(−)-Epigallocatechin-3-gallate (EGCG) inhibits starch digestion and improves glucose homeostasis through direct or indirect activation of PXR/CAR-mediated phase II metabolism in diabetic mice

EGCG evokes Nrf2 nuclear translocation and dampens PTP1B expression to ameliorate metabolic misalignment under insulin resistance condition

(2018) Yashi Mi et al.   Food & Function

Green tea extract ingestion, fat oxidation, and glucose tolerance in healthy humans

(2018) Michelle C Venables et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Comparison of α-amylase, α-glucosidase and lipase inhibitory activity of the phenolic substances in two black legumes of different genera

(2017) Yuqing Tan et al.   FOOD CHEMISTRY

Direct and indirect measurements of enhanced phenolic bioavailability from litchi pericarp procyanidins by Lactobacillus casei-01

(2017) Shuyi Li et al.   Food & Function

Protective role of epigallocatechin-3-gallate in health and disease: A perspective

(2016) Animesh Chowdhury et al.   BIOMEDICINE & PHARMACOTHERAPY

α-Glucosidase inhibiting activity and bioactive compounds of six red wine grape pomace extracts

(2016) Hoda C. Kadouh et al.   Journal of Functional Foods

A-type procyanidins from litchi pericarp ameliorate hyperglycaemia by regulating hepatic and muscle glucose metabolism in streptozotocin (STZ)-induced diabetic mice fed with high fat diet

(2016) Xiaopeng Li et al.   Journal of Functional Foods

Inhibition of Advanced Glycation Endproduct Formation by Lotus Seedpod Oligomeric Procyanidins through RAGE–MAPK Signaling and NF-κB Activation in High-Fat-Diet Rats

(2015) Qian Wu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

CAR Suppresses Hepatic Gluconeogenesis by Facilitating the Ubiquitination and Degradation of PGC1α

(2015) Jie Gao et al.   MOLECULAR ENDOCRINOLOGY

Mechanisms of body weight reduction and metabolic syndrome alleviation by tea

(2015) Chung S. Yang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The role of the Nrf2/Keap1 pathway in obesity and metabolic syndrome

(2014) Zhiguo Zhang et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

A Review on Structure–Activity Relationship of Dietary Polyphenols Inhibiting α-Amylase

(2013) Jianbo Xiao et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Enhanced Nrf2 Activity Worsens Insulin Resistance, Impairs Lipid Accumulation in Adipose Tissue, and Increases Hepatic Steatosis in Leptin-Deficient Mice

(2012) J. Xu et al.   DIABETES

Grape Seed and Tea Extracts and Catechin 3-Gallates Are Potent Inhibitors of α-Amylase and α-Glucosidase Activity

(2012) Meltem Yilmazer-Musa et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Inhibition of starch digestion by the green tea polyphenol, (−)-epigallocatechin-3-gallate

(2012) Sarah C. Forester et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Possible effects of dietary polyphenols on sugar absorption and digestion

(2012) Gary Williamson   MOLECULAR NUTRITION & FOOD RESEARCH

Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection

(2012) Meijuan Zhang et al.   PROGRESS IN NEUROBIOLOGY

Targeting xenobiotic receptors PXR and CAR for metabolic diseases

(2012) Jie Gao et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR

(2010) Antonia H. Tolson et al.   ADVANCED DRUG DELIVERY REVIEWS

Increased CD36 Expression Signals Monocyte Activation Among Patients With Type 2 Diabetes

(2010) Y. Sun et al.   DIABETES CARE

Pregnane X Receptor and Constitutive Androstane Receptor at the Crossroads of Drug Metabolism and Energy Metabolism

(2010) J. Gao et al.   DRUG METABOLISM AND DISPOSITION

Grape skin extract inhibits mammalian intestinal α-glucosidase activity and suppresses postprandial glycemic response in streptozocin-treated mice

(2010) Lei Zhang et al.   FOOD CHEMISTRY

Impact of Dietary Polyphenols on Carbohydrate Metabolism

(2010) Kati Hanhineva et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dietary Flavonoids Activate the Constitutive Androstane Receptor (CAR)

(2010) Ruiquing Yao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

(2010) Shijie Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insights into the metabolism and microbial biotransformation of dietary flavan-3-ols and the bioactivity of their metabolites

(2010) Maria Monagas et al.   Food & Function

Disposition of Flavonoids via Enteric Recycling: UDP-Glucuronosyltransferase (UGT) 1As Deficiency in Gunn Rats Is Compensated by Increases in UGT2Bs Activities

(2009) S. W. J. Wang et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease

(2009) B. Dong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PXR and CAR in energy metabolism

(2009) Taira Wada et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Effects of dietary supplementation with the green tea polyphenol epigallocatechin-3-gallate on insulin resistance and associated metabolic risk factors: randomized controlled trial

(2008) A. Louise Brown et al.   BRITISH JOURNAL OF NUTRITION

Selective versus Total Insulin Resistance: A Pathogenic Paradox

(2008) Michael S. Brown et al.   Cell Metabolism

Effect of green tea extract on obese women: A randomized, double-blind, placebo-controlled clinical trial

(2008) Chung-Hua Hsu et al.   CLINICAL NUTRITION

New Insights on the Xenobiotic-Sensing Nuclear Receptors in Liver Diseases – CAR and PXR-

(2008) Satoru Kakizaki et al.   CURRENT DRUG METABOLISM

Epigallocatechin gallate (EGCG) attenuates high glucose-induced insulin signaling blockade in human hepG2 hepatoma cells

(2008) Chih-Li Lin et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Regulatory Cross-Talk between Drug Metabolism and Lipid Homeostasis: Constitutive Androstane Receptor and Pregnane X Receptor Increase Insig-1 Expression

(2008) A. Roth et al.   MOLECULAR PHARMACOLOGY

Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG

(2007) Hye-Kyung Na et al.   FOOD AND CHEMICAL TOXICOLOGY

Xenoreceptors CAR and PXR Activation and Consequences on Lipid Metabolism, Glucose Homeostasis, and Inflammatory Response

(2007) Amélie Moreau et al.   MOLECULAR PHARMACEUTICS