.T.M. Frederix et al.   BIOPHYSICAL JOURNAL

The impact of GPCR structures on pharmacology and structure-based drug design

(2009) Miles Congreve et al.   BRITISH JOURNAL OF PHARMACOLOGY

Predicting Ligand Interactions with ABC Transporters in ADME

(2009) Michael A. Demel et al.   CHEMISTRY & BIODIVERSITY

Formation of individual protein channels in lipid bilayers suspended in nanopores

(2009) André Studer et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Membrane injury by pore-forming proteins

(2009) Mirko Bischofberger et al.   CURRENT OPINION IN CELL BIOLOGY

Engineering G protein-coupled receptors to facilitate their structure determination

(2009) Christopher G Tate et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Membrane protein assembly into Nanodiscs

(2009) Timothy H. Bayburt et al.   FEBS LETTERS

Electrochemical sensing of the ion-channel formation of OmpF

(2009) Han Xiao et al.   JOURNAL OF APPLIED ELECTROCHEMISTRY

The Outer Membrane Protein VhOmp of Vibrio harveyi: Pore-Forming Properties in Black Lipid Membranes

(2009) Albert Schulte et al.   JOURNAL OF MEMBRANE BIOLOGY

Simultaneous Measurement of Ionic Current and Fluorescence from Single Protein Pores

(2009) Andrew J. Heron et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lipid Transfer between Charged Supported Lipid Bilayers and Oppositely Charged Vesicles

(2009) Angelika Kunze et al.   LANGMUIR

Mechanical Behavior of a Supported Lipid Bilayer under External Shear Forces

(2009) Peter Jönsson et al.   LANGMUIR

Free-Standing Lipid Bilayers in Silicon Chips−Membrane Stabilization Based on Microfabricated Apertures with a Nanometer-Scale Smoothness

(2009) Ayumi Hirano-Iwata et al.   LANGMUIR

Real-time monitoring of lipid transfer between vesicles and hybrid bilayers on Au nanoshells using surface enhanced Raman scattering (SERS)

(2009) Janardan Kundu et al.   Nanoscale

Comparative Analysis of GPCR Crystal Structures

(2009) David T. Lodowski et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Giga-seal solvent-free bilayer lipid membranes: from single nanopores to nanopore arrays

(2009) Slavoj Kresák et al.   Soft Matter

Microtechnologies for membrane protein studies

(2008) Hiroaki Suzuki et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Simultaneous Alternating and Direct Current Readout of Protein Ion Channel Blocking Events Using Glass Nanopore Membranes

(2008) Eric N. Ervin et al.   ANALYTICAL CHEMISTRY

Structure and Mechanics of Membrane Proteins

(2008) Andreas Engel et al.   Annual Review of Biochemistry

Tetrameric Bacterial Sodium Channels: Characterization of Structure, Stability, and Drug Binding†

(2008) Ghasem Nurani et al.   BIOCHEMISTRY

Interaction of the P-Glycoprotein Multidrug Efflux Pump with Cholesterol: Effects on ATPase Activity, Drug Binding and Transport†

(2008) Paul D. W. Eckford et al.   BIOCHEMISTRY

Chemically Reactive Derivatives of Gramicidin A for Developing Ion Channel-Based Nanoprobes

(2008) Steven Blake et al.   BIOCONJUGATE CHEMISTRY

Ninety-six-well planar lipid bilayer chip for ion channel recording Fabricated by hybrid stereolithography

(2008) Hiroaki Suzuki et al.   BIOMEDICAL MICRODEVICES

Electronic Wiring of a Multi-Redox Site Membrane Protein in a Biomimetic Surface Architecture

(2008) Marcel G. Friedrich et al.   BIOPHYSICAL JOURNAL

Models of the Structure and Gating Mechanisms of the Pore Domain of the NaChBac Ion Channel

(2008) Yinon Shafrir et al.   BIOPHYSICAL JOURNAL

A Method Improving the Accuracy of Fluorescence Recovery after Photobleaching Analysis

(2008) Peter Jönsson et al.   BIOPHYSICAL JOURNAL

Ion channel and toxin measurement using a high throughput lipid membrane platform

(2008) Jason L. Poulos et al.   BIOSENSORS & BIOELECTRONICS

Bilayer lipid membrane (BLM) based ion selective electrodes at the meso-, micro-, and nano-scales

(2008) Bingwen Liu et al.   BIOSENSORS & BIOELECTRONICS

Microfluidic array platform for simultaneous lipid bilayer membrane formation

(2008) M. Zagnoni et al.   BIOSENSORS & BIOELECTRONICS

Global Twisting Motion of Single Molecular KcsA Potassium Channel upon Gating

(2008) Hirofumi Shimizu et al.   CELL

Reconstitution of the voltage-gated K+ channel KAT1 in planar lipid bilayers

(2008) Shunsuke Ozaki et al.   ELECTROCHEMISTRY COMMUNICATIONS

Towards reconciling structure and function in the nuclear pore complex

(2008) Roderick Y. H. Lim et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Preparation and characterization of asymmetric planar supported bilayers composed of poly(bis-sorbylphosphatidylcholine) on n-octadecyltrichlorosilane SAMs

(2008) Saliya N. Ratnayaka et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Fabrication of highly insulating tethered bilayer lipid membrane using yeast cell membrane fractions for measuring ion channel activity

(2008) Sachin R. Jadhav et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Effects on Interactions of Oppositely Charged Phospholipid Vesicles of Covalent Attachment of Polyethylene Glycol Oligomers to Their Surfaces: Adhesion, Hemifusion, Full Fusion and “Endocytosis”

(2008) Guohua Lei et al.   JOURNAL OF MEMBRANE BIOLOGY

Cholesterol-Mediated Activation of P-Glycoprotein: Distinct Effects on Basal and Drug-Induced ATPase Activities

(2008) Sara Belli et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Bridging Across Length Scales: Multi-Scale Ordering of Supported Lipid Bilayers via Lipoprotein Self-assembly and Surface Patterning

(2008) Madhuri S. Vinchurkar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanoimprint lithography: An old story in modern times? A review

(2008) Helmut Schift   JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B

Single molecule measurements within individual membrane-bound ion channels using a polymer-based bilayer lipid membrane chip

(2008) Louis P. Hromada et al.   LAB ON A CHIP

Formation of artificial lipid bilayers using droplet dielectrophoresis

(2008) Sara Aghdaei et al.   LAB ON A CHIP

Probing the function of ionotropic and G protein-coupled receptors in surface-confined membranes

(2008) Christophe Danelon et al.   METHODS

Structure of a β1-adrenergic G-protein-coupled receptor

(2008) Tony Warne et al.   NATURE

Sensing voltage across lipid membranes

(2008) Kenton J. Swartz   NATURE

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

Artificial nanopores that mimic the transport selectivity of the nuclear pore complex

(2008) Tijana Jovanovic-Talisman et al.   NATURE

High-throughput electrophysiology: an emerging paradigm for ion-channel screening and physiology

(2008) John Dunlop et al.   NATURE REVIEWS DRUG DISCOVERY

Mechanics of Channel Gating of the Nicotinic Acetylcholine Receptor

(2008) Xinli Liu et al.   PLoS Computational Biology

Insights from biophysical studies on the role of polyunsaturated fatty acids for function of G-protein coupled membrane receptors

(2008) Klaus Gawrisch et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Structural Dynamics of an Isolated Voltage-Sensor Domain in a Lipid Bilayer

(2008) Sudha Chakrapani et al.   STRUCTURE

Membrane biosensor platforms using nano- and microporous supports

(2008) Erik Reimhult et al.   TRENDS IN BIOTECHNOLOGY

Lipid Bilayer Microarray for Parallel Recording of Transmembrane Ion Currents

(2007) Bruno Le Pioufle et al.   ANALYTICAL CHEMISTRY

Strategies to prepare and characterize native membrane proteins and protein membranes by AFM

(2007) Daniel J. Muller et al.   CURRENT OPINION IN COLLOID & INTERFACE SCIENCE

Tethered bilayer lipid membranes with giga-ohm resistances

(2007) Inga K. Vockenroth et al.   ELECTROCHEMISTRY COMMUNICATIONS

Modeling the hERG potassium channel in a phospholipid bilayer: Molecular dynamics and drug docking studies

(2007) Matteo Masetti et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY